Erythroblastosis, Fetal ; etiology ; Female ; Humans ; Infant, Newborn ; Rh-Hr Blood-Group System ; immunology

OBJECTIVE: To prepare anti-inflammatory dental ulcer film and establish its quality standard. METHODS: Drug-containing mortar and blank mortar were prepared to prepare compound film agent. HPLC was used to the quantitative analysis of indirubin. RESULTS: The preparation had well appearance and its detection of index was up to the standard stated in Chinese Pharmacopeia. The linear range of indirubin was 0.8～6.4 ?g?mL-1 (r=0.999 8) with an average recovery rate of 100.65% (RSD=1.07%,n=6). CONCLUSION: The formula of preparation is reasonable, the preparation method is simple and applicable and determination method is accurate and reliable.

OBJECTIVE:To evaluate the compatible stability of shuxuening injection with meglumine adenosine cyclophosphate Injection.METHODS:The mixture of shuxuening injection and meglumine adenosine cyclophosphate injection in 5% glucose or 0.9% NaCl injection was investigated in respect of its appearance,particles,pH value and absorbability value,respectively using microscope,pH-meter and UV spectrophotometer.RESULTS:No significant change was noted in appearance,particles,pH value and absorbability value for the mixture at 25 ℃ within 6 h after mixing.CONCLUSION:Shuxuening injection was stable in meglumine adenosine cyclophosphate injection and the two drugs can be mixed to use.

Objective To discuss the treatment effect of doctor-nurse cooperation in multi-plane operation of obstructive sleep apnea hypopnea syndrome.Methods 73 patients with multi-planar surgery due to OSAHS were divided into the observation group (38 cases) and the control group(35 cases) in our department from January 2008 to December 2012.Health care was strengthened throughout the course of treatment in the observation group and traditional treatment and care were adopted in the control group.Short-term and long-term efficacy,intraoperative and postoperative complications were compared between two groups.Results The operation of short-term effective rate was 100％,and significant differences were found in the long-term efficacy between the two groups.There were significant differences in nasal bleeding during surgery,one-time intubation success rate and the significances were found in postoperative pain,extubation time,lung infection and soft palate regurgitation between two groups.Conclusions The implementation of the multi-plane surgery for patients with OSAHS can effectively improve the short-term efficacy of the patients throughout the course of treatment.Strengthening doctor-nurse cooperation effectively improve the patients' long-term efficacy,reducing the patients' intraoperative and postoperative complications.

OBJECTIVE:To provide suggestions for improving the quality of the instructions of domestic generic Levofloxacin injections. METHODS:A set of instructions of original Levofloxacin injection and 20 sets of instructions of domestic generic Levo-floxacin injections(with three kinds of acid radicals)were compared and analyzed in warning,indications,dosage and administra-tion,medication for children,drug interactions,toxicology,pharmacokinetics,etc. RESULTS & CONCLUSIONS:The rate of re-cording indications,dosage and administration and pharmacokinetics among the 21 sets of instructions is high,up to 100%. Among the instructions of domestic generic Levofloxacin hydrochloride injection,Levofloxacin lactate injection and Levofloxacin mesylate injection,the rates of mentioning a tendon injury in the warning section are 30.00%,0 and 33.33% respectively;those of recording antibacterial spectrum in the indications section are 10.00%,0 and 33.33% respectively;those of recording the specif-ic results of drug interactions are 10.00%,0 and 66.67% respectively;and those of recording toxicological information are 70.00%,85.71% and 33.33% respectively,all of which are lower than the recording rates of 100% for the instructions of original one. In the instructions of domestic generic Levofloxacin injection,there is a lack of clinical trial data in the sections of dosage and administration,medication for children and toxicology and of pharmacokinetic parameters for patients with impaired liver/kidney function and special population in the pharmacokinetics section. It is suggested that the manufacturers of domestic generic Levoflox-acin injections should improve the specific contents of the instructions;the instructions regulatory authorities should improve the ad-ministration of instructions examination and approval;and doctors and pharmacists should strictly follow the instructions.

0.05);According to average 15 months follow-up,the complication rate was 0 and the excellent rate of shoulder fuction was 97.1% in the cases fixed with CHP,both were better than those of the cases fixed with K-wire of 38.9% and 72.2% respectively(P

The article introduced advances of pharmacokinetic studies of topiramate, a new antiepileptic agent, in recent years. Topiramate pharmacokinetic parameters were determined after the administrations of single dose, multiple dose and concomitant therapy. The changes of its pharmacokinetic parameters were determined in the influence of the factors, for example, age, disease, and so on. These results have revealed the regulations of metabolism and excretion of topiramate in the healthy volunteers and patients. The data provide a basis of clinical rational medication for the patiens with epilepsy.

To study ecology suitability rank dividing of the total alkaloid content of Coptis Rhizoma for selecting artificial planting base and high-quality industrial raw material in Chongqing province. Based on the investigation of PCB and DEM data of Chongqing province, the relationship between the total alkaloid content in Coptis Rhizoma and topographical conditions was analyzed by statistical analysis. The geographic information systems (GIS)-based assessment and landscape ecological principles were applied to assess eco logy suitability areas of Coptis Rhizoma in Chongqing. slope, aspect and altitude are main topographical factors that affect the content of the total alkaloid content in Coptis Rhizoma The total alkaloid content in Coptis Rhizoma is higher in the lower altitude, shady slope and bigger slope areas. The total alkaloid content is higher in the south areas of Chongqing province and lower in the northeast. Terrain conditions of the southern region of Chongqing are most suitable for The accumulated of total alkaloid Coptis Rhizoma content.
Alkaloids ; analysis ; metabolism ; China ; Coptis ; chemistry ; Ecology ; Environment ; Geographic Information Systems ; Geography ; Plants, Medicinal ; Rhizome ; chemistry

ObjectiveTo survey the social support to students in university.Methods400 college students of grade 2004 from 4 different colleges in Ningbo were tested with the Social Support Rating Scale(SSRS).Results and ConclusionThere were no significant differences among students from Ningbo and students from the other regions.Students from different level colleges had different scores in utilization of support,students from the third level college had the highest scores while students from the forth level had the lowest scores.College students from countries scored higher than students from cities in subjective support,but there were no significant differences in objective support and the utilization of support.Female students had higher scores in subjective support and utilization of support than males while had no significant differences in objective support.Students with different majors had no significant differences in objective support and utilization of support,while concerning subjective support,students from management departments had the highest scores,students from arts departments had the lowest scores.In case of emergency,college students mainly received economic support and mental support from their families,friends and classmates while received less support from various organizations both of colleges and society.

ObjectiveTo investigate the relationship between family cohesion, family adaptability and perceived social support.Methods400 college students of grade 2004 from 4 different colleges of Ningbo were tested with the FACESⅡ-CV and perceived social support scale. Results and ConclusionFamily cohesion and adaptability significantly positively correlated with perceived family support and social support. There was no significant correlation between perceived family support and dissatisfaction with family cohesion, while perceived family support significantly negatively correlated with family adaptability. In family adaptability, dissatisfaction with family cohesion and family adaptability, there were significant differences among students from different level colleges. In perceived family support, there were no significant differences among students from different college. In family cohesion, female students scored higher than male, but showed no significant differences in family adaptability. In perceived family support and social support, female students had higher scores than male were. In family cohesion and perceived family support, fathers' education background but not mothers' had significant main effect. In family cohesion, family adaptability and perceived family and social support, there were no significant differences between students from cities or countries.