1.Exposure Treatment of Posttraumatic Stress Disorder
Chinese Journal of Clinical Psychology 2000;0(04):-
Earthquakes affect numerous people,among whom many may develop PTSD.Therefore,easily disseminated and effective psychological interventions are urgently needed.The clinical practice guidelines developed by the International Society for Traumatic Stress Studies suggested that exposure therapy was the most empirically supported treatment for PTSD.The present study introduced Behavioral models of Posttraumatic Stress Disorder,major process of Exposure treatment for PTSD and relative problems.Compared with other treatments for PTSD,the theory models and techniques of Exposure treatment of PTSD are easier and readily lend themselves to dissemination.Considering serious situation now and in the future after this earthquake in Sichuan,clinical professionals should pay attention to exposure treatment of PTSD.
2.Patterns of Attentional Bias of Highly Anxious Individuals by Repeating the Occasions of Word Stimulus
Chinese Mental Health Journal 2002;0(11):-
Objective:This study aimed to investigate the pattern of anxiety-related attentional bias for threaten- ing words in subjects with high-and low-trait anxiety by repeating the occasions of stimulus exposures.Methods:High (upper 25%)and low(lower 25%)anxious individuals(N=24 and N=23 respectively)participated in a forced- choice reaction time version of a modified dot-probe task.There were 48 negative-neutral word pairs chosen as stimuli. Each word pairs were presented eight occasions in different blocks,and at each occasion the attentional bias to the e- motionally negative word was examined.Results:High anxious individuals showed initial selective attention to the neg- ative words when they were presented for the first occasion(t=2.34,P
3.Treatment of Hoffa fractures
Chinese Journal of Orthopaedic Trauma 2011;13(7):620-625
Objective To investigate clinical characteristics and treatment of Hoffa fractures.Methods Twenty patients with Hoffa fracture (24 condyles) were treated from January 2002 to April 2009.They were 14 men (18 condyles) and 6 women (6 condyles), aged from 20 to 70 years (average, 43. 3 years).There were 15 fractures of medial femoral condyle and 9 ones of lateral femoral condyle. Two rare cases were fractures of unilateral bi-condyles and one rare case fractures of unilateral bi-condyles plus contralateral single condyle. Four fractured condyles were old due to implant failure and 20 were fresh. According to the modified Letenneur's classification, there were 6 condyles of type Ⅰ, 4 condyles of type Ⅱ and 14 condyles of type Ⅲ.Fifteen condyles were fixed anteroposteriorly with 2 to 4 cancellous or canulated screws, 8 condyles were fixed posteroanteriorly with 2 to 4 screws, and one condyle was fixed with K wires. Five condyles were fixed with screws plus lateral supporting plates, and 3 condyles with screws plus posterior anti-sliding plates. Results All the patients were followed up for an average of 14. 4 months (6 to 84 months) . All the 24 condyles obtained bony union after an average of 18. 6 weeks (from 12 to 44 weeks). There was no infection, implant failure, nonunion or bone necrosis. According to Letenneur's functional assessment system, 16 condyles were excellent, 6 good and 2 poor, with a good-to-excellent rate of 91. 7%. Conclusions All Hoffa fractures should be treated with screws. Screw diameter, fixation direction and surgical incision should depend on facture type and size of fracture block. Unstable Hoffa fractures should be treated with screws combined with lateral supporting plates or posterior anti-sliding plates.
4.Effect of povidone iodine irrigation combined with levofloxacin eye drops on inflammatory indexes, NO and antioxidant indexes in serum and tear fluid of patients with diabetic cataract
Chinese Journal of Biochemical Pharmaceutics 2015;37(7):125-127
Objective To investigate the effect of povidone iodine irrigation combined with levofloxacin eye drops on the inflammatory indexes, NO and antioxidant indices in serum and tear fluid of patients with diabetic cataract.Methods 50 cases of pati ents with diabetic cataract and admitted into the hospital during January 2013 to January 2015 were selected as the research objects all of whom received cataract surgery.According to the randomized double blind method, the patients were divided into two groups with 20 cases in each group.The control group received levofloxacin eye drops intervention before surgery while the observation group were treated withpovidone iodine irrigation, based on the control group.The inflammatory indexes (IL-2, sIL-2R, IL-6), NO, antioxidant indexes (TAC, SOD, CAT) and condition of postoperative infection were compared between the two groups before and after irrigation.ResuIts In the observation group, the sIL-2R, IL-6 and NO levels in serum and tear fluid after irrigation were significantly lower than those in the control group while IL-2, TAC, SOD and CAT were significantly higher than those in the control group.The differences were statistically significant (P<0.05).The postoperative infection rate of the observation group was 0.0% which was significantly lower than 16.0% of the control group.The difference was statistically significant ( P<0.05 ) .ConcIusion Povidone iodine irrigation combined with levofloxacin eye drops can significantly reduce the inflammatory reactions in patients with diabetic cataract and improve their antioxidant level.
5.Progress in research on acceptance strategy coping with chronic pain
Chinese Journal of Behavioral Medicine and Brain Science 2015;24(8):756-759
Objective Chronic pain has brought great suffering to patients,as well as a heavy burden to the society.More attention has been paid on the efficiency of psychological intervention as supplementary means.Among the treatments,acceptance strategy shows its superiority and gradually enters people's field of vision.However,researches in this area are still very scarce.This study intends to review relevant research to provide reference to clinical work and research.Methods Theacceptance andchronic pain as the keywords were searched from the American Psychological Association (APA),China National Knowledge Infrastructure (CNKI),Wanfang data from 1994 to 2014 in English and Chinese articles,and the articles were chosen according to the criteria:① chronic pain and its current situation;②acceptance strategy or acceptance-based therapy;③intervention to chronic pain based on acceptance strategy;④to explore the intervention mechanism of aueptance strategy.Results Eventually,7 Chinese articles and 42 English articles were adopted.Conclusion Acceptance strategy shows some advantages in clinical pain improvement:it can significantly improve the psychological and social function of patients,but it is not always efficient in reducing the pain intensity.There are still some limitations in the present study.It is necessary to develop an acceptance-based therapy with Chinese culture to treat the domestic patients.
6.Exposure and Ritual Prevention of Obsessive-compulsive Disorder:A Case Study
Chinese Journal of Clinical Psychology 1993;0(02):-
Objective:To investigate effectiveness of exposure and ritual prevention of patients with obsession-compul-sive disorder(OCD),so as to provide references for professionals in clinical psychology.Methods:One female patient with severe OCD received 3 weeks intensive exposure and ritual prevention treatment.In order to investigate the effectiveness,she completed Symptom Check List 90 and Yale Brown Obsessive Compulsive Scale(SCL-90 and YBOCS) at pre-treat-ment,mid-treatment and post-treatment.Results:After treatment,the patient's scores of questionnaires reduced,such as score on YBOCS reduced from 38 to 9.She reported that her washing time reduced obviously and her own measure of dis-tress index reduced.Conclusion:Exposure and ritual prevention could treat the patient with OCD effectively.Her distress reduced and life function was improved.
7.Stem cell transplantation for inflammatory bowel diseases
Qingqing LI ; Jiankun LIU ; Xinghua PAN
Chinese Journal of Tissue Engineering Research 2017;21(21):3432-3437
BACKGROUND:Stem cell transplantation can, in theory, rebuild the immune system and regulate immunologic function. In addition, the transplanted stem cells may differentiate into tissues or cells we want. Therefore, this intervention may restore gastrointestinal inflammatory lesion and exert therapeutic effect on inflammatory bowel diseases (IBD). OBJECTIVE:To review the application of different kinds of stem cells in IBD treatment. METHODS:A computer-based search of CNKI, PubMed and FMJS was performed for articles concerning stem cel transplantation and IBD published after January 2002. The key words were stem cells, inflammatory bowel diseases, Crohn's diseases, ulcerative colitis, cell therapy in Chinese and English respectively. At last, 49 articles were included in result analysis. RESULTS AND CONCLUSION: Embryonic stem cells and adult stem cells both have certain therapeutic benefits in IBD. But which kind of stem cell is the safest and most efficacious cannot be confirmed, and at the same time the most effective and the optimal dose and way of transplantation of such cells are still unclear. All in all, there is still a lot of work to do to remove the obstacles.
8.Characteristics of ethylcellulose microcapsules containing tubeimoside and its usage in the experimental study of renal arterial chemoembolization
Haiyun ZHU ; Zhentang LIU ; Xinghua LI
Chinese Journal of Radiology 2001;35(2):107-109
Objective To study the efficacy, safety and related characteristics of ethylcellulose microcapsules containing tubeimoside as a vascular embolization agent. Methods The ethylcellulose microcapsules containing tubeimoside was prepared using tubeimoside from bolbostemma paniculatum of Chinese medicinal herb as the core, and ethylcellulose as the shell. Transcatheter renal arterial embolization was performed with the microcapsules in 30 New Zealand white rabbits. Results The microcapsules were white, spherical, and smooth particles, with its size to range from 40-180 μm, and its drug content was 36%(W/W); It was divergened best in 40% meglucamine diatrizoate and suspended stably, easily injected through 3 F catheter without occlusion. All of the microcapsules ruptured in about 20 days when immersed in physiological saline at 37℃. The embolized kidneys were smaller than the normal kidneys in weight and volume after 30 days(tw=102.1, tv=38.0, P<0.001). Serial slices of the kidneys showed that the microcapsules remained mainly at the interlobular artery and the arterial arch, which measured from 110 μm to 350 μm in diameter. The vessels maintained occlusive after 30 days without formation of collateral circulation. Conclusion Ethylcellulose microcapsules containing tubeimoside were safe and effective with angioembolic function and slow-release. It was a potential peripheral artery embolization agent.
9.A study of the serum levels of thyroid hormone in elderly patients with chronic severe congestive heart failure and the efficacy of thyroid hormone treatment
Haining LIU ; Xinghua ZHANG ; Qingxin GENG
Chinese Journal of Geriatrics 2003;0(11):-
Objective To study the relationship between the serum levels of thyroid hormone and the degree of the congestive heart failure as well as the effects of thyroxine on elderly patients with chronic severe congestive heart failure(CHF). Methods 140 cases were divided into group A (60 cases of CHF classes Ⅰ and Ⅱ) and group B (80 cases of CHF classes Ⅲ and Ⅳ) according to the NYHA classification of severity of heart failure. The group B was divided into the observation group (50 cases) and the control group (30 cases) . All patients were treated with conventional methods and thyroxine 20-40 ?g every morning was added in the observation group for 4 weeks. The serum FT 3 ,FT 4 ,TSH,HR,echocardiography and heart function were examined before and after treatment. Results ⑴ Both group A and B had lower base line serum FT 3 and FT 4 ,which were significantly lower in the group B than those in the group A 〔FT 3 : (4.22?0.61) pmol/L vs(3.07?1.10)pmol/L,P
10.The treatment of extremity fractures using the interlocking nail
Lin SUN ; Xinghua LIU ; Xuesong WANG
Chinese Journal of Orthopaedics 2001;0(03):-
Objective To evaluate the effect of the interlocking nail for extremity fractures. Methods This study reviews 1224 cases of extremity fractures treated with locking intramedullary nail fixation from October 1996 to June 2004, including 92 cases humeral shaft fracture; 210 cases intertrochanteric fractures; 488 cases femoral shaft fractures; 92 cases supracondylar femoral fractures; 342 cases tibia and fibular fractures. According to the AO classification there were 642 type A, 364 type B and 218 type C. There were 986 cases (72.4%) high-energy injury; 405 cases were multiple injury. There is 778 male and 446 female with mean age 39 years (range 16-92 years). Duration from injury to operation was 8 days(3 hour-30 days). Close reduction was 1203 cases and open reduction were 21 cases. Results Mean follow-up period is 24 months(6-70 month), mean operation time was 90 minutes(40-480 minutes). Union was in 1204 cases, union rate was 98.2%, mean union time was 5 months (3-12 months) on average, there were nonunion in 22 patients: 4 in humeral shaft, 8 in femoral shaft, 4 in supracondylar femur, 6 in tibia shaft, the nonunion rate is 1.8%. Late deep infection occurred in 3 patients: 1 in femoral shaft, 1 in supracondylar femur, 1 in intertrochanteric femur, the infection rate is 0.2%. There were 16 split in intraoperation: 4 in humeral nail, 4 in Gamma nail, 9 in supracondylar nail. Iatrogenic nerve palsy occurred in 6 patients: 2 in radial nerve, 2 in sciatic nerve, 2 in common peroneal nerve, the occurrence is 0.4%. One femoral nail was broken, locking screw were broken in 9 patients (0.6%), femoral shaft fracture of distal nail end occurred in 3 cases: 1 in Gamma nail, two in supracondylar nail. 53 patient complained uncomfortable in entry point (8 shoulders; 9 hips; 36 knees). Conclusion The result is satisfactory in bone healing low infection reduced blood loss and rapid recovery of the joint and body with the close interlocking nailing to be treatment of fresh extremity shaft fracture. It is a perfect method, however the complication should be pay more attention.