1.A case of melanotic neuroectodermal tumor of infancy and review of literature
Jingjing MAO ; Xingqiao XU ; Yanliang WANG ; Zhihui ZHOU ; Miaojie LANG
Journal of Practical Stomatology 2015;(4):584-587
This paper reports a case of melanotic neuroectodermal tumor of infancy (MNTI)arising in the maxilla of a 3-month-old male infant.The treatment included surgical excision of the lesion with safe margin,curettage of the maxilla and removal of associated developing tooth bud.Microscopically,it proved to be a dual tumor with small,neuroblastic-like cells and larger epithelial cells.Immunohistochemical staining demonstrated epitheloid cells HMB45(+),EMA(+),CK(+);neuroblast-like cells NSE(+),GFAP(+),S-100(+),but both cells Vim(+),CD45(-),Myogenin(-).The 18-mouth follow-up showed no recurrence or metastasis.The related literature was re-viewed.
2.Comparison of the efficacy of pantoprazole and omeprazole in the treatment of elderly patients with peptic ulcer
Rongcheng XU ; Xingqiao YANG ; Dongni WU ; Xia YE
Chinese Journal of Primary Medicine and Pharmacy 2017;24(9):1373-1377
Objective To compare the clinical effect of pantoprazole and omeprazole in the treatment of elderly patients with peptic ulcer.Methods 200 patients with peptic ulcer were selected as study subjects,and they were randomly divided into two groups.The control group (100 cases) was orally given clarithromycin,amoxicillin and omeprazole triple therapy.The observation group (100 cases) was given clarithromycin,amoxicillin and pantoprazole triple therapy.The clinical efficacy,clinical symptoms disappeared time and adverse reactions occurred in the two groups were compared.Results The total effective rate of the observation group was 96%,which of the control group was 94%,the difference between two groups was not significant (x2 =0.421,P > 0.05).The disappear time of abdominal pain,belching,burning and bleeding in the observation group after treatment were significantly shorter than those of the control group(t =35.545,56.680,98.896,61.109,all P < 0.05).The incidence rate of adverse reaction of the observation group(5.0%) had no significant difference compared with the control group(7.0%) (x2 =0.354,P > 0.05).Conclusion There is no significant difference in efficacy and safety between pantoprazole and omeprazole in the treatment of elderly patients with peptic ulcer,but the effect of pantoprazole on relieving symptoms is better than omeprazole.