1.Extracorporeal shock wave therapy for nonunion or delayed osseous union: Animal experiment and clinical follow-up
Chinese Journal of Tissue Engineering Research 2010;14(9):1625-1628
BACKGROUND:Extracorporeal shock wave (ESW) therapy is using principles of liquid-electric conversion and transfer to produce energy gradient difference and torsional tension in tissues with varied density.It is a matured technique in treating urinary and digestive system calculosis.However,the applications of ESW in treating nonunion or delayed osseous union are few.OBJECTIVE:To explore the therapeutic effects of ESW in treating nonunion or delayed osseous union by animal experiment and clinical verification.METHODS:The effect of ESW on periosteal metabolism was explored by focusing extracorporeal wave on bone tissues,and the autoradiography of H~(3-)TdR labeling rate was observed by animal experiment.ESW was used to treat nonunion patients (n=16) or delayed osseous union patients (n=16),and the follow-uP results were evaluated.RESULTS AND CONCLUSION:By autoradiography,the H~(3-)TdR labeling rate was greater in the experimental sides than that of the control sides at 1 and 2 weeks after operation (P<0.05-0.01),which confirmed that the mitotic activity of periosteal osteoblasts was increased,namely,endosteal osteogenesis was enhanced.Clinical verification results demonstrated that,at 16 weeks after operation,16 patients with delayed union were all cured,13 were cured among the 16 cases of nonunion,and the remained 3 cases had notably callus formation.No adverse events occurred in all cases.The results suggested that it is reliable to treat nonunion or delayed osseous union using ESW therapy.
2.Clinical Study on Xiaoxuan Kangfu Capsule in the Treatment of Psoriasis Vulgaris
International Journal of Traditional Chinese Medicine 2008;30(5):361-362
Objective To investigate the therapeutic effect of Xiaoxuan Kangfu capsule in treating psoriasis vulgaris. Methods All patients were divided into two groups randomly (60 patients in a control group and 60 patients in a treatment group). In the control group complex Qingdai capsule was given to the patients, with 4 pills for each time and 3 times daily. While in treatment group Xiaoxuan Kangfu capsule was given to the patients with 6 pills for each time and twice daily. 30 days consisted one treatment period for both groups. The patients undertook one to three treatment period according to the patients' pathogenetic condition. The rates of recovery and improvement and were compared. Results In the treatment group, 34 patients were cured (42.5%), and the total effective rate was 87.5%; while in the control group 14 patients were cured (7.5%), and the total effective rate was 72.5%. There was statistic difference between the two groups (P<0.05). The average heal time of the treatment group was shorter than that of the control group, showing statistic difference (P<0.05).Conclusion Xiaoxuan Kangfu capsule showed higher recovery rate, shorter healing time and lower recurrence rate in treating psoriasis vulgaris than complex Qingdai capsule. The treatment is deserving clinical spread.
3.Analysis and identification of IR on different parts ofCynanchumchinese R.Br
International Journal of Traditional Chinese Medicine 2015;(3):255-257
ObjectiveTo identify the chemical composition of stem, leaf and peel ofCynanchumchinese R.Br..MethodsFourier IR spectra, the second derivative spectrum and two-dimensional correlation spectroscopy were adopted to identify IR of different parts ofCynanchumchinese R.Br..ResultsIt was found that the IR spectra of the leaf was similar to that of the peel but was different from the stem. What’s more, in the second derivative spectra of the leaf, it showed that the absorption peak was strong at the position of 1 543 cm-1, 1 515 cm-1, 1 499 cm-1 and 1 467 cm-1, respectively and there existed carbonyl absorption peak at 1 738 cm-1 and 1 659 cm-1 in addition. Therefore, it was inferred that flavonoids were the major components while less in the stem and peel.ConclusionsThe differences of the three parts aboutCynanchumchinese R.Br. were studied through IR spectrum macroscopically, which provided reference for exploring the constituents and clinical medication.
5.The development tendency of modern implantology.
Chinese Journal of Stomatology 2003;38(4):241-243
8.The Effects of Intensive Insulin Therapy on the ? Cell of Islets of Pancreas in Incipient Type Diabetes Patients
Journal of Medical Research 2006;0(08):-
0.05);The levels of basal FINS showed a significant differences between group A and group B(P0.05).Conclusions Intensive insulin treatment to newly diagnosed type 2 diabetes patients can control blood glucose rapidly to a desired level,and can recover the function of B cell better than traditional oral hypoglycemic agents by dissolving the virulence of glucose rapidly.
9.Influence of ~(131)Ⅰ on gonadal gland in the treatment of hyperthyroidism
Chinese Journal of Endocrinology and Metabolism 2000;0(06):-
Gonadal gland is one of the highly sensitive organs to ionizing radiation,but there is a threshold dose for gonadal sterility caused by ionizing radiation.When ~(131)Ⅰis applied in the treatment of patients with hyperthyroidism,the usually absorbed radiation dose of gonadal gland is below the threshold.It is documented that ~(131)Ⅰtherapy for fertile women or adolescents and children with hyperthyroidism does not cause reduction in fertility and does not increase the incidence of genetic defects.Therefore ~(131)Ⅰtherapy,for adolescents and children with hyperthyroidsm,who have been failed in anti-thyroid drug therapy,refused surgical treatment or were contraindicated in surgery,is another better available therapeutical modality.
10.The effect of gonadectomy on mortality and left ventricular function of experimental myocardial infarction in male and female rats
Chinese Journal of Pathophysiology 1986;0(03):-
The effects of gonadectomy on mortality and left ventricular function following myocardial infarction (MI) were observed. Ligation of the left coronary artery or sham-operation was performed three weeks after gonadcctomy in male and female rats. The results showed that the mortality rate within 9 days after MI was lower in male gonadectomy group (GMI) than in control group (CMI), but there was no significant difference between female GMI and CMI. For the sham-operated rats, dp/dtmax, -dp/dtmax and LVSP, measured on the 9th day after operation, were much lower in male gonadectomy group (CS) than in male control group (CS), but these indeces showed no significant differences between male GMI and CMI, and also between male GMI and GS. The increase of the diameter of septal myocardial fiber in male GMI was more marked than in male CMI, but in female GMI it was less marked than in female CMI. It is suggested that the activity of gonads is involved in the compensation and recovery of LV function after MI.