Objectives To compare the difference of blood mass spectrometry analysis between decompensated liver cirrhosis patients and compensated liver cirrhosis patients. Methods Thirty-four patients with decompensated liver cirrhosis and 47 patients with compensated liver cirrhosis were selected. All patients were analyzed by blood mass spectrometry, and the detected 93 parameters included amino acids, acylcarnitines and some of their ratios. Results After multivariate analysis using the 93 parameters, the two groups could be differentiated clearly. There were 32 parameters that contributed to the separation, which included 4 ratios. Logistic analysis showed that alanine, tetradecanoyl diacylcarnitine, tetradecenoylcarnitine, proline and serine could be used to separate the two groups sufficiently. Receiver operating characteristic curve analysis indicated that the area under the curve generated using the 5 parameters could reach to 0.99. Except alanine, the other 4 metabolites were all increased in the decompensated patients. Conclusions Blood mass spectrometry analysis could be used to differentiate decompensated and non- decompensated cirrhosis patients. The significantly changed metabolites might provide valuable hint in pathological study of the disease.

OBJECTIVE:To provide reference for breaking the“dual-track”system of the pharmacist and perfecting pharmacist system in China. METHODS:By reviewing laws and regulations relating to the pharmacist in recent 21 years,the implementation and problems of pharmacist system was investigated. RESULTS & CONCLUSIONS:The imperfection and dissonance of pharma-cist management regulations and laws system result in long-term“dual-track”system of pharmacist authentication. There still are other problems such as low rate of pharmacist registration and unbalanced regional distribution;unbalance between national li-censed pharmacist examination and examination condition of health systems pharmacist;divergence and mismatching between phar-macy education pharmacist training;social value of pharmacists cannot be reflected adequately. It is suggested to formulate Regula-tions on the Licensed Pharmacists as soon as possible,establish uniform and standard qualification and title appraisal system for na-tional pharmaceutical professional and technical personnel,promote licensed pharmacist classification registration and examination system reform,strengthen pharmacy education and licensed pharmacist training system reform,guide licensed pharmacist allocation rationally and orderly by various measures and enhance the propaganda of licensed pharmacist and their work,so as to promote the mergence of national licensed pharmacists qualification system and health professional technical pharmacist competence system.

Atrial Fibrillation ; surgery ; Catheter Ablation ; Humans

Atrial Fibrillation ; surgery ; Catheter Ablation ; Humans

Objective: To analyze the regional differences of the health resource allocation in Guangdong Province from 2002 to 2011, and provide the scientific basis for regional health planning and health resource allocation optimizing. Methods: The Theil Index was used to analyze the regional differences of the health resource allocation in Guangdong Province. Results: The health resource per capital is consistent with the national level, while differences existed in different areas, and the gap of the differences has been broaden during this period. Conclusions: The differences are caused by the difference distribution of material resources, human resources, the faulty of system and mechanism. Therefore, the hygienic resources disposition should be balanced establish reasonable mechanism to improve the equity of health human resources, strengthen the community health service as a breakthrough during the health system reform, and promote the equal access to basic medical and health services to narrow the gap of the regional differences and promote the equity of health resource allocation.

Objective To investigate the ideal methods for correction of lower eyelid retraction by lateral canthal anchoring.Methods The authors retrospectively reviewed the records of 126 patients(207 eyelids) operated on between June 1999 and 2005 by one senior surgeon.The age of the patients ranged from 28 to 72 years(mean,46 years).Transcanrhal canthopexy was used in 20 patients(33 eyes);The 3 mm tarsal strip procedure was used in 35 patients(57 eyes);Transcanrhal canthopexy combined with Hamra's lower blepharoplasty was used in 26 patients(45 eyes).The tarsal strip procedure combined with Hamra's procedure was used in 45 patients(72 eyes).75 patients(123 eyes) were followed up for 6～12 months.Mean follow-up time was 8 months. Results Of them,125 patients were uniformly satisfied with their cosmetic and functional outcome at last follow-up;one patient had undercorrection of retraction.There were no major complications and only one minor complications(corneal irritation from graft sutures),which resolved in the early follow-up period.Conclusions The lateral canthal anchoring is an effective,aesthetic,and functional treatment for moderate to severe lower eyelid retraction resulting from multiple causes.This procedure is associated with predictable results,a low morbidity rate,and high patient satisfaction.

Objective:To explore the role of clinical pharmacists in the diagnosis and treatment of drug-induced diseases. Meth-ods:Clinical pharmacists analyzed the abnormal changes in the patients and looked for drug factors during the ward round with physi-cians. Results:Clinical pharmacists found drug-induced diseases and irrational drug use, and proposed the solutions accepted by phy-sicians. Conclusion:Clinical pharmacists should actively participate in the diagnosis and treatment of drug-induced diseases.

OBJECTIVE To explore the information-based management of disposable medical supplies, quality and performance of the medical production. METHODS Combined with successful experience of our hospital, the standardized management of disposable medical supplies in our hospital was introduced. RESULTS Real-time management of using and storage were undertaken to reduce the cost of the hospital. CONCLUSIONS It is available to build digital hospital and realize resources sharing between community hospitals utilizing computer and internet for whole range quality control of disposable medical supplies to obtain economic and social benefits.

OBJECTIVE To guarantee safe use of medical disposables for cure effect and life quality of the patients by tracing the quality of products and the patients lives.METHODS Combining with successful experience of our hospital,the process management for purchase of the disposable medical supplies were introduced.RESULTS By reducing the purchase price of medical consumables,lightening burden of patients,and through public bidding,the price of picked medical consumables was reduced widely.It was benefit to patients.CONCLUSIONS The price of the prodocts is reasonable and quality is reliable.Nevertheless,purchase process of medical consumables need to ameliorate.

Coats disease is a relatively rare and idiopathic disorder characterized by retinal telangiectasia and massive intra-retinal and (or) sub-retinal lipid accumulation, resulting in complications including retinal detachment and neovascular glaucoma. Previous reports have revealed that Coats disease can be associated with other disorders, especially some inherited diseases, such as retinitis pigmentosa (RP) and facioscapulohumeral muscular dystrophy (FSHD). Coats disease associated with other inherited disorders is generally called Coats-like retinopathy, which has some unique features that differs from the classic Coats disease, for example there is no sex and age preference, more bilateral cases, more severe cases and more genetic factors involved. Patients of Coats-like retinopathy with RP and FSHD may have mutations in Crumbs homologue gene 1 and D4Z4 genes.