1.Effects of low power microwave on the anomaly of sperm and micronucleus count in marrow polychromatic erythrocytes in rat
Huaming SUN ; Xinan WU ; Jia CAO ;
Journal of Third Military Medical University 2003;0(19):-
Objective To investigate the genetic effect of low power microwave radiation on the anomaly of sperm and micronucleus(MN) formation in the marrow polychromatic erythrocyte (PCE) in rat. Methods Rats were randomly divided into three groups, namely control, experimental group Ⅰ and experimental group Ⅱ. Abnormal sperms and MN formation in marrow PCE were observed and detected after exposure to 1 800 MHz (Continuous wave, CW) microwave radiation for 21 days (12 h/d) with the average power density of 0 mW/cm 2 (control), 0 5 mW/cm 2 (group Ⅰ) and 1 0 mW/cm 2 (group Ⅱ). Results No significant difference in the rate of sperm abnormality and MN formation in marrow PCE was found between the experimental groups and the control. Conclusion No obvious genetic damage caused by low power microwave radiation to the sperm anomaly and MN formation in marrow PCE of rats is found.
2.Evaluated on Expression of Endothelin-3 mRNA Detected by RT-PCR in Acute Pancreatitis Rats
Yong ZHANG ; Yongzhang GUO ; Li LI ; Xinan CAO
Chinese Journal of Bases and Clinics in General Surgery 2003;0(06):-
Objective To investigate the relationship between gene expression of endothelin-3(ET-3) and inflammation of acute pancreatitis(AP) in rats.Methods Fifty-four rats were divided randomly into 4 groups:sham operation group,AP group,arterial injection group and vein injection group.AP was induced by reverse intra-bile duct infusion 4.5% sodium taurocholate,treated with low dose dopamine 〔5 ?g/(kg?min)〕 by injecting arterial or tail vein.Rats were sacrificed at 1,6 and 24 h after the induction of AP.The mRNA expression of ET-3 was evaluated by semi-quantitative reverse transcription-polymerase chain reaction(RT-PCR) and pathological changes was observed in rats.Results Expression of ET-3 mRNA could be detected from 1 up to 24 h after the induction of pancreatitis.Expression of ET-3 mRNA of sham operation group was decreased significantly compared with other three groups.Expression of ET-3 mRNA showed a significant decrease by arterial injection dopamine than that by tail vein(P
3.Augmented renal clearance in Chinese intensive care unit patients after traumatic brain injury: a cross-sectional study.
Zilong DANG ; Hong GUO ; Bin LI ; Maohua ZHEN ; Jian LIU ; Yuhui WEI ; Hongyan QIN ; Zhimin DOU ; Lei ZHANG ; Lei ZHU ; Yongqiang CAO ; Fengjiao LI ; Xinan WU
Chinese Medical Journal 2022;135(6):750-752