1.Study in effect of exercise intervention on the renal transplant recipients during convalescence stage
Chinese Journal of Practical Nursing 2009;25(35):18-21
Objective To explore the effects of exercise nursing intervention on renal transplant recipients.Methods A convenient sample of 64 renal transplant recipients during rehabilitation period were divided into the experimental group and the control group with 32 cases in each group.The experimental group received routine care and rehabilitation exercise,while the control group just received routine care.The body mass index(BMI),blood pressure and heart rate were measured in the two groups.Results Before intervention the differences of BMI,heart rate,blood pressure between the two groups were not statistically significant.However,after intervention,the BMI and blood pressure of the experimental group were lower than those of the control group,but there was no significant differences in heart rate.Conclusions Rehabilitation exercise nursing intervention contributes to raise recipients' quality of life and promote whole rehabilitation.
2.A research about testing the stroke impact scale
Chinese Journal of Practical Nursing 2006;0(10):-
0.5.8 factors can explain the 80% of the whole variable. There were significant differences in the aspects of emotion,ADL/IADL,moving ability,participating and the total score(P
3.Role of dopamine receptor in intestinal mucosal barrier change after brain injury in rats
Chinese Journal of Trauma 2014;30(7):735-739
Objective To investigate the effect of dopamine receptor in intestinal mucosal barrier function after brain injury in rats.Methods Twenty-four rats were allocated to control group,brain injury group,dopamine receptor group,and dopamine antagonist group according to the random number table,with 6 rats per group.Feeney' s weight-drop model was introduced to generate rat models of brain injury.Intestinal mucosal specimens were harvested at postoperative 7 days to evaluate intestinal mucosal morphology by HE staining,expressions of dopamine receptor D1 (DRD1) and dopamine receptor D2 (DRD2) by immunohistochemistry,and mRNA and protein expressions of DRD1 and DRD2 by real-time PCR and Western blot.Meantime,urinary samples were collected to measure lactulose to mannitol ratio (L/M) by high performance liquid chromatography (HPLC).Results Intestinal villus integrity was disrupted in brain injury group and dopamine receptor group when compared to control group,but it remained relatively intact in dopamine antagonist group.Ratio of L/M in brain injury group and dopamine receptor group was similar (0.192 ± 0.080 vs 0.183 ± 0.090,P > 0.05),far higher than 0.037 ± 0.008 in control group (P <0.01),but it was reversed in dopamine antagonist group (0.071 ± 0.008,P < 0.01).Real-time PCR showed DRD1 and DRD2 mRNAs expressed in brain injury group and dopamine receptor group were similar (0.764 ± 0.074 vs 0.718 ± 0.065,0.439 ± 0.051 vs 0.408 ± 0.090,P > 0.05),far higher than 0.189 ± 0.008 and 0.076 ± 0.011 in control group (P < 0.01),but both lowered in dopamine antagonist group (0.386 ± 0.071,0.270 ± 0.092,P < 0.01).estern blot analysis showed DRD1 and DRD2 proteins in brain injury group and dopamine receptor group were similar,but both were far higher when compared to control group (P < 0.01).Conclusion Impaired intestinal mucosal barrier may be relate to the up-regulated dopamine receptor in intestinal mucosa after brain injury in rats.
4.The correlation study between social support for nurses and patients'satisfaction degree with nugsing work
Chinese Journal of Practical Nursing 2008;24(11):1-2
Objective To study the correlation between social support for nurses and patients'satisfaction degree with nursing work.Methods The social support for nurses was evaluated by Xiao Shui-yuan's Social Support Rate Scale(SSRS).The patients'satisfaction degree with nursing work was assessed by self-designed inventory.Results The three dimensions of social support and its total score were positively correlated with patients'satisfaction degree(r=0.21~0.32).Not only the subjective support and patients satisfaction degree with nurses's care but also the objective support and patients satisfaction degree with nurses's knowledge and technique was hishly correlated.The correlation also existed in nursess'utilization degree of social support and patients' satisfaction degree with nurses's knowledge and tech-nique.Conclusion The social support for nurses was correlatd with patients'satisfaction degree with nursing work.Dood social support may contribute to alleviated patients'satisfaction degree
5.Influencial Factors of Quality of Life for Post-stroke Patients
Chinese Journal of Rehabilitation Theory and Practice 2007;13(2):120-121
ObjectiveTo explore the factors influencing quality of life (QOL) in post-stroke patients.MethodsThe data of 76 first-stroke patients in three general hospitals at 1 month and 4 months after stroke were selected with Stroke Impact Scale and analyzed with multiple linear regression.ResultsThe influencing factors of patients' QOL at one months after stroke were education background, type of care, gender, pathological regions, marriage and complications. The education background was the most important influencing factor. The influencing factors of 4 months after stroke were rehabilitation nursing, marriage, social support and gender. Rehabilitation nursing was the most important influencing factor.ConclusionThe many factors influence QOL for post-stroke patients and are changed with time.
6.Influencial Factors of Quality of Life for Post-stroke Patients
Chinese Journal of Rehabilitation Theory and Practice 2007;13(2):120-121
ObjectiveTo explore the factors influencing quality of life (QOL) in post-stroke patients.MethodsThe data of 76 first-stroke patients in three general hospitals at 1 month and 4 months after stroke were selected with Stroke Impact Scale and analyzed with multiple linear regression.ResultsThe influencing factors of patients' QOL at one months after stroke were education background, type of care, gender, pathological regions, marriage and complications. The education background was the most important influencing factor. The influencing factors of 4 months after stroke were rehabilitation nursing, marriage, social support and gender. Rehabilitation nursing was the most important influencing factor.ConclusionThe many factors influence QOL for post-stroke patients and are changed with time.
7.Pharmacokinetics Study of Danshensu in Danqi Injection in Dogs
Yapping JIANG ; Yunfeng ZHENG ; Xiaoying HU
Traditional Chinese Drug Research & Clinical Pharmacology 2000;0(06):-
Objective To study the pharmacokinetics of Danshensu (tanshinol) in Danqi Injection(DQI) in dogs. Methods HPLC-UV detection was used to determine the Danshensu level in biological samples. The Lichrospher C18 column(4.6?250 mm,5?m) was used as an analytical column with a mobile phase consisted of acetonitrile-1 %acetic acid (8∶92),the flow rate being 1.0mL?min-1 and the wave-length being 280 nm. Results After intravenous injection of DQI in dogs,the plasma concentration-time curve of DQI in dogs fitted well to a two-compartment model,with the characteristics of fast absorption and slow elimination.Its pharmacokinetics parameters are as follows:?=1.533 h-1,?=0.5111 h-1,T(peak)=0.25 h,T1/2?=0.573 h. Conclusion The pharmacokinetics of DQI in dogs fits the two-compartment model.In the pharmacokinetics of Danshensu,elimination course is the main course with the slow and lasting characteristics.
8.Intrapericardial injection with a trans-diaphragmatic approach in rats
Haipeng HUI ; Xiaoying LI ; Jiang PENG
Journal of Medical Postgraduates 2003;0(10):-
Objective:To study the feasibility,safety and effectiveness of intrapericardial injection with a trans-diaphragmatic approach in rats and its value in the study of heart diseases. Methods:Blue-black ink,recombinant adeno-associated virus carrying enhanced green fluorescent protein((eGFP)) gene,0.9% sodium chloride solution were respectively injected into pericardium of rats in three different groups(Group ink,Group eGFP and Group sodium chloride) by intrapericardial injection with a trans-diaphragmatic approach.Autopsy was done and hemodynamic parameters were measured and cryosection was analyzed by fluorescence microscopy. Results:The injection was proved successful in all rats in Group ink.Green fluorescence was detected in cryosection of all hearts in Group eGFP and the expression of green fluorescent protein was ubiquitously,but not homongeneous.No rat died during and after the operation among the operated rats(rats in Group eGFP and Group sodium chloride).There was no difference between hemodynamic parameters of the operated rats and those of the controls.Conclusion:The intrapericardial injection with a trans-diaphragmatic approach is a simple,feasible,safe and valid operation and suitable for small experimental animals.And it suggests an easy, safe,efficient and cheap technique in the study of heart diseases.
9.Analysis and countermeasures of the professional psychological pressure of male nursing students
Jihong SONG ; Xiaoying JIANG ; Yaoping CHEN
Chinese Journal of Practical Nursing 2010;26(8):1-4
Objective To analyze the professional psychological pressure and coping style of male nursing students during different learning stage,and discuss effective ways to solve these problems in order to promote physical and mental health development of male nursing students.Methods Using coping style questionnaire and the professional psychological pressure of nursing students questionnaire to survey 102 undergraduate male nursing students from grade 2005 to 2008 of a nursing college of certain province.Results The professional psychological pressure of undergraduate male nursing students was moderate.Male nursing students of different grades had different professional pressure,in which male nursing students of secondyear had lower professional psychological pressure than other students.Manners they adopted to cope with pressure were mature,that is,the "problem-solving-help" approach,in which ways taken by second-year students were more than others.Conclusions Social bias to male nurses should be corrected.Professional psychological education should be carried out to relieve their mental pressure according to characteristics of students in different stage and direct them to realize role change.
10.Effect of hospital disposal manners after the violence on organizational commitment and turnover intention among the head nurses
Ji GAO ; Xiaoying JIANG ; Xuan ZHANG
Chinese Journal of Practical Nursing 2008;24(19):6-8
Objective To study the effect of hospital disposal manners after workplace violence in hos-pital on organizational commitment and turnover intention among the head nurses. Methods Self-made questionnaire about workplace violence in hospital and general condition, organizational commitment question-naire and turnover intention questionnaire were conducted in 122 head nurses who had suffered hospital vio-lence in recent years from all level hospitals of Fujian province. Results The scores of affective commitment and normative commitment of organizational commitment and turnover intention showed significant difference be-tween the groups who suffered positive disposal and who suffered negative interference by the hospital after the violence events (P<0.05), but aggregate score of organizational commitment and the scores of continuance commitment showed no significant difference between the two groups (P>0.05). Hospital disposal manners af-ter the hospital violence and hospital grade were influence factors on turnover intention among the head nurses.Hospital grade was also an influence factor on organizational commitment among the head nurses. Conclu-sions Hospital positive disposal means after the hospital violence on head nurse help to ameliorate organiza-tional commitment and reduce turnover intention among the head nurses.