1.Classification and Pathological Analysis of Immunophenotype of 76 Cases of Non-Hodgkin Lymphoma in Shenyang
Huiying HE ; Xinshan JIA ; Yi GUO
Journal of China Medical University 2001;30(1):1-3
Objective: Our aim was to discuss the pathological characteristics and immunophenotype of non-Hodgkin lymphoma (NHL) in Shenyang. Methods: Histopathological observation was performed with immunohistochemical methods (SP method). We used 10 antibodies as B,T markers to analyze 76 cases of NHL according to the new WHO classification. Results: The B-NHL was more prevalent than the T-NHL. In B-NHL, the Diffuse Large B cell Lymphoma (DLBL) was the most common, next was the mucosa-associated lymphoid tissue lymphoma (+/-monocytoid B-cells) and lymphoplasmacytic lymphoma (LPL). In T-NHL, the peripheral T cell lymphoma unspecificly accounted most. The positivity rates of CD79a in B-NHL were 100% and its cross-reactivity was 0. The straining rates of polyclonal CD3 with T cell were 88% and CD3 only reacted with 5% of B-NHL. Conclusion: The NHL in Shenyang was marked by the most common DLBL and peripheral T cell lymphoma, unspecificly. The rates of monocytoid lymphoma and LPL were higher. The CD79a and CD3 were antibodies of B-cell and T-cell markers with high sensitivity and specificity, respectively.
2.The various links of the university talent introduction
Zibao GUO ; Jianying LIU ; Xinshan CHEN
Chinese Journal of Medical Education Research 2006;0(07):-
Talent introduction is of great significance for the development of universities and for the raising of the academic standards.Talent introduction in general includes three links,namely,planning,the policy supporting and the concrete implementation.In the supporting policies of the talent introduction various relations should be properly handled,such as the new talents and the old talents relations,the relationship between the introduction and cultivation and the relationship between the high-level personnel and the conventional talents.
3.Correlation Between Deep Brain White Matter Ischemia and MR Diffusion Tensor Imaging of Mild Cognitive Impairment
Licun LEI ; Yaqiang DU ; Li HE ; Weixiu WANG ; Yanhua WU ; Xinshan GUO
Chinese Journal of Medical Imaging 2013;(10):737-740
Purpose To investigate the correlation between the brain white matter changes of MR diffusion tensor imaging (DTI) and cognitive function in the patients with mild cognitive impairment. Materials and Methods The patients (40 cases) were classified into two groups:group A (20 patients with ischemic foci in the deep white matter ) and group B (20 patients without ischemic foci in the deep white matter), and 20 normal controls was enrolled. Conventional MRI, DTI, mini-mental state examination (MMSE) and montreal cognitive assessment (MoCA) were applied, then fractional anisotropy (FA) value and apparent diffusion coefficient (ADC) value were compared among three groups. The scores of MoCA was analyzed between the patient groups. Results The decreased FA value, increased ADC value and decreased MoCA scores was demonstrate in group A, and showed significant difference compared with group B (t=-4.229,-3.251,-7.533,-2.702,-2.660;P<0.05). The increased ADC value and decreased FA value in the frontal and hippocampus region were detected in group B compared with normal controls (t=-7.790,-2.785,-4.415,-5.164;P<0.05). Conclusion The early and special structural changes can be detected using DTI compared with conventional MRI. The severe white matter lesions can be demonstrated in the patients with ischemic foci in the deep white matter, who is prone to dementia.