1.Research on the active impact of the domestic breast X-ray machine upgrade at the diagnosis breast disease
Deqin YANG ; Yantao DU ; Xiongwei DING
China Medical Equipment 2013;(11):113-114
Objective:To discuss the active impact of the domestic breast X-ray machine upgrade at the diagnosis breast disease. Methods:After the transformation of domestic breast X-ray machine, adoption the IP board instead of the film cartridge, complete digital mammography system. Results:Computed X-ray imaging processing image quality is better than traditional X-ray photography piece, within two years, completed a total check of more than 400 patients, overall diagnosis rate more than 95%. Conclusion:Buy the CR system All levels of the hospital, Can take advantage of the existing the ordinary breast X-ray machine equipment, Carry out breast Digital Imaging System.
2.Humoral immune responses in rabbits with an experimental SARS-CoV inactivated vaccine
Chuanhai ZHANG ; Zhongmin GUO ; Huanying ZHENG ; Jiahai LU ; Yifei WANG ; Yong ZHAO ; Xiongwei DU ; Meiying ZHANG
Chinese Journal of Immunology 1985;0(05):-
Objective:To evaluate the immunogenicity of an experimental SARS-CoV inactivated vaccine.Methods:The virus suspension of F69 strain was inactivated with 0.4% formaldehyde and purified,then used as the immune antigen combined with Freund′s adjuvant.Eight adult New Zealand rabbits were immunized 4 times with this vaccine.12 sets of rabbit serum were sampled from the third day to 74th day after first immunization.Titers of specific IgG antibody and neutralizing antibody were determined by indirect ELISA and micro-cytopathic effect neutralizing test.Results:Rapid and potent humoral immune responses were induced by F69 inactivated vaccine in all eight immunized rabbits.Both specific IgG antibody and neutralizing antibody all peaked just with 2 vaccinations,with the maximum titer of 1∶81 920 and 1∶20 480 respectively about 6 weeks after first immunization.Across neutralizing reaction existed between F69 and Z2-Y3 strains.Conclusion:F69 inactivated vaccine owns strong immunogenicity.Similar antigenic epitopes exist between the F69 strain and Z2-Y3 strain,which ensured the cross neutralizing reaction.
3.Cerebral circulation characteristics of patients with persistent trigeminal artery combined with cerebrovascular diseases and their clinical relevance
Jianan WANG ; Xiongwei ZHANG ; Lei WANG ; Shimin YIN ; Bin DU ; Xianfeng LI
Chinese Journal of Neuromedicine 2014;13(3):277-281
Objective To explore the cerebral circulation characteristics of patients with persistent trigeminal artery (PTA) combined with cerebrovascular diseases and their clinical relevance.Methods Eight patients with PTA,admitted our hospital from March 2010 to March 2013 and conformed by DSA,MR radiography (MRA) or CT angiography (CTA),were chosen in our study; their cerebral circulation features and clinical manifestations were retrospectively analyzed.Results In these eight patients,two were combined with cerebral infarction,one with cerebral artery stenosis,two with cerebral infarction and cerebral artery stenosis,one with transient ischemic attack,and the left two with cerebral aneurysm.Four patients complained for paroxysmal dizziness (one of them with one-side weakness),two patients complained for numbness of a limb,One patient had headache and blepharoptosis and one patient had diplopia.Saltzman type Ⅰ was noted in six patients,type H in one and special type in one.The pathogenesis of cerebral infarction was related to PTA.Conclusion The clinical features of the patients with PTA often determine by merger cerebrovascular diseases; PTA can change the normal cerebral circulation; PTA detection can be helpful in the diagnosis of the pathogenesis of multiple cerebral infarction.