1.Application of two-way shrinking field radiotherapy with high intensity in non-small cell lung cancer with stage Ⅳ
Quankui LI ; Xingxiu CHEN ; Mei XU
Clinical Medicine of China 2015;31(5):426-428
Objective To investigate the advantage of two-way shrinking field radiotherapy with high intensity on non-small cell lung cancer(NSCLC) with stage Ⅳ.Methods Forty-two old NSCLC patients with stage Ⅳ were selected as our subjects who cannot performed surgery in the People's Hospital of binzhou.The patients all underwent CT-scan and the CT information was input TPS planning system in order to outlined gross tumor volume(GTV1) and make plan 1 with the first three-dimensional conformal radiotherapy 50 Gy/25 F~ 54 Gy/27 F.Then the 2nd CT-scan was performed to sketch GTV2 and make Plan 2.The detail of Plan 2 was that the amount of radiation was increased to the total 66 Gy/33 F ~ 70 Gy/35 F,two radiotherapy plans in accordance with 1 times/d,5 times/weeks;chemotherapy with paclitaxel 40 mg/m2,weekly radiotherapy before the intravenous infusion,once every 6 weeks.Results The median of reduce tumor size between GTV2 and GTV1 was 68.85 cm3 and relative reduce tumor size was 28.32%.As to short-term effect,there were 5 cases with total recovery(1 1.9%),25 cases with partly recovery(59.5%),10 cases with stable stage (23.8 %),2 cases with development(4.8%).Local control rate regarding of tumor development was 71.4% at 1-yrea period and 23.8% at 2-year periods.Survival rate was 73.8%(31/42) at 1 year and 28.6%(12/42) at 2-year.Side effects included radiation esophagitis and radiation pneumonitis based,radiation-induced lung injury.Condusion The therapy scheme of two-way three-dimensional conformal radiation dosage treatment of NSCLC,GTV and re-plan outlined dosage can increase the target dose,radiation therapy to reduce side effects.
2.Effect of combination of partial body weight support and functional electrical stimulation on lower limb motor function after stroke
Xingxiu XIONG ; Zhenghui ZHANG ; Chunyan DENG ; Yunbo LI ; Zhenpeng CHEN ; Yuanjie LI ; Jing SONG
Chinese Journal of Rehabilitation Theory and Practice 2024;30(5):554-559
ObjectiveTo observe the effect of combination of partial body weight support and functional electrical stimulation on lower limb motor function for stroke patients. MethodsFrom January, 2023 to February, 2024, 60 stroke patients from Rehabilitation Hospital of Chancheng District People's Hospital in Foshan City were randomly divided into control group (n = 30) and observation group (n = 30). The control group received routine rehabilitation, while the observation group received a combination of celestial orbit system and functional electrical stimulation in addition, for three weeks. They were assessed with Balance assessment and training system, Berg Balance Scale (BBS), Fugl-Meyer Assessment-Lower Extremities (FMA-LE) and Holden Functional Ambulation Category (FAC) before and after treatment. ResultsX-axis trajectory length, average speed of swaying, total wobble trajectory, Y-axis trajectory length, trajectory length per unit area, BBS score, FMA-LE score and FAC score improved in both groups after treatment (|t| > 4.809, P < 0.001); and all the indexes improved more in the observation group than in the control group (|t| > 2.268, P < 0.05), except X-axis trajectory length and average speed of swaying. ConclusionSupplement of the combination of partial body weight support and functional electrical stimulation is more effective on lower limb motor function, balance and walking for stroke patients.