Normal flora of intestine can transit under several clinical conditions,which may result in bacterial translocation and lead to various dysfunctions.Mild hypothermia,as an effective therapeutic method,not only has protective effects on vital organs such as heart and brain,but also impacts bacterial translocation,including intestinal mucosal blood flow,intestinal permeability,production of reactive oxygen species and cytokines.This paper reviewed the researches on the effect of mild hypothermia on intestinal bacterial translocation in recent years.

Objective To observe the anatomy of the inferior right hepatic veins (IRHV).Methods The IRHVs were divided into 3 groups according to the location where they entered into the retrohepatic inferior vena cava at: the upper 1/3, middle or lower 1/3. The incidence, number, caliber, extrahepatic length and the relationship between the major hepatic veins (the right, middle and the left hepatic veins) and the IRHV were observed and measured in 60 adult cadavers. Results The incidence of IRHV was 83.33% with an average diameter of 2.62-18.46(14.32±1.21)mm. Its extrahepatic length was 3.26-47.65 (10.78±7.81)mm. There was a marked negative correlation between the diameter of the IRHV and its number, a marked negative correlation between the diameter of the IRHV and the diameter of the right hepatic vein and a marked positive correlation between the number of the IRHV and the diameter of the right hepatic vein. Conclusions There were high variations in the incidence and anatomy of the IRHV which were related to the diameter of the right hepatic vein. The IRHV was not to be torn during liver resection and should be reconstructed in right liver grafts.

Objective To investigate the correlation between arrhythmia and left ventricular hypertrophy in patients withprimary hypertension. Methods 12-lead synchronous resting electrocardiogram. ambulatory electrocardiogram and echo-cardiogram were obtained from 246 patients with primary hypertension. Left ventricular mass index (LVMI ) was meas-ured as previous reference. Results The average LVMI of myocardium hypertrophy group (151.6? 15. 8g/m~2) signif-canily increased compared with that of the control group (P

Objective To investigate the relationship between ?-catenin gene expression and the mechanism of tumorigenesis, development and metastasis of human nasopharyngeal carcinoma. Methods RT-PCR method was used to detect the mRNA expression of ?-catenin in normal human nasopharyngeal tissues and nasopharyngeal carcinoma. Results The results showed that ?-catenin expression in 11 out of 15 nasopharyngeal carcinoma specimens was decreased (73.3%). Conclusion The abnormal expression of ?-catenin changed in the normal adhesive function and the signal transduction pathway of the cell in human nasopharyngeal carcinoma, indicating that the expression level of ?-catenin was a biological marker of tumorigenesis and development of human nasopharyngeal carcinoma.

Objective:To investigate the effects of TGF-? 1 and TGF-? 2 on cleft palate formation .Methods:30 pregnant NIH mice in experimental group were injected with dexamethasone (50 mg/kg) intr aperitoneally in GD 12 12 ,30 mice in control group were given the same vo lume of NS.Fetuses were removed out in GD13 12 ,GD14 12 and GD15 12 , heads of the mice were sliced in coronal plane.Expression of TGF-? 1 an d TGF-? 2 in embryonic palate were detected by immunohistochemical methods: Results:Dexamethasone (50 mg/kg) induced cleft palate in NI H embryos,and expression of TGF-? 1 and TGF-? 2 in palate tissues was h igher in the experimental group than that in the control (P

Objective To evaluate the clinical effect ofXugu-Huoxue decoction combined with anatomical reduction and internal fixation with cannulated screws in patients with femoral neck fractures. Methods A total of 89 patients with femoral neck fractures were randomly divided into a control group and a Xugu-Huoxuegroup according to the random number table, with 46 in the control group and 45 in the Xugu-Huoxuegroup. The control group was treated with anatomical reduction and internal fixation with cannulated screws, while theXugu-Huoxuedecoction group was treated withXugu-Huoxuedecoction on the basis of the control group. The hemodynamics of the femoral vein was evaluated with color Doppler sonography. Hip function was rated with Harris hip score.ResultsAfter 12 months of treatment, the minimum diastolic velocity (12.0 ± 2.2 cm/svs.9.3 ± 2.0 cm/s;t=3.675,P<0.01), diameter (0.8 ± 0.3 cm vs. 0.6 ± 0.1 cm;t=3.675, P<0.01) and blood flow (1 123.4 ± 271.1 ml/minvs.901.2 ±121.1 ml/min;t=5.067,P<0.01) of the femoral vein in theXugu-Huoxuedecoction group were significantly increased than those in the control group. The rates of excellent or good in theXugu-Huoxuedecoction group and the control group was 86.7% (39/45) and 63.0% (29/46), respectively, with statistically significant difference (χ2=5.529,P=0.019). There were 2 patients (4.4%) with delayed fracture healing and 2 patients (4.4%) with femoral head necrosis in theXugu-Huoxuedecoction group, while 3 patients (6.5%) with delayed fracture healing, 5 patients (10.9%) with femoral head necrosis inthe control group, without statically significant difference (χ2value were 0.000, 0.572,P value were 1.000, 0.449, respectively).ConclusionXugu-Huoxue decoction combined with anatomical reduction and internal fixation with cannulated screwscan improve the fracture prognosis and the joint function in patients with femoral neck fractures.

Objective We tried to investigate the current status of pediatric nursing post setting and analyze the practical application effect in the clinical working practice for the foundation of readjusting and setting up the pediatric nursing positions.Methods By convenient sampling method,the general condition and current post setting situation in the pediatric wards of 7 hospitals with self-designed questionnaires were investigated.The results underwent analysis Results The nursing post setting in pediatric wards of 7 hospitals were not all the same,nursing posts in the pediatric ward included three categories:management positions,teaching positions and clinical positions.Management positions included the head nurse,deputy head nurse and head nurse assistant; teaching positions included the teaching secretary and clinical total teaching nurse; the seven kinds of clinical nursing positions were office job,day shift,night shift,evening shift,midnight shift,late-morning shift,auxiliary job.Though some nursing jobs differed in the position names and working hours,their job contents were nearly identical.Conclusions Pediatric nursing post setting management in our country is still in the exploratory stage at present,it has not form a unified perfect job management system.Pediatric nursing positions should be set from the perspective of evidencebased theory,satisfying the demands of patients as the guidance,coming from clinical needs as the first principle,in the full implementation of the accountability for nursing and based on comprehensive consideration of various factors,so that the post setting can be scientific and reasonable.

Objective To observe the influence of polysaccharide from spirulina platensis(PSP) on human embryo lung diploid fibroblastic DNA damage and repair after UV irradiation. Methods After UV irradiation for 30min, the single cell gel electrophoresis(SCGE) was used to investigate the level of DNA damage, the level of DNA damage and repair at 30, 60, 90min were also investigated by SCGE respectively. Results The level of DNA damage induced by UV irradiation was prevented by PSP, and it also promote DNA repair capacity. Conclusion PSP can increase the activity of DNA endonuclease and DNA ligase in dose-de- pendrntly.

Adult ; Female ; Humans ; Motor Neuron Disease ; complications ; Neck ; pathology ; Thyroid Neoplasms ; complications

Objective To investigate the correlation between serum osteocalcin and type 2 diabetes mellitus (T2DM) in elderly patients.Methods A total of 55 T2DM patients (diabetic group) and 50 non-diabetic subjects (control group) aged ≥60 years were enrolled in this study.The levels of fasting blood glucose (FBG),glycated hemoglobin (HbAlc),insulin resistance index (HOMA IR),osteocalcin (OC),body mass index (BMI) and bone mineral density (BMD) in groups were compared.The correlations between serum osteocalcin and the above indicators were analyzed.Results The levels of OC and BMD were higher in control group than in diabetic group [(11.2±3.2)μg/Lvs.(4.1±3.0)μg/L,(-1.3±0.3) vs.(-2.6±0.5),respectively,both P＜0.05].The levels of FBG,HbAlc,FINS,HOMA-IR were lower in control group than in diabetic group [(4.7±2.0) mmol/L vs.(9.4±2.1) mmol/L],[(4.8±1.5) ％ vs.(7.6±1.6)％,(7.4±3.2) U/L vs.(23.7±3.0) U/L,(1.5±0.7) vs.(9.9±1.2),respectively,all P＜0.05].Serum osteocalcin concentration was negatively correlated with the levels of FBG,HbAlc,FINS and HOMA-IR in elderly patients with T2DM (r=-0.739,-0.713,-0.613,-0.092,all P＜0.01).Conclusions Serum osteocalcin concentration is correlated with the levels of blood sugar and insulin resistance index in elderly patients with T2DM.A further study on the correlation between osteocalcin and T2DM may provide a new target for the treatment of type 2 diabetes mellitus.