Endocardial myocardial biopsy is the gold standard in the diagnosis of viral myocarditis.However,the limitations of sampling to the low sensitivity,and invasive inspection methods limit its clinical application.The traditional diagnostic tool electrocardiography,laboratory values and echocardiography are lack of specificity.Thus,a non-invasive diagnostic approach with high sensitivity is in need.Cardiovascular magnetic resonance(CMR) can evaluate the function of the heart parameters,such as left ventricular function and regional wall motion,and various CMR imagings including T2-weighted imaging,and early- and late-contrast enhanced T1-weighted imaging can evaluate the hyperemia,oedema and necrosis of myocardial inflammation histological character.CMR provides a scientific basis for the diagnosis of viral myocarditis in clinical.

Objective To investigate the relationship between serum surfactant protein-A (SP-A) and -D (SP-D) in patients with systemic lupus erythematosus (SLE) complicated with interstitial lung disease.(SLE-ILD) and its clinical significance.Methods Serum SP-A and SP-D levels of SLE patients and controis were assessed using a sensitive enzyme-linked immunosorbent assay (ELISA).The relationship between SP-A and SP-D and SLE-ILD,the correlation between SP-A and SP-D with age,disease activity index,pulmonary function test and high-resolution computed tomography (HRCT) score were analyzed.Results The level of serum SP-A and SP-D in patients with SLE is higher than that in healthy controls(P＜0.05).The level of serum SP-A and SP-D in patients with SLE complicated with ILD was higher than that in patients without ILD and healthy controls (P＜0.05).The level of serum SP-D in patients with SLE-ILD was correlated positively with HRCT score (r=0.508,P=0.004) and interstitial score (r=0.468,P=0.009),and it correlated inversely with vital capacity (%VC) (r=-0.590,P=0.001 ) and diffusing capacity of carbon monoxide (%DLCO)(r=-0.588,P=0.001 ).There was no correlation between the level of serum SP-A with SLE-ILD and HRCT score,%VC and %DLCO.The level of serum SP-D in patients with SLE-ILD correlated positively with serum IgG (r=0.376,P=0.040),and the level of serum SP-A in patients with SLE-ILD correlated positively with serum C reactive protein (CRP)(r=0.403,P=0.027).There was a positive correlation between the level of serum SP-D in patients with SLE and age (r=0.352,P=O.001 ).Conclusion The levels of serum SP-A and SP-D may be useful markers for ILD in patients with SLE.There is correlation between the level of serum SPD and HRCT score,pulmonary function test,and it is positively correlated with age and disease activity index.

Objective:To elaborate the operation training process and assessment mechanism of medical equipment, emphasizing the medical device operation should be people-oriented, the use of advanced medical equipment must be after through the improvement training and strict examination, adhere to standardized processes, flexible thinking and methods to operating the medical equipment. So that, makes medical equipment to achieve the desired functionality. Methods: By dividing the kind of related personnel of medical equipment, to illustrate the corresponding training and assessment standards level of each staff. Fully mobilize the working enthusiasm of staff, make them pay attention to the normative operation, and change the values of medical equipment for medical staffs, by using the appropriate rewards and punishment system.Results: The medical equipment operation of operating personnel who participate the appropriate training and grade evaluation could conform to the assessment standards. Conclusion: The safety and effectiveness of medical equipment can be effectively improved by upgrade the operating levels of using staffs, it is effectively extending the medical equipment service life and saving the medical equipment cost while upgrading the overall quality of medical cared by the hospital. It makes further sustainable development of hospital.

Objective: To introduce the centralized management method for the conventional medical equipment and its utilization benefits and economic benefits to hospital and clinical department through scientific management pattern. Methods: Through several parts such as utilization ratio, usage cost, daily maintenance, measure control and data analysis, they could explain the advantage and convenience after proceeding centralized management. Results:Reasonable and scientific centralized management pattern could reduce or wipeout the idle and waste phenomenon for conventional medical equipment, reduce the department's expenditure of equipment depreciation, enhance the economic efficiency to hospital and clinical department. Through timely preventive maintenance and measure control, not only could save the precious time for the service staff to share personal experience, enhance the equipment repair time and repair rate effectively, but also could guarantee the equipment operation status and operation stability, protect the safety of patient medical device's usage. Conclusion:By making full use of various valuable data, it could be the reference point for these device's analysis and evaluation. As a result, concluded from economic, safety and scientific research part, it is necessary to promote centralized management for the conventional medical equipment.

Objective To explore the effect and mechanism of aerobic exercise on islet β-cells in type 2 diabetic rats.Methods Thirty healthy SPF 8-week old Wistar rats were randomly divided into control group (C, n=10), diabetic control groups (DMC) and diabetic exercise (DME) groups, 10 rats in each group, among which 7 successful rat models were used in the experiment.The diabetic rat model was established by high fat and sugar diet and i.p.injection of streptozotocin in a dose of 50 mg/kg.The rats of group DME were forced to perform 20 m/min running for 30 min, once a day, 6 days in a week, for 8 weeks.Other rats were allowed free movement.At the end of experiment, serum glucose and insulin were measured and homeostasis model assessment (HOMA) was calculated, and pancreatic tissue samples were collected for histopathological examination.The morphology and structure of pancreatic islets were observed under a digital microscope, the perimeter and area of islets were analyzed by image analysis, and shape factor of islets was calculated.The insulin content, glucokinase and ultramicro-ATPase activity in the pancreatic homogenate were determined.Results In the DME group, the perimeter and area of islets were significantly higher than the DMC group (P< 0.05), but still lower than the control group.The shape factor was significantly increased, the cell hypertrophy, vacuolization and nuclear pyknosis were markedly alleviated than those in the DMC group, the insulin content, glucokinase and the trace total ATP activity in the DME group were significantly higher than those in the DMC group (P<0.05), and the SF and HOMA were significantly changed.Conclusions Aerobic exercise can reduce the blood glucose level, improve the morphology of islets and β-cells in the type 2 diabetic rats.It may be due to increase of the activity of glucose kinase and ATP-synthase, and increased insulin sensitivity in the pancreas.

Objective:To evaluate the effect of segmental approach in the treatment of Angle class Ⅱ division 1 malocclusion.Methods:7 cases of classⅡ,division 1 maloclusion were treated.Upper first premolar and lower second premolars were extracted in all cases.Lower first molars were mesially moved by means of segmental arch. Cephalometric analysis was used to evaluate the effects of the treatment.Results:Facial profile improvement and lower anterior facial height maintenance were achieved.The occlusion plane angle,mandibular plane angle were well controlled with lower anterior teeth upright on the lower basal bone.All patients represented good mandible response.Conclusion:Segmental technique is a simple and effective approach in correcting class Ⅱ,division 1 maloclusion

Diabetic retinopathy ( DR ) is one of the common and serious complications of diabetes, which also the main causes of visual impairment in patients with diabetes, and its incidence has been increasing. With the in- depth study of the pathogenesis of DR, through the control of risk factors including blood glucose, blood pressure and lipid, as well as the application of a variety of drugs, the prevention and cure of DR achieved a certain effect. ln this paper, we make a review of the present status and progress in recent years on the DR control risk factors and drug intervention.

Acoustic Stimulation ; Animals ; Auditory Perception ; physiology ; Behavior, Animal ; physiology ; Noise ; adverse effects ; Rabbits ; Sound ; Swine

Humans ; Noise, Occupational ; adverse effects ; Occupational Exposure ; standards

Objective To explore the value of peak systolic displacement of mitral annulus in evaluating left ventricular systolic function by speckle tracking imaging(STI).Methods The study population consisted of 96 subjects. The apical four-chamber view and two-chamber view were obtained and the systolic displacements of mitral annulus were measured at lateral, spetum, anterior and inferior mitral annulus (MADlat, MADsep, MADant, MADinf).The systolic displacements of mitral annulus midpoint (MADmid) and its ratio to the length of left ventricle at end-diastole(MADmid%) were calculated.Left ventricular ejection fraction(LVEF) was measured by three-dimensional echocardiography.The correlation of these displacements parameter with LVEF was analyzed.Results ① There was no significant difference among MADsep, MADlat, MADant, MADinf and MADmid(P>0.05).②There was significant correlation between LVEF and these parameters (P <0.01) ,and MADmid and MADmid% showed an excellent correlation with LVEF (r = 0.87 and 0.89 respectively, P<0.01).③The cut-off value of MADmid for LVEF>50% was 8.9 mm with a sensitivity of 95% and a specificity of 80% while the cut off value of MADmid% for LVEF>50% was 10.9% with a sensitivity of 95% and a specificity of 85%.Conclusions Displacement of mitral annulus by STI showed an excellent correlation with LVEF, and it may be a new promising method for routine evaluation of left ventricular systolic function with its high feasibility, simplicity and accuracy.