OBJECTIVE:To evaluate the therapeutic effects and cost-effectiveness of 3 therapeutic regimens in the treatment of vertebrobasilar ischemia. METHODS: 90 cases with vertebrobasilar ischemia were randomly divided into 3 groups: Group A were assigned to receive buflomedil+Flunarizine, Group B to receive Shuxuening + Flunarizine and Group C to receive compound Compound Danshen + Flunarizine. The curative effects and the cost-effectiveness of the 3 Groups after 14-day treatment were analyzed comparatively. RESULTS: The total costs for Group A, B and C were 1 705.06 yuan,2 876.30 yuan and 1 117.34 yuan, respectively; the effective rates were 93.75%, 92.86% and 70.00%, respectively; the cost-effectiveness ratios were 1 818.73, 3 097.46 and 1 596.20, respectively. As compared with Group C, the incremental costs-effectiveness ratios for Group A and Group B were 2 474.61 and 7 694.49, respectively. CONCLUSION: Group A is more preferable among the 3 therapeutic regimens in terms of cost-effectiveness.

OBJECTIVE:To discuss the problem in Chinese Traditional Medicine market and provide some countermeasures for its supervision. METHODS: We analyzed the status quo of Chinese traditional medicine market and the reasons accountable for the problem existing in Chinese traditional medicine market. RESULTS & CONCLUSION: The quality of Chinese traditional medicine and Chinese medicinal decoction pieces in Chinese traditional medicine market is far from perfect, it is urgent to tighten supervision on the quality of Chinese traditional medicine.

OBJECTIVE:To study the compatible stability of ornidazole sodium chloride injection with latamoxef disodium.METHODS:Content changes of the mixed solution of ornidazole sodium chloride injection with latamoxef disodium were detected at different time by ultraviolet spectrophotometry;and the pH value,the appearance and the insoluble microparticles of the solution were also detected.RESULTS:Storing for 8 hours under room temperature,the combined solution looked clear,no significant change was noted regarding the content of ornidazole,but a slight reduction was noted regarding the content of lata_moxef disodium and the pH value had a slight change.CONCLUSION:Ornidazole sodium chloride injection and latamoxef dis_odium can be administered compatibly.

In China, the implementation of community health service shows that the prevention is an essential and important part of our national health system and is helpful to decrease the medical expenditure gradually. According to the data from Health Statistic Information Center of Ministry of Health in China, we calculated that the total health expenditure of China would be decreased 8000.0 million yuan only in 2001, among which, 1188.3 million, 1953.9 million and 4833.0 million yuan were respectively saved for the government budget, the society and resident if implementing the policy of community health service powerfully. And every outpatient can save 15.46 yuan per time. By the quantitative analysis on the economic contribution of community health service, it can be proved that a great economic benefit could be gotten from the implementation of community health service.
China ; Community Health Services/*economics ; Financing, Government ; Health Care Costs ; *Health Expenditures ; Health Plan Implementation/economics

This paper discussed the characteristics,contents and implementation of quality education of medical students during basic education.

0.05), higher than those in the nighttime (t=3.63,3.16;P

Objective　To study the changes of quantitative expression,adhering activity and genomic density polymorphism of complement type 1 in erythrocytes (CR1) of patients with liver cancer (104 patients) and their clinical significance.Methods　Polymerase chain reaction (PCR),HindIII restriction enzyme digestion,the quantitative assay of ECR1 and the adhering activity assay of CR1 in erythrocytes were used.Results　No difference was observed between the patients with liver cancer (29.8%) and healthy individuals (25.3%) in the spot mutation rate of CR1 density gene (χ2 =0.537,P>0.05).The number and the adhering activity of CR1 in patients with liver cancer (0.83±0.22 and 47.1±6.5) were significantly lower than those in healthy individuals (1.26±0.33 and 62.4±7.6; t=10.5,P<0.0001).The number and the adhering activity of ECR1 in high expression genomic type (HH) liver cancer were obviously lower than those of healthy individuals,expecially those of the patients with advanced liver cancer.There was a good relationship between quantitative expression,adhering activity of ECR1 and liver cancer development.Conclusion　Defective expression of CR1 in liver cancer is mostly acquired through central peripheral mechanisms.The changes of CR1 quantitative expression and adhering activity are consanguineously related to the severity and the activity of the development in patients with liver cancer.

Objective To investigate the influence of the core-veneer interfacial surface roughness on the flexural strength and failure mode of bilayered lithium-disilicate ceramic structure.Methods Forty IPS e.max Press bar-shaped specimens were fabricated and divided randomly into 4 groups.The core-veneer interfacial surfaces of the core materials were ground to specific surface roughness with silicon carbide papers of various grits.Specimens of the groups A,B and C were ground by silicon carbide papers of 1000 grits,600 grits and 320 grits,respectively.While specimens in group D were sandblasted without any grinding as recommended by the manufacturer's instruction.After veneer application and sintering,the flexural strength of bilayered specimens were measured utilizing three-point bending test,and the failure mode was observed using stereomicroscopy.Results The mean flexural strength value of bilayered specimens for groups A,B,C and D were (164.27±15.02),(159.21± 15.72),(156.14±17.10) and (152.97±15.61) MPa,respectively.However,there was no significant differences in fracture strength between groups (P＞0.05).All specimens demonstrated cohesive failure of veneer porcelain right underneath the indenter,without any core-veneer delamination.Conclusions The influence of core-veneer interfacial surface roughness on flexural strength of bilayer lithium-disilicate-based ceramics is not significant.The superior bond between core and veneer provides a reliable interface.

Objective To investigate the correlation between prognosis of patients with severe acute pancreatitis and changes of plasma albumin. Methods A total of 235 patients with severe pancreatitis who were admitted into hospital from September 2008 to October 2013 were selected as research object. According to the prognosis, they were divided into the survival group (143 cases who were recovered and still alive) and the death group (92 cases who died of the deterioration of diseases). Retrospectively analyzed the basic situation of the pa-tients and the changes of serum albumin levels in the two groups. And the correlation between prognosis of patients with severe acute pancrea-titis and changes of plasma albumin were evaluated by the logistic regression analysis. Results Compared with the death group,there were significant differences (P<0. 05) in terms of age,APCHEⅡ score,Ranson score,SOFA score,length of hospital stay,duration of mechani-cal ventilation,continuous renal replacement therapy,average serum albumin level,decrease of serum albumin within 24 hours,and variation of serum albumin. And ROC curves suggested the best cutoff value of decrease of serum albumin within 24 hours to predict death in patients within 24 hours was 4. 24 g/L,and the best cutoff value of variation of serum albumin to predict death was 13. 6%. Logistic regression analy-sis showed that the major risk factors of death in severe acute pancreatitis were decrease of serum albumin within 24 hours,variation of serum albumin within 24 hours,average serum albumin level,and the APCHEⅡscore. Conclusion Changes in plasma albumin can reflect the se-verity of severe acute pancreatitis,and the sharp decrease of serum albumin within 24 hours can be used as a risk factor for death.

Plasmodium yoelii yoelii-Anopheles stephensi system was chosen as the experimental model in studying the effects of pyrimethamine on oocyst formation of the plasmodium species. The drug was given by allowing mosquitoes to feed on infected and pyrimethamine treated mice or by feeding them directly with pyrimcthamine-sugar water. The infective rate and the number of oocysts formed after drug administration were reduced, the oocysts formed being smaller and their daily growth rate slower than that of the controls. Electron microscopic and Feulgen staining studies showed that the cytoplasm of the affected oocysts contained many vacuoles, pigment aggregations and black aggre-gates (Fig. 4). No nucleus appeared in the affected oocysts, which were presumably deteriorated and became "black spores". The amount of DNA in drug-affected oocysts was scanty. No sporozoites were found in the salivary glands of these mosquitoes. It was suggested that pyrimethamine interfered with DNA synthesis of oocysts.