The reasons what the phenomenon of Hongbao exist are intricate and complex.The existence of the phenomenon of Hongbao blasphemes against the medical care justice,accelerate the relationship between hospital and patients tension.It will be a fact that the Chinese society unable to radical change in established period.We need to reduce the appearance of the phenomenon of Hongbao as many as possible,and prepare for eliminating the unreasonable and unjust social phenomenon finally.

This paper defines the implication of mutual love between doctors and patients,analyzes the tendency and imperfection in present physician-patient relationship,and points out that the mutual love between doctors and patients is the guarantee for a harmonious physician-patient relationship.It is not only a theoretical ideal,but also a practice of medical service.It holds to propose fair and initiative mutual love between doctors and patients in China,realize general love for all individuals by government,and strengthen the sense of love for others among all ranks of populations.

At present,the relationship between hospitals and patients is becoming increasingly tense,which makes feasible approaches of benignization of the relationship worthy of probing into.The sample survey shows that a doctor or a nurse who is able to win patients'trust should treat patients equally,respect patients'personality,enhance mutual understanding,regard patients as their relatives,possess noble professional morality and foster a nice individual image.

The characteristics and clinical application of the arrival of qi in suspended moxibustion was discussed in this paper. Through literature research and clinical practice, three aspects, including characteristics of arrival of qi in suspended moxibustion, the clinical basis regarding arrival of qi in suspended moxibustion improving therapeutic effects and how to acquire arrival of qi in suspended moxibustion, were discussed to clarify the essential role of arrival of qi in suspended moxibustion as well as its importance to the development of moxibustion medicine. The suspended moxibustion at acupoints could produce arrival of qi similar to acupuncture, which was characterized as non-local or non-superficial heat sensation such as penetrating heat, expanding heat, transmitting heat, even non-hot sensation such as aching, numbing, distending, painful, heavy, cold sensation in the applied region. It is heat-sensitive sensation phenomenon that can improve therapeutic effect in suspended moxibustion.
Acupuncture Points ; Humans ; Moxibustion ; methods ; Qi ; Thermosensing

Drug Discovery ; Humans ; Multiple Myeloma ; drug therapy

BACKGROUND:Demineralized bone matrix as bone tissue engineering biological scaffold material is more researched currently, which has osteoinductive and osteoconductive.
OBTECTIVE:To summarize the development of demineralized bone matrix as bone tissue engineering scaffold material and to prospect its trend.
METHODS:The relative literatures addressing demineralized bone matrix as bone tissue engineering scaffold material published between January 1965 and May 2013 in PubMed database, Chinese Biomedical Database, Wanfang Database and FMJS database were searched by the first author. The key words were“demineralized bone matrix, scaffold material, growth factor, cells, drugs”in English and Chinese. According to the inclusion criteria, repetitive researches were excluded, and final y 34 articles were included.
RESULTS AND CONCLUSION:Scaffold material is the key composition of tissue engineered bone, and only demineralized bone matrix has both osteoinductive and osteoconductive properties which cannot only provide space for bone repair, but also can be combined with bioactive factors, living cells, antibiotics in vitro to construct bone graft thereby promoting healing of bone defects. However, this technique is also facing some problems to be solved such as the ratio of demineralized bone matrix and various substances, disinfection, preservation of osteogenetic activity and antigenicity elimination. Sufficiently understanding demineralized bone matrix as bone tissue engineering scaffold can provide a theoretical basis for its clinical service.

Objective To invetstigate the effects of right stellate ganglion block (SGB) on heart rate variability (HRV) in patients with carbon dioxide pneumoperitoneum.Methods Forty ASA Ⅰ or Ⅱ patients of both sexes,aged 39-75 yr,weighing 47-75 kg,undergoing elective laparoscopic cholecystectomy,were randomly divided into 2 groups ( n =20 each):control group (group C) and right SGB group (group SGB).Right SGB was performed with 1％ lidocaine 7 ml at 10 min before induction of anesthesia.The low frequency power ( LF),high frequency power (HF),total power (TP) and LF/HF ratio were recorded before SGB (baseline,To ),at 5 and 30 min of pneumoperitoneum (T1,2),at 5 min after deflation (T3) and at the end of operation (T4 ).The LF in normalized units (LFnu) and HF in normalized units (HFnu) were calculated.Results Compared with the baseline values at T0,LF,LFnu and LF/HF ratio were significantly increased at T1-4,HF was significantly decreased at T3,4,and HFnu was significantly decreased at T2-4 in group C,and HF was significantly increased at T1-4,HFnu was significantly increased at T2-4 and LF/HF ratio was significantly decreased at T1-4 in group SGB ( P ＜ 0.05 or 0.01 ).LF,LFnu and LF/HF ratio were significantly decreased at T1-4,and HF at T1-4 and HFnu at T2-4 were significantly increased in group SGB as compared with group C ( P ＜ 0.05 or 0.01 ).Conclusion Right SGB can not only inhibit the sympathetic activity induced by carbon dioxide pneumoperitoneum,but also increase the vagal tone.

Literatures available was reviewed on the thrombosis and mechanism of new antithrombotic agents.The pathophysiology of the thrombosis involves dysfunction of endothelium and cell adhesion.The new antithrombotic drugs include factor Ⅹa inhibitors, GPⅡb/Ⅲa receptor blocking agents and the drugs modulating the function of endothelium.

Objective To investigate if the transcription factor Brn 3a can induce committedly ES cells into neurons. Methods pJ5 Brn 3a recombinant expression factors containing objective gene Brn 3a were introduced into mouse ES D3 cells by liposome mediated transfection. The Brn 3a transfected ES cells were cultured to undergo differentiation into neurons. Finally immunohistochemical technique was implied to detect the expression of Brn 3a before and after transfection and some specific marked antigens of mature neural cell and glia cell were detected after the ES cells differentiation into neuron like cells. Results 1 Before transfection ES cells do not express Brn 3a and the Brn 3a immunoreaction is negative. After transfection of Brn 3a gene 24?h the ES cells could be detected to have Brn 3a and the immunoreaction is positive.2 When this Brn 3a transfected ES cells were cultured whithin 1 week over 70% ES cells could differentiate into neuron like cells bearing obvious neurites. These neuron like cells express NF H+L 、 NSE、SY and do not express GFAP.Conclusion Brn 3a transcription factor can successfully induce ES cells to differentiate into neuron like cells. [

Nuclear factor-κB(NF-κB),a transcription factor,which widely exists in neuron,neuroglial cell and vascular endothelial cell.It mainly participates in the inflammatory reaction,apoptosis,immunological reaction and other stress reaction of the body.It is considered as an initiation factot of vascular endothelial cell injury.Cytokines.such as tumor necrosis factor-α may promote the inflammatory cascade reaction in cerebral infarction,and may also play an important role in cerebral ischemic injury.