1.Comparison of the effect of strontium-89-chlovide in the treatment of prostate cancer bone metastasis between Uygur and Han people
Ximei FENG ; Shuli GUO ; Yongfang TIAN
Chinese Journal of Primary Medicine and Pharmacy 2013;20(1):13-15
Objective To analyze the effect on prostate cancer bone metastasis of Uygur and Han people treated with strontium-89-chlovide.Methods The curative effects in 36 cases of Uygur and 40 cases of Han patients with prostate cancer bone metastasis were investigated after intravenous injection with strontium-89-chloride,including palliation of pain,change of metastatic focus,level of prostate-specific antigen (PSA) and interleukin-6 (IL-6).Results After treated with strontium-89-chlovide,compared with the han patients with prostate cancer bone metastasis,the palliation rate (83.33 %) F-PSA [(29.29 ± 8.69) μg/L] and T-PSA [(3.73 ± 1.48) ml/L] were higher,the bone metastases and the level of IL-6 were more significantly reduced of Uygur patients,and there were statistically significant (x2 =4.113,t =1.359,t =1.849,all P < 0.05).Conclusion It is more effective treated with 89 SrCl-chloride for the Uygur patients with prostate cancer bone metastasis metastases than the Han patients.
2.Effect of 89SrCl2 for bone metastasis in Uygur and Han patients with prostate cancer
Ximei FENG ; Shuli GUO ; Yongfang TIAN ; Cheng CHEN ; Hongli WANG
Cancer Research and Clinic 2015;27(8):532-534
Objective To analyze contrastly the effect of 89SrCl2 for bone metastasis in Uygur and Han patients with prostate cancer.Methods The curative effects in 75 Uygur and 82 Han patients with prostate cancer bone metastasis were investigated after intravenous injection with 89SrCl2,including palliation of pain.SPECT was used to detect the change of metastasis,level of prostate-specific antigen (PSA) and interleukin-6 (IL-6) were detected by electrochemiluminescence immunoassay.Results After treated with 89SrCl2,the palliation rate,the bone metastases and the level of IL-6 were higher in Uygur patients [82.67 % (62/75),75 % (56/75),(4.24±1.74) pg/ml] than those in Han patients [60.98 % (50/82),52.44 % (43/82),(2.81±2.38) pg/ml],and there were statistically significant (P < 0.05).Conclusion 89SrCl2 is more effective for the Uygur patients with prostate cancer bone metastasis than the Han patients,clinical workers should pay more attention to this.
3.NEUROANATOMY AND SEROTONIN IMMUNOREACTIVITY IN THE BRAIN AND SUBOESOPHAGEAL GANGLION OF THREE BEETLES
Xihan HU ; Ximei TIAN ; Yutang QU ; Zhifu ZHAO ; Tianyi LIU ; Chuantao SONG ; Xuexiang BAO
Chinese Journal of Neuroanatomy 2007;23(5):451-461
The structure and 5-HT immunoreactivity in the brain and suboesophageal ganglion of three beetles, Ambrostoma quadriimpressum, Henosepilachna vigintioctomaculata and Oxycetonia jucunda, were first studied by means of colophony-paraffin embedding serial section technique and strepteavidin-peroxidase immunohistochemical method. The results showed that the brains of these three taxonomically closely related beetles were remarkably different in composition and size. Mushroom bodies and antennal lobes in Oxycetonia jucunda were conspicuous. Calyces and lobes of the mushroom bodies.were much developed. In contrast, calyces of Ambrostoma quadriimpressum and Henosepilachna vigintioctomaculata were extremely undeveloped. However, the postretinal fibres and circumpharyngeal nerves of Ambrostoma quadriimpressum were highly developed. In the three beetles, 5-HT immunoreactivity was present in all neuropils of the brain and the suboesophageal ganglion. The pattern of 5-HT immunoreactivity and the localization of immunoreactive somata which often clustered into groups were similar among these beetles, while the immunoreactivity intensity was distinct, especially in the lamina. The results suggest that the three beetles have given rise to adaptive radiation under the evolutionary pressure because of the long-term different life styles and living environments in which the taxonomic status of Ambrostoma quadriimpressum is relatively low. The similarity of the pattern of 5-HT immunoreactivity and localization of some positive somata among the three beetles raise the possibility that 5-HT seemes to serve similar physiological function in different insects. Furthermore, 5-HT might be involved in modulating the ingestion by regulating muscular activity and visual sensitivity.
4.Effects of dietary approaches to stop hypertension on the quality of life and re-hospitalization rate in patients with chronic heart failure
Lili SUN ; Can ZHANG ; Chunyan MA ; Ximei TIAN
Chinese Journal of Modern Nursing 2018;24(7):822-825
Objective To explore the effects of dietary approaches to stop hypertension (DASH) on the quality of life and re-hospitalization rate in patients with chronic heart failure (CHF). Methods A total of 163 patients with CHF receiving standard medical therapy in the Cardiology Department of the First Affiliated Hospital of Zhengzhou University from February to September 2014 were selected and divided into experimental group (n=85) and control group (n=78) randomly. Low salt, low fat diet was applied in the control group, while DASH was adopted in the experimental group. Patients' body mess index (BMI), blood pressure, blood glucose, blood lipid, ejection fraction, cardiac function, the score of Minnesota Living with Heart Failure Questionnaire (MLHFQ) and re-hospitalization rate were compared before and after intervention. Results There were no statistical differences in BMI, blood pressure, blood glucose, blood lipid, cardiac function and the score of MLHFQ before intervention (P> 0.05). Patients' BMI, systolic pressure, cholesterol and triglyceride of the experimental group paitents were all lower than those of the control group 12 months after intervention, with statistical significance (P< 0.05). 12 months after intervention, patients' quality of life of the experimental group was higher than that of the control group (P<0.05), and the re-hospitalization rate was lower than that of the control group (P<0.05). Conclusions DASH can improve the quality of life in patients with CHF, reduce readmission rate, thus improving the prognosis of heart failure.
5.Correlation between empowerment and professional identity of nurses in Cardiac Intensive Care Unit
Chuyang LI ; Yanyan CUI ; Wei WEI ; Ximei TIAN ; Xiaoping LOU ; Lili XIAO
Chinese Journal of Modern Nursing 2023;29(2):233-236
Objective:To explore the correlation between nurses ' empowerment and professional identity in Cardiac Intensive Care Unit (CCU) . Methods:From June to September 2021, 164 nurses working in CCU of 8 ClassⅢ Grade A hospitals in Zhengzhou were selected as the research object by convenience sampling. The General Information Questionnaire, Professional Identity Scale for Nurses and Empowering Leadership Behavior Scale were used to conduct the questionnaire survey. A total of 164 questionnaires were distributed, and 158 valid questionnaires were recovered, with a valid recovery rate of 96.34% (158/164) .Results:Among 158 CCU nurses, the total scores of the Professional Identity Scale for Nurses and the Empowering Leadership Behavior Scale were (93.24±6.05) and (84.30±7.15) respectively. There was a positive correlation between the total score of Professional Identity Scale for Nurses and the total score of Empowering Leadership Behavior Scale ( P<0.05) . Conclusions:CCU nurses ' professional identity is at the middle level, while empowerment is closely related to their professional identity. Nursing managers should pay attention to the implementation of effective empowerment behavior, improve the professional identity of CCU nurses, and promote the stability of the nursing team.