Objective: To observe the effects of needling Baihui (GV 20), Shuigou (GV 26) and Shenmen (HT 7) on cerebral glucose metabolism in patients with vascular dementia (VD) by cerebral functional imaging technique. Methods: Twenty-five patients with VD were divided into 5 groups (Group A, B, C, D and E) randomly. Patients in the Group A were treated by needling routine acupoints for hemiplegia (Acupoints of the three yang meridians of hand and foot), and besides the routine acupoints, patients in the Group B were treated by needling Baihui(GV 20), the Group C by Shuigou(GV 26), the Group D by Shenmen(HT 7), and the Group E by Baihui(GV 20), Shuigou(GV 26), and Shenmen(HT 7). All the patients were examined by Positron Emission Tomography (PET) to detect the cerebral glucose metabolism in the bilateral frontal lobes(orbital gyri), parietal lobes, temporal lobes(hippocampus and hippocampal gyrus), occipital lobes, thalamus, lentiform nucleus, caudate nuclei, cingulate gyms and cerebellum before treatments and after treatments. Results: After needling the routine acupoints for hemiplegia, glucose metabolism increased in lentiform nucleus and temporal lobe;needling Baihui(GV 20), increased in frontal lobe, temporal lobe and lentiform nucleus;needling Shuigou(GV 26), increased in frontal lobe, thalamus and lentiform nucleus; needling Shenmen(HT 7), increased in parietal lobe and lentiform nucleus; and needling these three acupoints, increased in frontal lobe, temporal lobe, thalamus and lentiform nucleus. Conclusion:Needling Baihui(GV 20), Shuigou(GV 26) and Shenmen(HT 7) affect glucose metabolism in different functional regions of the brain, and Baihui(GV 20), Shuigou(GV26) and Shenmen(HT 7) relate to different functional regions of the brain.

As an important landmark, the posterolateral wall of maxillary sinus can help to locate numbers of significant signs such as maxillary artery and its branches, maxillary nerve and infraorbital nerve, infratemporal fossa and pterygopalatine fossa etc. in the endoscopic surgery for paranasal sinuses and lateral skull base. This article reviewed related researches about the anatomy and endoscopic surgery of posterolateral wall of maxillary sinus.
Endoscopy ; Humans ; Maxillary Artery ; Maxillary Nerve ; Maxillary Sinus ; anatomy & histology ; Nasal Surgical Procedures ; Pterygopalatine Fossa

[Objective]To observe the cerebral activating effects of needling in Yanglingquan(GB34) vs a sham point of healthy volunteers based on the technique of fMRI.[Methods]Sixteen healthy volunteers were randomly divided into GB34 group and sham point group,and received needling in the different points on the right side respectfully.Super nuclear magnetic resonance(1.5T,GE Co.) was used to scan the brain and the obtained experimental data of the regional brain were processed and analyzed by method of Region of Interest(ROI).[Results]There was not any difference between needling in GB34 and the sham point in the cerebral activating rate.While the activating number of needling in the sham point was more than that of needling in GB34 in bilateral parietal lobes and right occipital lobe(P

Objective To evaluate the unusual echocardiographic manifestation and its clinical value in the patients with constrictive pericarditis (CP). Methods To analyse the echocardiographic manifestation of CP in 187 patients retrospectively, especially left ventricular ejection fraction (LVEF) and variation with respiration (VER) in mitral E velocity. Results Most of the patients with CP expressed the common echocardiographic features of CP. But some unusual echocardiographic signs were revealed. (1)LVEF

Objective To improve the understanding of cardiac valve involvement in Behcet's disease (BD).Methods The echocardiographic manifestations of 13 patients with BD were analysed and the results of 5 patients were compared with those of operation.Results Cardiac valve involvement wasn't rare.In the study,cardiac valve involvement was observed in 26% (13/50) of patients with BD.The principal manifestations of cardiac valve involvement were valve prolapse,perforation,split and regurgitation.Four (80%) patients had repeated operation.Conclusion Echocardiography provides the important information of valvular morphology and function in BD.

Objective To determine the effect of caspase 9 in the apoptosis of hepatoma cells induced by flurouracil , and to investigate the activity alteration and proteolytic cleavage of caspase 9. Methods The human hepatoma HepG2 cells were treated with flurouracil for 2,4,8,16,24h respectively. The caspase 9 activity was detected using caspase 9 Fluorescent Assay Kit.Proteolytic cleavage of caspase 9 was analyzed by Western blot.The apoptotic rates of HepG2 cells induced by flurouracil with or without caspase 9 inhibitor treatment were measured by flow cytometry. Results Four hours after being treated with flurouracil, the caspase 9 activity in HepG2 cells increased gradually and reached the peak at 16h.Compared with the control group, the difference was significant (P

Objective To investigate low molecular weight heparin(LMWH) therapy for pancreatic encephalopathy in severe acute pancreatitis(SAP).Methods SD rats were randomly divided into 3 groups:(1) Sham operation(S) group,(2) SAP group and(3) LMWH treatment(LT) group:LMWH was administrated at 4 hours after construction of SAP model.The levels of serum amylase,myelin basic protein(MBP),tumor necrosis factor alpha(TNF-?),interleukin 6(IL-6),brain water contents and pathological changes of pancreas and brain were measured at 24 h after models were set up in SAP and in S group,and 24 h after LMWH was administrated in LT group.Results(1) The levels of serum amylase,TNF-?,IL-6 in SAP group were significantly higher than those in S group and LT group(all P 0.05).(2) The brain water content in SAP group was significantly higher than that in S group and LT group(P

Objective To investigate the protective efficiency of low molecular weight heparin (LMWH) on lung injury in severe acute pancreatitis (SAP).Methods SD rats were randomly divided into 3 groups:(1) Sham operation (S) group,(2) SAP group,(3) LMWH treatment (LT) group:LMWH was administrated 4 hours after SAP model was constructed.The levels of serum amylase,endothelin1(ET-1),tumor necrosis factor ? (TNF-?),lung wet/dry weight ratios,pulmonary morphology,the expressions of P65mRNA and P65 protein in pulmonary specimens were detected at 1d after the models were set up,and the 3 days survival rate in each group was also observed.Results (1) The levels of serum amylase,TNF-?,ET-1 in SAP group were significantly increased than those in S group and LT group (all P

Objective To investigate the effect of low molecular weight heparin (LMWH) on kidney injury in severe acute pancreatitis (SAP). Methods SD rats were randomly divided into 3 groups: Sham operation (S) group,SAP group, and LMWH treatment (LT) group. In LT group LMWH was administrated 4 hours after SAP model establishment. The levels of serum amylase, creatinine (Cr) and tumor necrosis factor alpha (TNF-?), renal morphological change, and the expression of p65 mRNA and protein in renal specimens were determined 24 hours after model establishment or LMWH treatment. Results The levels of serum amylase,Cr,TNF-? in SAP group were significantly higher than those in S group and LT group (all P0.05). The expression of p65 protein and mRNA of renal tissues in SAP group was significantly higher than that in S group and LT group (all P

Objective To explore the action mechanism of shenxiong glucose injection in treatment of acute spinal cord injury(SCI) through observing its effects on the recovery of motor function and the expression of aquaporin-4(AQP-4) in SCI rats.Methods Totally 90 healthy,aduh,Sprague-Dawley rats were randomly divided into a sham operation group (n=30),aSCI group (n=30) and a drug group (n=30).The SCI rat models in both the SCI group and the drup group were established aecording to the modified Allen's method,while the sham operation group was only given laminectomy.After the operation,the drug group was given intraperitoneal shenxiong glucose injection of 30 rnl/kg a day,while the other two groups were injected in the same way with normal saline.The neural function recovery,the pathological changes after SCI and the expressions of AQP-4 were observed 1,3,7,14 and 21 d after the operation using the Tarlov score,the hematoxylin and eosin staining,as well as immunofluorescence techniques and Western blotting.And the correlation of Tarlov scores with AQP-4 expressions was analyzed.Results No significant changes in Tarlov scores were observed in the sham operation group (P ＞ 0.05),while in the SCI group and the drug group,postoperative Tarlov scores decreased significantly.The hindlimb nerve function recovered to some degree with time in the SCI group and drug group.At 3,7,14 and 21 days after the operation,the Tarlov scores in the drug group were significantly higher than the SCI group (P ＜ 0.05).The drug group showed less severe pathological changes,with more residual neurons still visible of nucleoli than the SCI group 21 days after the operation.Compared with the sham operation group,the expression levels of AQP-4 were significantly higher in the SCI group and drug group at all the time points (P ＜ 0.05).However,the expression levels of AQP-4 in the drug group were significantly lower than the SCI group accordingly (P ＜ 0.05).The Tarlov scores were found to be significantly and negatively related to the AQP-4 protein expression levels 3 days(r =-0.523,P =0.003),7 days(r =-0.437,P=0.016),14 days(r=-0.417,P=0.022) and 21 days(r=-0.377,P=0.040)after the operation.Conclusion Injecting shenxiong with glucose can effectively promote the recovery of motor function after SCI,at least in rats.And its mechanism may be that the development of spinal cord edema is prevented and the secondary spinal cord injury alleviated by restraining the expressions of AQ P-4 in the injured areas.