1.Application of "people oriented" concept to construction of teacher's team in university
Chinese Journal of Medical Science Research Management 2008;21(6):356-358
The author described the application of "people oriented" management concept to the construction of teacher's team of the university in four aspects:talent recruitment;the stability and the sustainable development of current team:the management of teacher's team,the rationalization of incentive mechanism.And the author also put forward some corresponding proposal and solution in the construction of teacher's team of the university.
2.On the Psychological Adaptation of Medical Freshmen
Chinese Medical Ethics 1994;0(06):-
As the particular "post-1990's generation's" entry to college,the psychological adaptation of medical freshmen is drawing more and more attention from each corner of colleges and the general public.This paper analyzes current issues in the psychological adaptation of medical freshmen and comes up with corresponding countermeasures,so as to improve the psychological quality and adaptability for medical freshmen.
3.Correlation study of MMP-9 and TIMP-1 with hemorrheology in male patients with diabetic cerebral infarction
International Journal of Laboratory Medicine 2014;(12):1583-1584,1587
Objective To investigate the correlation of matrix metallopeptidase-9 (MMP-9 )and tissue inhibitor of metalloprotei-nase-1(TIMP-1)with hemorrheology in male patients with diabetic cerebral infarction.Methods 56 patients with type 2 diabetic cerebral infarction(group A),49 cases with non-diabetic cerebral infarction(group B),and 40 cases of community healthy men (group C)were enrolled in the study.The serum levels of MMP-9 and TIMP-1 and hemorrheology indexes were detected.Results The levels of MMP-9 and MMP-9/TIMP-1 in group A were significantly higher than those in group B and C(P<0.05),however, TIMP-1 level in group A was significantly lower than that of group C(P<0.05).The levels of MMP-9 and MMP-9/TIMP-1 in group B existed significant increasing,compared with group C(P<0.05).The levels of high shear viscosity,plasma viscosity,and platelet aggregation index in group A were significantly higher than those in group B and C(P<0.05).While the levels of low shear viscosity,plasma specific viscosity,and platelet aggregation index showed significant differences between group B and C(P<0.05). MMP-9 positively correlated with high shear viscosity,plasma specific viscosity,and platelet aggregation index(P<0.05).TIMP-1 negatively correlated with high shear viscosity and plasma ratio viscosity(P<0.05).And MMP-9/TIMP-1 showed significant cor-relation with high shear viscosity,low shear viscosity,plasma specific viscosity,and platelet aggregation index(P<0.05).Conclusion In patients with diabetic cerebral infarction,MMP-9,TIMP-1 and their ratio show some correlation with hemorrheology indexes. Detecting these indexes would be helpful for the diagnosis of diabetic cerebral infarction.
4.Investigation of the role of health education in hypertension treatment
Chinese Medical Ethics 1994;0(06):-
The author has done a clinical trial of health education project in 53 cases of mild or moderate hypertension patients aged 35-75 years.He investigates and compares the differences of patients' awareness of the disease,compliance of doctor's advice,control of blood pressure before and after the implementation of health education,then discusses the role of health education in hypertension treatment and puts forward several medical ethical issues existed in the treatment of hypertension.
5.Study on p53 codon 72 polymorphism in patients with breast cancer
Cancer Research and Clinic 2011;23(9):646-648
Breast cancer is the most frequent malignant tumors in women,The p53 gene is found to be one of the most closely associated tumor-suppressor genes in human malignant tumors.Some studies have shown an association between polymorphisms at the forth exon (codon 72) and human malignancies recently.At present, the domestic investigations concerned the p53 polymorphisms mainly in lung cancer, uterocervical cancer,esophagus cancer,ovarian cancers,but the studies in breast cancer are rare in domestic.The correlation between the genotypes of p53 codon 72 polymorphism and breast cancer were reported.
6.More attention should be paid to metabolic disorders in polycystic ovary syndrome
Chinese Journal of Endocrinology and Metabolism 2010;26(5):349-350
The prevalence of polycystic ovary syndrome (PCOS) in fertile aged women is about 6%. Many studies show that insulin resistance in PCOS is closely associated with metabolic disorders, which may even potentially increases the risk for cardiovascular diseases. Therefore, metabolic disorders in PCOS should be controlled more actively.
7.How to correctly understand the effect of metformin in the treatment of polycystic ovary syndrome
Chinese Journal of Endocrinology and Metabolism 2012;28(8):609-610
Metformin has been used in treating the patients with polycystic ovary syndrome (PCOS) for more than a decade.This article discusses its effect on the improvement of ovulation and hyperandrogenemia.
8.Efficacy and safety of neural stem cell transplantation for the treatment of Parkinson’s disease
Chinese Journal of Tissue Engineering Research 2013;(27):5033-5040
BACKGROUND: At present, the clinical application of amplified neural stem cells in the treatment of nervous system diseases is stil in exploratory stage. OBJECTIVE: To investigate efficacy and safety of neural stem cel transplantation for the treatment of Parkinson’s disease. METHODS: The embryonic brain tissues aged 12 weeks were obtained for proliferation in vitro, then the brain tissues (5×106-2×107) were prepared into the 4-6 mL suspension. The suspension was injected into 30 cases of Parkinson’s disease through lumbar puncture and carotid injection, once a week, continuously for 3 weeks. Unified Parkinson’s disease rating scale, Hoehn-Yahr scale and Schwab & England Activities of Daily Living Scale scoring were performed prior to and after transplantation. Blood and urine routine, liver function, renal function and adverse reactions were detected and evaluated prior to and after transplantation. RESUTLS AND CONCLUSION: The 12-week-old embryos cultured neural stem cells could be stably amplified in vitro with the capacities of differentiation into neurons, astrocytes and oligodendrocytes. The fol ow-up results showed that neural stem cel transplantation could effectively control the pathological process of Parkinson’s disease, restore the damaged brain function, and improve the patient’s neurological function without significant complications. It is feasible and effective to use the in vitro long-term amplified human neural stem cel transplantation in the treatment of Parkinson’s disease.
9.Viewing at use of glucagon-like peptide-1 in treatment of type 2 diabetes based on the secretion characters of incretins
Chinese Journal of Endocrinology and Metabolism 2011;27(4):后插1-后插4
Recently, in the field of pathogenesis and treatment of type 2 diabetes, incretin is a major breakthrough. Based on the knowledge about physiological mechanism, pathological characters, and clinical application, this review article summarized the mechanism of nutrients ( glucose, fat, and protein) mediated incretin secretion, the impairment of incretin secretion and action in type 2 diabetes and glucagon-like peptide-1 's use in type 2 diabetic patients.
10.The Challenges and Countermeasures on Modern Females Participation in Higher Education
Chinese Journal of Medical Education Research 2003;0(02):-
In modern society, the females have made great progress in participating in higher education, but they are still faced withrigorous challenges, which are from their own ideas, the traditional social custom, the country's relative policies and stipulation and thesmall environments of colleges and universities of higher learning. Colleges and universities of higher learning are responsible for theimportant task of cultivating the high quality female talents. The sustainable development of high quality female talents is especiallyimportant. So, some countermeasure suggestions given in the article are expected to be attached importance to by decision-makingdepartments.