1.Expression of PTEN in Myocardial Tissue in Coronary Heart Disease
Xuerong LI ; Yong HE ; Yujia LEI ; Xihe QIN ; Qingtao WEI ; Xinmin PAN ; Lijuan LI ; Lin ZHANG
Journal of Forensic Medicine 2016;32(2):94-96,104
Objective To observe the expression of phosphatase and tensin hom ology deleted on chrom o-som e ten (PTEN) in m yocardial tissue in patients w ith coronary heart disease, and explore the relevance betw een the expression of PTEN and the occurrence and developm ent of coronary heart disease. Methods A total of 16 death cases w ith pathological diagnosis of coronary heart disease w ere collected as experi-m ental group, and 19 cases w ithout m yocardial lesions w ere selected as control group. The expression of PTENprotein and its m RNA w ere detected by im m unohistochem istry and real-tim e fluorescence quanti-tative PC R respectively. The correlation betw een the expression of PTEN and the pathogenesis of coronary heart disease w as analyzed. Results The expression of PTENprotein in myocardium in cases w ith coro-nary heart disease w as significantly low er com pared w ith the control group (P<0.05). There w as no sta-tistical difference of the expression of PTEN m RNA betw een experim ental and control group (P>0.05). Conclusion PTEN m ay be involved in the occurrence and developm ent of coronary heart disease.
2. Homosexual behavior and related factors among married men who have sex with men in Mianyang city, Sichuan province
Yi WANG ; Wanming ZHOU ; Jing FAN ; Xihe ZHAO ; Xiaoli WANG ; Chanjuan DU ; Jiang LIU ; Ganjin YANG ; Wei LI ; Xiuwei JIA ; Qin TAN ; Yingwei TIE ; Yanfei REN ; Ping LIAO
Chinese Journal of Epidemiology 2019;40(4):461-465
Objective:
To understand the homosexual behavior and related factors among married MSM in Mianyang city.
Methods:
Between January and October in 2017, a snowball sampling method was adopted to carry out cross-sectional survey through questionnaires plus HIV testing among those MSM in Mianyang city. Logistic regression model was used to analyze homosexual behaviors and related factors among married MSM under study. Statistical analysis was used by EpiData 3.1 and SPSS 19.0 software.
Results:
A total of 234 MSM participated in this survey. The overall rate of homosexual behavior in these married MSM appeared as 94.9