Objective To investigate the prevalence of Parkinson's disease(PD)in a community cohort of elderly in southern Xin Jiang. Methods A total of 6229 residents of Uygurs and Hans ethnicity in Kashi district were investigated from 2008 to 2009 by using a stratified, staged and cluster sampling methods. Results In this study, 57 PD patients were found. The prevalence rate of PD was 0. 7%(21/2871)in Hans and 1.1%(36/3274)in the Uygurs. The prevalence rate of PD increased with age, especially in people aged 85-89 years old. The prevalence rate of PD was 6. 0%(9/150)in illiterate people,followed by 1.0%(30/2968),0. 6%(14/2180)and 0. 5%(4/842)in those having received primary, junior high or senior high school education. Conclusions The prevalence rate of PD increased with age and decreased with education level. There was a correlation between the prevalence of PD and age.

Objective:To analyze the characteristics of elderly patients with moyamoya disease and clinical outcomes after combined revascularization, and to evaluate the safety and efficacy of this method in elderly patients.Methods:Moyamoya disease patients aged 60 years or older who had undergone combined revascularization at the Neurosurgery Center of Aeronautical General Hospital from January 2016 to September 2021 were selected as study subjects.Then patients' clinical data and postoperative complications within two weeks of surgery were collected and a followed-up was conducted.The results were compared with those of previous reports.Results:A total of 46 combined revascularization procedures were carried out in 30 patients.The ages at surgery ranged between 60-75 years, with a mean age of(66.1±4.4)years.The rate of complications within two weeks after surgery was 37%, and the most common complication was speech dysfunction, followed by epilepsy and hyperperfusion.No serious complications such as cerebral hemorrhage and death occurred.The follow-up varied between 3-67 months, with an average follow-up time of(26.8±18.4)months.The MRS score was <3 at 3 months after surgery, and there was no death or severe disability.Conclusions:Perioperative complications in elderly patients with moyamoya disease have a higher incidence rate than in other populations, but patients can usually recover after close perioperative management for 2 weeks.The follow-up has demonstrated that outcomes at 3 months and in longer terms after surgery are satisfactory and clinical symptoms will improve significantly.