1.Clinical Study on Xiaoxuan Kangfu Capsule in the Treatment of Psoriasis Vulgaris
International Journal of Traditional Chinese Medicine 2008;30(5):361-362
Objective To investigate the therapeutic effect of Xiaoxuan Kangfu capsule in treating psoriasis vulgaris. Methods All patients were divided into two groups randomly (60 patients in a control group and 60 patients in a treatment group). In the control group complex Qingdai capsule was given to the patients, with 4 pills for each time and 3 times daily. While in treatment group Xiaoxuan Kangfu capsule was given to the patients with 6 pills for each time and twice daily. 30 days consisted one treatment period for both groups. The patients undertook one to three treatment period according to the patients' pathogenetic condition. The rates of recovery and improvement and were compared. Results In the treatment group, 34 patients were cured (42.5%), and the total effective rate was 87.5%; while in the control group 14 patients were cured (7.5%), and the total effective rate was 72.5%. There was statistic difference between the two groups (P<0.05). The average heal time of the treatment group was shorter than that of the control group, showing statistic difference (P<0.05).Conclusion Xiaoxuan Kangfu capsule showed higher recovery rate, shorter healing time and lower recurrence rate in treating psoriasis vulgaris than complex Qingdai capsule. The treatment is deserving clinical spread.
2.Extracorporeal shock wave therapy for nonunion or delayed osseous union: Animal experiment and clinical follow-up
Chinese Journal of Tissue Engineering Research 2010;14(9):1625-1628
BACKGROUND:Extracorporeal shock wave (ESW) therapy is using principles of liquid-electric conversion and transfer to produce energy gradient difference and torsional tension in tissues with varied density.It is a matured technique in treating urinary and digestive system calculosis.However,the applications of ESW in treating nonunion or delayed osseous union are few.OBJECTIVE:To explore the therapeutic effects of ESW in treating nonunion or delayed osseous union by animal experiment and clinical verification.METHODS:The effect of ESW on periosteal metabolism was explored by focusing extracorporeal wave on bone tissues,and the autoradiography of H~(3-)TdR labeling rate was observed by animal experiment.ESW was used to treat nonunion patients (n=16) or delayed osseous union patients (n=16),and the follow-uP results were evaluated.RESULTS AND CONCLUSION:By autoradiography,the H~(3-)TdR labeling rate was greater in the experimental sides than that of the control sides at 1 and 2 weeks after operation (P<0.05-0.01),which confirmed that the mitotic activity of periosteal osteoblasts was increased,namely,endosteal osteogenesis was enhanced.Clinical verification results demonstrated that,at 16 weeks after operation,16 patients with delayed union were all cured,13 were cured among the 16 cases of nonunion,and the remained 3 cases had notably callus formation.No adverse events occurred in all cases.The results suggested that it is reliable to treat nonunion or delayed osseous union using ESW therapy.
3.Analysis and identification of IR on different parts ofCynanchumchinese R.Br
International Journal of Traditional Chinese Medicine 2015;(3):255-257
ObjectiveTo identify the chemical composition of stem, leaf and peel ofCynanchumchinese R.Br..MethodsFourier IR spectra, the second derivative spectrum and two-dimensional correlation spectroscopy were adopted to identify IR of different parts ofCynanchumchinese R.Br..ResultsIt was found that the IR spectra of the leaf was similar to that of the peel but was different from the stem. What’s more, in the second derivative spectra of the leaf, it showed that the absorption peak was strong at the position of 1 543 cm-1, 1 515 cm-1, 1 499 cm-1 and 1 467 cm-1, respectively and there existed carbonyl absorption peak at 1 738 cm-1 and 1 659 cm-1 in addition. Therefore, it was inferred that flavonoids were the major components while less in the stem and peel.ConclusionsThe differences of the three parts aboutCynanchumchinese R.Br. were studied through IR spectrum macroscopically, which provided reference for exploring the constituents and clinical medication.
4.On Wu Songkang’s Scholar Thought and Clinical Experiences on TCM Internal Medicine
Xing WU ;
Journal of Zhejiang Chinese Medical University 2006;0(04):-
Doctor Wu Songkang’s scholar thought and clinical experiences on TCM internal medicine are mainly featured with emphasis on analyzing and differentiating pathological conditions in accordance with the eight principal syndromes,from defining disease nature,recognizing diseased organs and position;not dealing with the same “syndrome” on chronic and refractory diseases,continually differentiating with the changing symptoms,the method being changed with different symptoms,drug with syndromes.
5.Biocompatible disadvantages and modern modifications of medical silicone rubber
International Journal of Biomedical Engineering 2008;31(6):358-361
Silicone rubber with advantages of stable performance, easy-shaping, considerable product bene- fits, has been widely used in biomedical engineering field and health care industries. Nevertheless, the application of silicone rubber in biomedicine is still challenged by its inherent shortcomings. In biocompatibility aspects, disad- vantages of silicone rubber products need to be overcome, including.'hydrophobic surface, poor imaging compatibili- ty, and occurrence of calcification after long-term implantation in body. Experts from all over the world have been studying on means of modifications over the past few years and the researches mainly focus on increasing the surface wettability, enhancing the function of X-ray resistance, and anti-calcification pre-treating. Although initial results are encouraging, biocompatibility of medical silicone rubber is not yet satisfactory.
6.Leukemic stem cells target therapy
Journal of International Oncology 2009;36(1):63-65
It is proposed that surviving leukemia stem cell (LSC) is a major contributing factor to leu-kemic relapse because of its molecular and cellular features.Several recent studies have proved that LSC can be eliminated by target therapy.
7.Progresses of diagnosis and therapy in multiple acyl-CoA dehydrogenase deficiency
International Journal of Pediatrics 2010;37(5):518-521
Multiple acyl-CoA dehydrogenase deficiency (MADD) is a common inborn error of fatty-acid metabolism characterized by vomiting, acidosis and lipid storage myopathy, and the clinical manifestations of MADD are highly heterogeneous. MADD can be diagnosed by the elevation of multiple acyl-carnitine in blood and glutaric acid or other organic acid in urine. The neonatal-onset patients have severe symptoms and poor prognosis. However, oral riboflavin supplementation (can completely rescue) ameliorate the clinical and laboratory disorders rapidly especially to the riboflavin responsive MADD. Additionally, patients not sensitive to riboflavin should also take low lipid, low protein and high carbonhydrate diet besides riboflavin.
8.Clinical application of covered stents in treating esophageal malignant stenosis
Chinese Journal of Tissue Engineering Research 2010;14(4):702-705
OBJECTIVE: To explore the materials and selection of esophageal stents, and to discuss the application of covered stants in treating esophageal malignant stenosis.METHODS: CNKI and Medline databases were retrieved by computer for papers published from 1980 to 2009 with search terms of "esophageal carcinoma, esophageal stenosis, esophageal stent, and fabric-covered metallic stent". The language was limited for Chinese and English. A total of 61 iteratures were initial searched by computer, according to inclusive and exclusive criteria, 29 literatures were selected by the first author. Problems including esophageal stent category, material selection, as well as application of covered stents in treating esophageal malignant stenosis were reviewed and summarized.RESULTS: Totally 29 literatures were included in this paper. No concealed allocation or blinding method was described in the literatures. According to preparing materials, the stents could be divided into stainless metal stent, memory metallic stent and polyester plastic stent. As tissue-engineered materials, stents could be assigned into biodegradable polymer matrix stent and non-degradable biodegradable polymers stent. Each material stent possesses distinct advantage and disadvantage. The covered stents could relief esophageal stenosis effectively, interrupt tumor growth, and prevent restenosis. CONCLUSION: As a palliative therapy for treating esophageal malignant stenosis, covered stents can elevate patients' life quality and prolong survival times.
9.Implementation Strategies of Hospital Information System
Journal of Medical Informatics 2009;30(8):17-20
By introducing the job contents classification of hospital, the paper analyzes each sub-system including its information contents, structure features and construction factors, discusses the plan for establishing electronic medical records with combination of the component of medical records, from sequencing of the system, management mode, noted issues, moreover, suggests that each hospital should accord to own situation establishing own system.
10.The early enteral feeding and rehabilitation of severely burned patients
Chinese Journal of Tissue Engineering Research 2002;6(22):3461-
Objective To explore the effect of rehabilitation through analysis the early enteral feeding on the prevention of enteral infection in severely burned patients .Method A total of 22 patients with severe burns were randomly divided into an early enteral feeding group (EF) and a delayed enteral feeding group (DF). The levels of serum endotoxin were detected in the members of both groups in 1, 3, and 5 days .Result The levels of serum endotoxin in severely burned patients were significantly higher than in normal subjects (P< 0.01) . The levels of serum endotoxin in the EF group were significantly lower than in the DF group (P< 0.01). Conclusion Early enteral feeding may decrease enterogenic infection and it helps the nutrition support, improve the patient resistance, facilitate the repair of damaged tissue , so it contributes to the rehabilitation of burned patients.