1.Wisconsin Card Sorting Test and Continue Performance Test in Depression
Zhening LIU ; Junxiong ZHAO ; Xiaozhang CHEN
Chinese Mental Health Journal 2002;0(10):-
Objective: To study the executive and attention function of patients with depression. Methods: We used the Wisconsin Card Sorting Test (WCST) and Continue Performance Test (CPT) to study the executive and attention function in 66 patients with schizophrenia, 42 patients suffering from depression, and 50 normal controls. Results: Schizophrenic patients and depressive patients performed worse than the normal controls in WCST (P
2.Studies on the Chemical Components of Hainanruimu (Kopsia hainanensis)Ⅰ.Isolation and Identification of Monomeric Indole Alkaloids from Its Root
Wenhui YUN ; Yuwu CHEN ; Xiaozhang FENG
Chinese Traditional and Herbal Drugs 1994;0(03):-
From the total alkaloids of the root of Kopsia lainanensis Tsiang, eight compounds were isolatcd and identificd as coronaridine (Ⅰ), heyneaninc (Ⅱ), tabersonine (Ⅲ), 11-methoxytabersonine (Ⅳ), scandine (Ⅴ), N-methoxycarbonyl-11, 12-methylenedioxykopsinaline (Ⅵ), kopsinine (Ⅶ) and N-methoxycarbonyl-12-methoxykopsinaline (Ⅷ) by means of physical constants and spectral analysis
3.Ancient Literature Analysis and Modern Clinical Application of Famous Classical Prescription Zhishi Xiebai Guizhi Tang
Xiaozhang TANG ; Hongxia LIU ; Renwen CHEN ; Xiaodong WANG ; Dasheng LIN
Chinese Journal of Experimental Traditional Medical Formulae 2023;29(8):174-185
Zhishi Xiebai Guizhi Tang, derived from Synopsis of the Golden Chamber (《金匮要略》, Han dynasty, ZHANG Zhongjing), is a famous classical prescription commonly used for chest impediment. By means of bibliometrics, the authors collected 63 ancient Chinese medical books related to Zhishi Xiebai Guizhi Tang and screened 36 effective books for statistical analysis of the historical origin, composition, main indications, dosage, processing, decocting method and other aspects of the prescription. The findings revealed that Zhishi Xiebai Guizhi Tang was composed of five medicinal herbs, namely, Aurantii Fructus Immaturus, Allii Macrostemonis Bulbus, Cinnamomi Ramulus, Magnoliae Officinalis Cortex, and Trichosanthis Fructus, with the function of activating Yang, dissipating mass, dispelling phlegm and lowering Qi. The prescription was mainly used to treat chest impediment, chest fullness, chest pain, wheezing, coughing and shortness of breath caused by suppressed Yang Qi, stagnant heart Qi, stagnant phlegm and stasis, and phlegm evil blocking heart, chest or lungs. Additionally, it was found that there were 70 modern literature recording the clinical applications of Zhishi Xiebai Guizhi Tang, and the main system diseases treated were circulatory system (51, 72.85%), endocrine system (4, 5.7%), respiratory system (9, 12.85%) and digestive system (6, 8.57%), of which circulatory system is dominated by coronary heart disease (chest impediment in traditional Chinese medicine). The involved medical syndrome types mainly included internal obstruction of phlegm heat and turbidity, obstruction of phlegm turbidity and stasis, congealing cold, phlegm, stasis and Qi stagnation, chest Yang depression and combined phlegm and stasis. Ancient medical records and modern clinical application are the keys to ensure the safety and effectiveness of famous classical prescriptions and compound preparations. Therefore, this paper sorted and mined ancient medical books of Zhishi Xiebai Guizhi Tang and statistically analyzed its modern clinical application, aiming to provide a literature reference for the research and development of new drugs and clinical application of the prescription.