Objective To explore the effects of automobil exhaust on immune adherence function of erythrocytes in mice Methods The male Kunming mice were exposed to gasoline fueled engine exhausts 20 minutes per day continouusly for 20 days After the whole exposure,the ratio of spleen to body weight and total count of erythrocytes in peripheral blood of mice were observed The immune adherence function of erythrocytes was determined by complement sensitized yeast cell hemagglutination test in mice Results The ratio of spleen to body weight [(4.84?0.53)mg/g] and total count of erythrocytes [(5 83?10 12?0 25?10 12)/L] of mice exposed to automobil exhausts were significantly lower than those of control group [(5 55?0 68)mg/kg,(7 71?10 12?0 29?10 12)/L] respectively The positive rate of blood coagulation of exposure group (12 5%) was significantly lower than that of control group (82 5%) at blood coagulation titer of 1∶8,? 2=39 2,P

Objective To report the long-term follow-up results on treating bladder transitional cell carcinoma with orthotropic ileal neobladder after radical cystectomy.Methods Thirty-three male patients with a mean age of 64 years were subjected to Carney Ⅱ orthotropic ileal neobladder oper-ation after cystectomy.The entire length of ileum was opened along the antimesenteric border,placed into a transverse U shape,and sutured with a running suture.The bottom of the U shape was anasto-mosed with urethra to reconstruct the urinary continuity.The perioperation mortality,complications,urinary continence,renal function,image findings,and urodynamic examination were all retrospec-tively investigated.The quality of life was evaluated using the Functional Assessment of Cancer Ther-apy-Bladder(FATC) and International Prostate Symptom Score (IPSS).Results Thirty patients were followed up for 12-60 months.Urodynamics was carried out after oporation.The average ca-pacity of the urinary reservoir,the peak flow rate and postvoid residual were (380±65) ml,(12.6±2.3) ml/s and (25±11) ml,respectively.But the intra-reservoir pressure was significant lower than the intra-urethra pressure(20.4±8.7 cm H2O vs.57.2±10.5 cm H2O).Twenty-eight patients had a satisfactory daytime urinary continence and 26 patients had a satisfactory nocturnal urinary continence.The total FACT was 110.5±16.0 and IPSS was 14.5±4.2.Conclusion CamyⅡ ileal neobladder is a satisfactory method for treatment of invasive bladder cancer after radical cystectomy; it has few com-plication and is clinically valuable.

Dental Implantation ; standards ; Humans ; Terminology as Topic

OBJECTIVETo assess the efficacy of Yishen Jiejing Decoction (YJD) in treating poststroke shoulder-hand syndrome (SHS) patients of yin deficiency yang hyperactivity with blood stasis stagnation collaterals syndrome.

METHODSTotally 60 SHS patients of yin deficiency yang hyperactivity with blood stasis stagnation collaterals syndrome were randomly assigned to two groups, the treatment group and the control group, 30 cases in each group. Conventional rehabilitation training and therapeutics were applied in all patients. Besides, patients in the treatment group took 50 mL YJD, twice a day. One month without interruption consisted of one course of treatment. The curative effects of each group were evaluated respectively before treatment and at one month after treatment. The neurologic impairment, TCM syndrome, and the improvement of upper limbs movement were assessed by the neurologic impairment integral, scoring for TCM syndrome diagnostics, Fugl-Meyer Assessment (U-FMA). Adverse reactions were observed at the same time.

RESULTSThe effective rate of stroke was 86.67% and the effective rate of SHS was 90.00% in the treatment group, higher than those of the control group (P < 0.05). Both groups got improvement in neurologic impairment, stroke induced blood stasis syndrome, yin deficiency yang hyperactivity syndrome, and the improvement of upper limbs movement after treatment (all P < 0.05). Besides, all the improvement was obviously superior in the treatment group (P < 0. 05). No adverse reaction occurred during the course of treatment.

CONCLUSIONThe curative effect of YJD combined with conventional rehabilitation training was confirmative and superior to the control group.

Aged ; Drugs, Chinese Herbal ; therapeutic use ; Female ; Humans ; Male ; Middle Aged ; Reflex Sympathetic Dystrophy ; drug therapy ; etiology ; rehabilitation ; Stroke ; complications ; Treatment Outcome ; Yin Deficiency ; drug therapy ; Yin-Yang

Objective To evaluate which parameters of transvaginal color Doppler ultrasonography(TVCDU) can effectively reflect blood flow in ovarian tumors. Methods TVCDU was preoperatively used to determine all the parameters of blood flow in 60 women with epithelial ovarian cancer(EOC) and 36 with benign ovarian cystadenomas (control group). Microvessel density(MVD) was tested in the tissue samples by immunohistochemical method(SP method). The parameters of TVCDU in EOC were compared with those in control group.The correlation between MVD and the parameters in EOC group and control group was analyzed. Results ①Statistical differences of arteria showing rate, arteria number, vasculature type, diastolic notch, PI, RI, S/D, TAMXV were seen between EOC group and control group(P

Objective To investigate the oxidative stress caused by tri-n-butyltin (TBT) in mice. Methods 24 male NIH mice were chosen and the different doses of TBT were given per os for 24 h acute toxic test, meanwhile set the control group of 0.9% sodium chloride and 13% ethanol. The TOSC of heart, brain, lung, liver and kidney homogenates were detected by gas chromatography. Results After 24 h TBT exposure, TOSC of all viscera tissues was increased and this change was significant in the heart and brain, in every dose level, compared with the control (P

[Objective]To demonstrate mechanism of ESW in curing osteogetic disorders,we studied expression of some osteogenetic factors in human mesenchymal stem cells(hMSCs)when exposed to ESW.[Method]After success in marrow aspiration,isolation and obtainment optimal experimental energy,a dose of 5kV and 100 times of ESW was applied to hMSCs of passage 1.The expression of IGF-Ⅰ and TGF-?1 were examined by immunocytochemical staining.[Result]The cytochemical staining results showed that expression of IGF-Ⅰ and TGF-?1 appeared at different passage of hMSCs after ESW intervention.Appearance of IGF-Ⅰ was earlier than TGF-?1 which didnt express until passage 7.At the same interval,the expression of IGF-Ⅰ and TGF-?1 in control group difference is lower than ESW group,respectively(P

Objective To explore the characteristics of fetal movement and FHR variation elicited by acoustic stimulation and whether acoustic stimulation can replace vibroacoustic stimulation. Methods Ninety-four and seventy-six normal pregnant women for antenatal visit were recruited from the Woman's Hospital, School of Medicine, Zhejiang University from April 2002 to February 2003. All subjects were divided into 5 groups to be exposed to five different intensities of acoustic stimulations at 95,100,105,110,115 dB respectively and self-control of blank and vibroacoustic stimulation were designed. The fetal movements and FHR were recorded during the study. Results (1) The percentage of fetal movement evoked by 95,100,105,110,115 dB airborne sound was 15% , 89%, 83% , 83% , 95% respectively. The total percentage of fetal movement evoked by vibroacoustic stimulation was 99% for all subjects. The percentages of evoked fetal movement by 100,105,110,115 dB airborne sound were not significantly different from those by vibroacoustic stimulation. (2)The percentages of FHR acceleration ≥15 bpm in 100,105,110 and 115 dB airborne sound groups were 39%, 61%, 56% and 85%, respectively, while 92% for all cases evoked by vibroacoustic stimulation was significantly higher than those evoked by 100,105 and 110 dB airborne sound group but with no significant difference to 115 dB airborne sound group. (3)The peak value in FHR evoked by 95,100,105, 110 and 115 dB airborne sound were -4. 5 bpm, 12 bpm, 17 bpm, 14 bpm and 20. 5 bpm, respectively. The peak FHR acceleration evoked by vibroacoustic stimulation was 23 bpm which was significantly higher than those by 100,105,110 dB airborne sound and no significant difference was detected between 115 dB airborne sound and vibroacoustic stimulation group. (4)Compared with 115 dB airborne sound, vibroacoustic stimulation evoked significantly longer duration of FHR tachycardia (42. 5 s vs 5 s, P = 0. 011) and fetal movement (270 s vs 100 s, P = 0. 000). Conclusions Acoustic stimulation at 115 dB is able to elicit efficient fetal movement and FHR acceleration without prolonged tachycardia, fetal behavioral disorganization or excessive fetal movement and is reasonable to replace vibroacoustic stimulation for awaking fetuses combined with NST.

RNAi is a process of effective gene silencing. Human papillomaviruses 16 (HPV16), as the most prevalent genotype of cervical cancer, encodes the E6 and E7 oncogenes, which is pivotal for maintenance of malignant phenotypes. Recently, some significant advances have been obtained in RNA interfering effect on HPV16 E6/E7. In vitro, it has been developed more effective vector systems and screened for more specific targeted sequences. In vivo, the corresponding animal models have been established, which lay a good foundation for the clinical research.

Objective To investigate the value of dialysis and ethics of withdrawal dialysis.Method Through analysis of some typical cases of ESRD patients,to investigate the value of dialysis.Conclusion A lot of ESRD patients can survive through dialysis,thanks to the improvement of medical science in last 30 years.On the other hand,it can also keep some patients with no living calculation surviving,becoming the burdensome of families,hospitals and societies.Our object is to discuss the ethics of withdrawal dialysis in our country.