BACKGROUND:Extracorporeal shock wave (ESW) therapy is using principles of liquid-electric conversion and transfer to produce energy gradient difference and torsional tension in tissues with varied density.It is a matured technique in treating urinary and digestive system calculosis.However,the applications of ESW in treating nonunion or delayed osseous union are few.OBJECTIVE:To explore the therapeutic effects of ESW in treating nonunion or delayed osseous union by animal experiment and clinical verification.METHODS:The effect of ESW on periosteal metabolism was explored by focusing extracorporeal wave on bone tissues,and the autoradiography of H~(3-)TdR labeling rate was observed by animal experiment.ESW was used to treat nonunion patients (n=16) or delayed osseous union patients (n=16),and the follow-uP results were evaluated.RESULTS AND CONCLUSION:By autoradiography,the H~(3-)TdR labeling rate was greater in the experimental sides than that of the control sides at 1 and 2 weeks after operation (P＜0.05-0.01),which confirmed that the mitotic activity of periosteal osteoblasts was increased,namely,endosteal osteogenesis was enhanced.Clinical verification results demonstrated that,at 16 weeks after operation,16 patients with delayed union were all cured,13 were cured among the 16 cases of nonunion,and the remained 3 cases had notably callus formation.No adverse events occurred in all cases.The results suggested that it is reliable to treat nonunion or delayed osseous union using ESW therapy.

Objective To investigate the therapeutic effect of Xiaoxuan Kangfu capsule in treating psoriasis vulgaris. Methods All patients were divided into two groups randomly (60 patients in a control group and 60 patients in a treatment group). In the control group complex Qingdai capsule was given to the patients, with 4 pills for each time and 3 times daily. While in treatment group Xiaoxuan Kangfu capsule was given to the patients with 6 pills for each time and twice daily. 30 days consisted one treatment period for both groups. The patients undertook one to three treatment period according to the patients' pathogenetic condition. The rates of recovery and improvement and were compared. Results In the treatment group, 34 patients were cured (42.5%), and the total effective rate was 87.5%; while in the control group 14 patients were cured (7.5%), and the total effective rate was 72.5%. There was statistic difference between the two groups (P＜0.05). The average heal time of the treatment group was shorter than that of the control group, showing statistic difference (P＜0.05).Conclusion Xiaoxuan Kangfu capsule showed higher recovery rate, shorter healing time and lower recurrence rate in treating psoriasis vulgaris than complex Qingdai capsule. The treatment is deserving clinical spread.

ObjectiveTo identify the chemical composition of stem, leaf and peel ofCynanchumchinese R.Br..MethodsFourier IR spectra, the second derivative spectrum and two-dimensional correlation spectroscopy were adopted to identify IR of different parts ofCynanchumchinese R.Br..ResultsIt was found that the IR spectra of the leaf was similar to that of the peel but was different from the stem. What’s more, in the second derivative spectra of the leaf, it showed that the absorption peak was strong at the position of 1 543 cm-1, 1 515 cm-1, 1 499 cm-1 and 1 467 cm-1, respectively and there existed carbonyl absorption peak at 1 738 cm-1 and 1 659 cm-1 in addition. Therefore, it was inferred that flavonoids were the major components while less in the stem and peel.ConclusionsThe differences of the three parts aboutCynanchumchinese R.Br. were studied through IR spectrum macroscopically, which provided reference for exploring the constituents and clinical medication.

Abstract: Parasites such as schistosome, liver fluke, and echinococcus mainly parasitize or cause diseases in the liver, and liver fibrosis is the main pathological feature and primary cause of morbidity and mortality of hosts after infection. The liver fibrosis caused by these parasites still has a heavy disease burden in the world, and due to its unique disease characteristics, the animal model of liver fibrosis caused by parasites has a unique position in the study of liver fibrosis. The essential distinguishing feature of parasitic infection-induced hepatic fibrosis from other types of hepatic fibrosis is the variety of parasitic-secreted molecules initiating fibrosis, including proteins, nucleic acids, lipids, metabolic small molecules and other types. These molecules induce the formation of type 2 immunity or inflammatory microenvironment in the host liver. Although in-depth research has been conducted on the initiation, maintenance, and regression of type 2 immunity in the liver after parasitic infection, many core mechanisms remain unclear. Chronic inflammation ultimately activates stellate cells and other types of cells to differentiate into myofibroblasts (MF), thus promoting the formation of liver fibrosis. After clearing parasites, MF may undergo reverse differentiation, apoptosis or senescence, and liver fibers may undergo reversal. Deep research on the activation and regression of MF is the foundation for effective prevention and treatment of liver fibrosis. This article reviews the disease burden and pathological characteristics of liver fibrosis caused by parasite infection.

Objective To study the microscopic anatomy of the facial nerve trunk,and provide some important morphometric data about facial-hypoglossal nerve anastomosis.Methods The cervical course and adjacent structures of the hypoglossal nerve were observed on 5 adult cadavers;the facial nerve trunk (from stem hole to fork of breast of facial nerve) and the distance from mastoidale to stem hole and sectional area of hypoglossal nerve frunk were measured.The operation was imitate on 5 cadavers.Results The length of the facial nerve trunk was ( 15.71 ± 1.97) mm,its diameter upon its emergence from the foramen was( 2.57 ± 0.60) mm.The distance between the bifurcation and the mastoidale was ( 18.20 ± 4.40)mm.The distance between the bifurcation and the mandibular angle was (39.91 ± 8.38) mm.The distance between the mastoidale and the stylomastoid foramen was (17.91 ±2.68) mm.The facial nerve trunk was monofascicular with across-sectional area of 4.6-5.7 (5.1 ± 0.2) mm2.The number of the fasciculus and the cross-sectional areas of the nerve trunk and the fasciculus were 1-4 ( 1.6 ± 0.8) bind,6.8-8.0 (7.5 ± 0.7)mm2,and 4.1-5.5 (4.7 ±0.6) mm2,rospectively,at the distance their number were 1-5 (3.6 ±0.5) bind,4.9-6.1 (5.6 ± 0.5) mm2.Conclusion Hypoglossal nerve and facial nerve anastomosis and facial-hypoglossal nerve anastomosis into the graft could be used in patients,and hypoglossal nerve function can be achieved to minimize the effect of the collapse.

The incidence of colorectal cancer increased yearly,and more than 50％ patients had liver metastases.As continuous development of recognition and treatment of colorectal liver metastases,it now has been reckoned as a potentially curable disease,and its prognosis has been improved significantly.However,how to choose the reasonable treatment is a problem for us.The standardized treatment of colorectal liver metastases should include imaging examination,surgical treatment and multi-disciplinary treatment,and individualized treatment should be considered.In this article,the selection of proper imaging examination,comparison of different treatment methods,surgical treatment of liver metastases and multi-disciplinary treatment are discussed.

Objective:To study the correlation between medical professionalism construction and hospital serv-ice quality improvement .Methods:Questionnaire was used to collect data about patients feedbacks of medical pro -fessionalism in the third-level hospitals in Baoji in 2013 .The correlation between doctors'performance and public services and improving the hospital service quality was analyzed .Results:Occupation responsibility , doctor-pa-tient integrity , doctors giving patients help , medical fees , service consciousness , attitude , quality and efficiency have related to improving the hospital service quality .Conclusion:The Hospital should strengthen the communica-tion between doctors and patients , pay attention to the humanistic quality training , improve the quality of hospital service .

OBJECTIVE: To explore the materials and selection of esophageal stents, and to discuss the application of covered stants in treating esophageal malignant stenosis.METHODS: CNKI and Medline databases were retrieved by computer for papers published from 1980 to 2009 with search terms of "esophageal carcinoma, esophageal stenosis, esophageal stent, and fabric-covered metallic stent". The language was limited for Chinese and English. A total of 61 iteratures were initial searched by computer, according to inclusive and exclusive criteria, 29 literatures were selected by the first author. Problems including esophageal stent category, material selection, as well as application of covered stents in treating esophageal malignant stenosis were reviewed and summarized.RESULTS: Totally 29 literatures were included in this paper. No concealed allocation or blinding method was described in the literatures. According to preparing materials, the stents could be divided into stainless metal stent, memory metallic stent and polyester plastic stent. As tissue-engineered materials, stents could be assigned into biodegradable polymer matrix stent and non-degradable biodegradable polymers stent. Each material stent possesses distinct advantage and disadvantage. The covered stents could relief esophageal stenosis effectively, interrupt tumor growth, and prevent restenosis. CONCLUSION: As a palliative therapy for treating esophageal malignant stenosis, covered stents can elevate patients' life quality and prolong survival times.

By introducing the job contents classification of hospital, the paper analyzes each sub-system including its information contents, structure features and construction factors, discusses the plan for establishing electronic medical records with combination of the component of medical records, from sequencing of the system, management mode, noted issues, moreover, suggests that each hospital should accord to own situation establishing own system.

Multiple acyl-CoA dehydrogenase deficiency (MADD) is a common inborn error of fatty-acid metabolism characterized by vomiting, acidosis and lipid storage myopathy, and the clinical manifestations of MADD are highly heterogeneous. MADD can be diagnosed by the elevation of multiple acyl-carnitine in blood and glutaric acid or other organic acid in urine. The neonatal-onset patients have severe symptoms and poor prognosis. However, oral riboflavin supplementation (can completely rescue) ameliorate the clinical and laboratory disorders rapidly especially to the riboflavin responsive MADD. Additionally, patients not sensitive to riboflavin should also take low lipid, low protein and high carbonhydrate diet besides riboflavin.