Objective To analyze the multislice CT (MSCT) imaging performance of various kinds of thymic lesions and to explore useful signs for differentiating those lesions.Methods CT features of 39 cases with thymic lesions confirmed by operation and pathology were reviewed retrospectively analyzed and these cases were divided into three groups,namely low-risk group,high-risk group,cancer and carcinoid group.The imaging characteristics of each group including location,size,shape,border,density,invasion and metastasis,degree of enhancement were compared and the main different characteristics among the three groups were analyzed.Results Among the 39 cases,21 were low-risk,13 were high-risk and 5 were cancer and carcinoid.There were significant difference among the three groups in shape,border,density,invasion and metastasis of these thymic lesions on CT imaging (P ＜ 0.05).As for the irregular shape and nonuniform density,there were 5 and 4 cases in cancer and carcinoid group and only 1 and 3 cases in low-risk group,the difference between the two groups were statistically significant(P ＜ 0.05).As for invasion and metastasis,there were no statistical significant between the high-risk group and the cancer and carcinoid group,but both had statistical significant with the low-risk group respectively (P ＜ 0.05).No significant difference existed among the three groups in size and degree of enhancement(P ＞ 0.05).Conclusion MSCT might be an effective and important imaging tool for differentiating various kinds of thymic lesions.

0.05), but LA patients had less postoperative pain,less time to ambulation after operation, less time to food intake after operation, less average length of hospital stay,less rate of incision infection and less intestinal adhesion than OA did(all P

OBJECTIVE: To investigate the effects of Xiehuo Bushen Decoction (XHBSD), a compound Chinese herbal medicine, on the survival and differentiation of transplanted neural stem cells (NSCs) in brains of rats with intracerebral hemorrhage, and to explore the mechanism of Xiehuo Bushen formula in promoting the survival of transplanted NSCs. METHODS: NSCs separated from hippocampuses of neonatal SD rats were cultured. Sixty-five panel reactive antibody (PRA) positive SD rats were selected by lymphocytotoxicity methods. The PRA positive rats were made into intracerebral hemorrhagic model and divided into three groups: cerebral hemorrhage group (n=15), NSCs transplanted group (n=25) and XHBSD group (n=25). XHBSD was orally administered after 5-bromodeoxyuridine (BrdU)-marked NSCs were transplanted in brains of rats with intracerebral hemorrhage in the XHBSD group. Rats in the other two groups were administered distilled water. The expressions of interferon gamma (IFN-gamma) and interleukin-4 (IL-4) mRNAs were measured by reverse transcription polymerase chain reaction (RT-PCR); the numbers of BrdU and 200 kD neurofilament (NF200) positive cells were detected by double-labeling immunofluorescence method. RESULTS: The expression of IFN-gamma mRNA was down-regulated significantly in the XHBSD group, but the expression of IL-4 mRNA was up-regulated significantly (P<0.05). The numbers of BrdU and NF200 positive cells were also increased remarkably in the XHBSD group. CONCLUSION: XHBSD can promote the survival and differentiation of transplanted NSCs, which may be related to inducing the expression of IL-4 mRNA and inhibiting the expression of IFN-gamma mRNA.