1.A STUDY ON THE CONTENT OF NUTRIENTS IN ROSE ROXBURGHII TRATT FRUIT
Zhaofan HE ; Luyun XIONG ; Xingmin GUO ; Aizhen NIU
Acta Nutrimenta Sinica 1956;0(03):-
Results obtained from current studies showed that the vitamin C (VC) content in Rose roxburghii Tratt was higher, about 1664-2601 mg/100g fresh sample, than all the fruits and vagetables. Vitamin E(VE) ranged from 2.4 to 3.6mg/100g sample was also higher than any other fruits and vegetables.After the wild plants were domestricated for 2 years, its VC content increased about 26%, Sugar increased 50%, tannin, however, decreased approximately 50%.
2.Interaction between obesity/central obesity and hypertension
Liangliang WANG ; Yu HUANG ; Wei GUO ; Xingmin WEI ; Ning FAN ; Guixue ZHAO ; Yahui XIE ; Dongjing MA ; Yunchao WANG ; Xinhua WANG ; Jianjun WU
Journal of Preventive Medicine 2022;34(2):129-134
Objective:
To examine the effects of obesity and central obesity on hypertension, so as to provide insights into the prevention and control measures of hypertension.
Methods:
From September to December 2018, residents at ages of 35 to 75 years were sampled using the multi-stage random sampling method in Baiyin District, Baiyin City, Gansu Province, and subjected to questionnaire surveys and physical examinations. The interaction between obesity/central obesity and hypertension was evaluated using logistic regression analysis. The synergy index ( SI ), relative excess risk due to interaction ( RERI ) and attributable proportion due to interaction ( AP ) were calculated using Excel compiled by Andersson et al.
Results:
A total of 6 246 questionnaires were allocated and 6 169 valid questionnaires were recovered, with an effective recovery rate of 98.77%. The respondents included 3 038 men ( 49.25% ) and 3 131 women (50.75%), with a mean age of ( 52.05±8.78 ) years. There were 832 respondents with obesity ( 13.49% ) and 2 278 with central obesity ( 36.93% ). The crude and standardized prevalence rates of hypertension were 35.89% and 33.05%, respectively. Multivariable logistic regression analysis showed that obesity ( OR=2.020, 95%CI: 1.705-2.393 ) and central obesity ( OR=1.622, 95%CI: 1.433-1.836 ) were statistically associated with hypertension. There was no multiplicative interaction between obesity or central obesity and hypertension ( OR=1.011, 95%CI: 0.655-1.560 ), and no additive interaction was detected between obesity or central obesityand hypertension ( SI=1.405, 95%CI: 0.815-2.424; RERI=0.658, 95%CI: -0.298 to 1.614; AP=0.201, 95%CI: -0.075 to 0.476 ).
Conclusions
Obesity and central obesity increase the risk of hypertension; however, no interaction is detected between obesity or central obesity and hypertension.
3.Imaging study of β-amyloid deposits in preclinical Alzheimer′s disease patients in communities of Shanghai
Mengjie WANG ; Shasha XU ; Donglang JIANG ; Junpeng LI ; Jianfei XIAO ; Shuhua REN ; Qi HUANG ; Yihui GUAN ; Xingmin HAN ; Lin HUANG ; Keliang CHEN ; Fang XIE ; Qihao GUO
Chinese Journal of Nuclear Medicine and Molecular Imaging 2023;43(1):20-24
Objective:To explore the β-amyloid (Aβ) deposition pattern of subjects with the preclinical Alzheimer′s disease (AD), community-derived amnestic mild cognitive impairment (aMCI) and normal cognition (NC) from communities of Shanghai.Methods:According to the inclusion and exclusion criteria, 273 subjects (104 males, 169 females; age (64.2±7.6) years) were recruited from Shanghai community and memory clinics from December 2018 to July 2020. All subjects underwent MRI, 18F-AV45 PET imaging and neuropsychological scale tests and were grouped into AD, aMCI and NC groups based on clinical diagnosis. Differences in demographic information, the neuropsychological scale tests′ scores and positive rate of Aβ deposition among each group were analyzed by one-way analysis of variance or χ2 test. Aβ deposition patterns of AD and MCI groups were analyzed at voxel level, and the differences of Aβ deposition among different groups were compared. Results:Among 273 patients, the positive rates of Aβ deposition in AD, aMCI and NC groups were 84.4%(38/45), 36.4%(20/55) and 23.1%(40/173), respectively ( χ2=58.37, P<0.001). Among AD, aMCI, NC and NC (Aβ-) groups ( n=132), the education years of AD group was the lowest ((9.7±4.6) years; F=8.86, P<0.001). In addition, there were significant differences in the scores of several neuropsychological scale tests among AD, aMCI, NC groups and NC (Aβ-) group ( F values: 27.68-235.50, all P<0.001). Compared with subjects in NC(Aβ-) group, the Aβ depositions in the aMCI and AD groups were widely distributed in the whole cerebral cortex; and AD group had higher Aβ deposition in bilateral frontal, parietal, temporal, occipital lobe, cingulate gyrus and precuneus than aMCI group. Conclusions:The positive rate of Aβ deposition in the preclinical AD population from the Shanghai community is obtained. There are significant different Aβ deposition patterns in subjects at different stages of AD.