1.Clinical feature analysis of 24 children with thrombotic microangiopathy
Xiaoying WANG ; Hong GUO ; Xinhui LUO
Chinese Journal of Postgraduates of Medicine 2015;(11):820-823
Objective To explore the clinical feature and therapeutic strategy for children with thrombotic microangiopathy (TMA). Methods The clinical manifestation, auxiliary examination and treatment of 24 cases of children with TMA was analyzed retrospectively. Hemolysis urine toxin syndrome (HUS)occurred in 22 cases, and thrombotic thrombocytopenic purpura (TTP) occurred 2 cases. Results Sixteen cases was onset from May to July,and 8 cases was onset from September to November. Typical HUS (D+HUS) was 8 cases, and atypical HUS (D-HUS) was 14 cases. In 22 HUS children, 18 cases were given hemodialysis or peritoneal dialysis treatment. The illness were significantly improved, and the platelet count and renal function fully recovered normal. But 1 case appeared neurological symptoms such as headache, facial paralysis on one side, gastrointestinal bleeding, and fever, after getting better. Eventually the patient died of disseminated intravascular coagulation. Two cases of TTP were given plasma exchange , anti-infection, large dose of methylprednisolone and anti- platelet aggregation treatment . After treatment, the level of hemoglobin and blood platelets returned normal and consciousness was recuperated. Conclusions HUS and TTP are similar in pathogenesis and clinical manifestation,and it is necessary to be differentiated. Early diagnosis and proper treatment is the key to save the life of children with TMA. As soon as the diagnosis is clear, hemodialysis or peritoneal dialysis treatment should be given to HUS, and plasma exchange to TTP,to quickly control the condition and improve the clinical symptoms.
2.Negative Physical Self of Female Students from 12 to 22 Year-Old
Hong CHEN ; Xiaoying YANG ; Lihong ZHAI
Chinese Mental Health Journal 2002;0(08):-
Objective: To investigate the influence of social comparison and social support on negative physical self of female from adolescents to young adulthood. Methods: 980 female students aged from 12 to 22 completed NPSS-F (negative physical self scale-fatness), MSPSS (multidimensional scale of perceived social support) and PACS (physical appearance comparison scale). Their body mass index (BMI) was also calculated by weight and height of the subjects. Results: High school students had higher score in Fatness dimension than middle school students (13.5?9.3/11.0?9.0,P
3.Models of Eating Disorder Prevention
Rui CHEN ; Hong CHEN ; Xiaoying YANG
Chinese Journal of Clinical Psychology 2000;0(04):-
Eating disorders is a weight and eating related syndrome with cognitive,emotional and behavioral barriers.Prevention of eating disorders is significant.There are three theoretical models on the prevention of eating disorders:non-specific vulnerability-stressor model,social cognitive model,and critical social perspectives model.It's necessary to combine these three models together for effective prevention.
4.Role of social comparison in effet of the mass media on female college students body image
Xiaoying YANG ; Hong CHEN ; Xiao GAO ; Rui CHEN
Chinese Mental Health Journal 2010;24(1):51-54,68
Objective:To research the effect of the media on women's body image.Methods:The subjects were all from 2 colleges.The subjects of experiment 1 were 63 high and low trait social comparison female students.Among them,high trait social comparison subjects were 31 in the model image group,30 in the product image group.Low trait social comparison subjects were 30 in the model image group,32 were in the product image group.The subjects of experiment 2 were the total of 61 high trait social comparison female students.Among them,30 subjects were analyzed by similarity comparison,and 31 subjects received difference comparison.The instruments included advertisement pictures,body image states scale,the physical apperance comparion scale,and the consumer response questionnaire.Results:Analysis of variance showed that,in the model image level,the score of body image scale in high social comparison group was significantly higher than that in low social comparison group [(5.54±1.05)vs.(4.73±0.92),P<0.001].Regression analysis further showed that social comparison was moderator(ΔR~2= 0.035,P<0.01).For social comparisons mode,score of body image scale in difference comparison group was higher than that in similarity comparison group [(5.55±0.82)vs.(4.56±0.86),P<0.05].Conclusion:These findings suggested that social comparison can be used to prevent female college students' negative body images.
5.Relationship between Surface EMG and Angle of Elbow Joint
Xiaoying WU ; Wensheng HOU ; Xiaolin ZHENG ; Hong WANG ; Min ZHA
Space Medicine & Medical Engineering 2006;0(04):-
Objective To explore the correlation between the moving angle of elbow joint and surface electromyogram signal(sEMG)activities of biceps and triceps.Methods The eigenvalue of sEMG during elbow joint moving under constant load were calculated with means of root mean square(RMS)and integrated electromyogram(iEMG)in time domain.Results The experimental results showed that both the chavacteristics of RMS and iEMG for biceps differed from those of triceps.The sEMG activities of biceps increased with the increment of elbow joint angle,while those from triceps reached to the maximum values when elbow joint angle was 90?.Furthermore,the sEMG activities of triceps at the elbow angle of 45? was similar with that when elbow angle was 135?.Conclusion The sEMG from biceps and triceps can reflect the moving angle of elbow joint under constant load.
6.The Clinical Effect of Conjunctival Sac Artificial Eye in Stimulating the Growth of Orbital and Conjunctival Sac
Xiaoying LIU ; Hong ZHANG ; Jianshu KANG ; Zhulin HU
Journal of Kunming Medical University 2013;(12):40-43
Objective To observe the clinical effect oflamellar keratectomy+conjunctival flap+implanted artificial eyein stimulating the orbital and conjunctival sac growth. Methods A retrospective case study: 12 cases (12 eyes) with congenital microphthalmos in the Fourth Affiliated Hospital of Kunming Medical University in 2009-2013 were selected. In these cases, there were 11 cases of microphthalmos, and 1 patient due to congenital absence of the eye without surgery, were given direct implant of the artificial eye;7 patients without significant stenosis in conjunctival sac,received thelamellar keratectomy+conjunctival Flap+implantation of artificial eye, 4 patients with conjunctival sac stenosis recieved thelamellar keratectomy+conjunctival flap+implanted artificial eye+eyelid suture. Results For stunted children who couldn't wear a prosthetic eye, after treated withlamellar keratectomy + conjunctival flap + artificial eye implantation, the conjunctival sac developed well, cornea was covered with conjunctiva well and no exposure,the appearance and volume of orbit was also improved. ConclusionLamellar keratectomy+conjunctival flap+artificial eye implantsurgery is an effective way to promote orbital and conjunctival sac development of the children with congenital microphthalmos.
7.Low-frequency hippocampal stimulation increases the extracellular γ-aminobutyrate level in the brain, inhibits the epileptic seizures and after discharges of the amygdala in pharmacoresistant temporal lobe epileptic rats
Guofeng WU ; Xiaoying LIU ; Zhen HONG ; Taifeng TANG
Chinese Journal of Neurology 2014;47(8):542-547
Objective To establish a multi-drug resistant model of temporal lobe epilepsy and observe the effect of hippocampal stimulation on pharmacoresistant epileptic rats and its possible mechanism with the use of indexes including after discharges (AD) of the amygdalae,the stimulus-induced seizures and the extracellular levels of γ-aminobutyrate (GABA).Methods Totally,120 Wistar rats were used for the amygdaloid kindled model of epilepsy by chronic stimulation of amygaloid basal lateral nucleus.Based on the successful kindled model of epilepsy,we selected the pharmacoresistant and pharmacosensitive epileptic rats according to their response to phenobabital and phenytoin.We then divided the pharmacoresistant epileptic rats into the hippocampal stimulation group and control group,with 8 rats in each group.Low-frequency stimulus was conducted for two weeks in the hippocampal stimulation group.The hippocampus extracellular fluid collected by microdialysis was then used to determine the levels of GABA by a high performance liquid chromatography method after hippocampal stimulation.Results The stimulus-induced seizures were inhibited significantly,and the frequency of the AD was decreased,as well as the amplitude,compared with the control group.The extracellular level of GABA in the 8:00-9:00 am and the 8:00-9:00 pm was (32.69 ± 7.80) and (35.76 ± 6.27) μg/ml,respectively,both significantly increased as compared with the control ((26.58 ± 6.87) μg/ml,t =-21.45,P =0.000 ; (31.50 ± 4.87) μg/ml,t =-15.74,P =0.000).Conclusions The low-frequency hippocampal stimulation inhibits the seizures of the kindled model of epilepsy and decreases the frequency,the amplitude,as well as the duration of the amygdale AD in the pharmacoresistant epileptic rats,which may be contributed to the increased GABA content in extracellular fluid of the brain after stimulation.
8.Application of emergency nursing professional team in the pre-hospital care
Xiaoying HONG ; Na LI ; Ling ZHOU ; Genqun WANG ; Chaoying HUANG
Modern Clinical Nursing 2013;(3):51-53
Objective To study the role of emergency nursing professional team in the pre-hospital care.Methods Two hundred patients from October 2011 to March 2012 were set as the control group and another 200 patients from April 2012 to September 2012 were selected as the experiment group.The control group was managed by routine emergency mode and the experiment group by the emergency nursing professional team.The two groups were compared in terms of satisfaction degree,the time for the team to start and the rate of adverse nursing events.Results After establishing the emergency nursing professional team,the satisfaction degree was significantly increased,the time for the team to start was significantly shortened and the rate of adverse nursing events was significantly decreased(all P<0.05).Conclusion The management mode of emergency nursing professional team in pre-hospital medical care can effectively improve the quality of nursing care.
9.Anesthetic choice for patients undergoing cesarean section complicated with placenta implantation
Yang WANG ; Hong ZENG ; Xiangyang GUO ; Xiaoying RONG
Journal of Peking University(Health Sciences) 2017;49(2):322-325
Objective:To investigate the anesthetic choice for patients undergoing cesarean section complicated with placenta implantation.Methods: A retrospective case review of the patients with placenta implantation between 2008 and 2013 at Peking University Third Hospital was conducted in the International Classification of Diseases (ICD)-9 codes,excluding natural birth and not first diagnosed in our hospital,a total of 96 cases were incorporated into this study.According to the degree of implantation,they were divided into three groups: accreta group,increta group and percreta group.We analyzed the time from the start of surgery to baby delivery and the anesthetic technique.Results: The accreta group included 49 cases,the increta group 33 cases,and the percreta group 14 cases.The average time from the start of surgery to fetus delivery in the three groups were (6.7±3.0) min,(7.2±4.6) min,and (11.9±4.9) min,and the percreta group was significantly different from the accreta group and the increta group (P<0.05).There were significant differences among the three groups in anesthetic choices (P<0.001): in the accreta group,45 cases (91.8%) underwent spinal anesthesia,2 cases (4.1%) underwent general anesthesia,and 2 cases (4.1%) were converted to general anesthesia after spinal anesthesia during the operation;in the increta group,22 cases (66.7%) underwent spinal anesthesia,4 cases (12.1%) underwent general anesthesia,and 7 cases(21.2%) were converted to general anesthesia after spinal anesthesia;in the percreta group,2 cases (14.3%) underwent spinal anesthesia,2 cases (14.3%) underwent general anesthesia,and 10 cases (71.4%) were converted to general anesthesia after spinal anesthesia.Conclusion: Spinal anesthesia can be used as the first choice of cesarean section complicated with placenta implantation and general anesthesia should be considered in placenta percreta.
10.Application of intraoperative cell salvage combined with leukocyte depletion filter on radical nephrectomy for renal carcinoma with inferior vena cava tumor thrombus:2 case reports
Hong ZENG ; Xiaoying RONG ; Xiaoqing ZHANG ; Xiangyang GUO
Journal of Peking University(Health Sciences) 2017;49(4):736-739
Intraoperative cell salvage (IOCS) has been widely used to reduce allogeneic blood transfusion and prevent blood transfusion related complications during surgery.However, due to the risk of transfusion related reaction, contamination, and immunological reaction, its use for tumor patients has been controversial and limited.To explore the feasibility of the application of IOCS in cancer patients, we reported 2 cases of renal cell carcinoma (RCC) with tumor embolism in IVC that underwent radical nephrectomy,and inferior caval venous thrombectomy receiving IOCS combined with leukocyte depletion filter (LDF) from August 2016 to November 2016 in our hospital.The cell saver blood salvage (Haemone-tics, 5+) was used for these 2 cases.The salvaged blood was filtered through the LDF before infusion.For case 1 (male 45-year-old) the total operation time was 505 min, and the estimated blood loss was 4 500 ml.A total of 1 000 mL autologous blood, 12 u allogeneic packed red blood cells (PRBC), 1 200 mL fresh frozen plasma (FFP) were infused during the procedure.The patient was discharged from hospital after 75 days without complications.The postoperative follow-up for 3 months showed no tumor recurrence or metastasis.For case 2 (a male patient, aged 51 years), the total operation time was 490 min, and the estimated (blood loss was 7 000 mL.the patient received 2 700 mL autologous blood transfusion, 12 u allogeneic packed red blood cells (PRBC), and 2 400 mL fresh frozen plasma (FFP).The patient was discharged from hospital after 86 days without severe complications.the postoperative follow-up for 6 months showed no tumor recurrence or metastasis for this patient.Other relevant retrospective studies with this technique showed that cell salvage could be used safely in many kinds of cancer patients, for example, bladder cancer, liver cancer and kidney cancer.Furthermore,numerous researches have proved the safety and efficacy of the combination of these two techniques, the intraoperative cell salvage technique and leucocyte depletion filter in cancer patients.Here we only reported two cases using IOCS and LDF.Further work is needed to determine whether the use of intraoperative cell salvage combined with leukocyte depletion filter can be used safely for patients with HCC.