1.Eye Movement Research on Comprehension Monitoring in Reading between Students with and without Hearing Impairment
Xiaoming LIU ; Xiaoxin DU ; Tianlong QIU
Chinese Journal of Rehabilitation Theory and Practice 2014;(6):548-553
Objective To compare the comprehension monitoring in reading between students with and without hearing impairment. Methods An error detection paradigm and an eye-movement recordings method were used in two samples of hearing impairment students and no-hearing impairment students with passages that contained inconsistencies with interval 2 sentences, 4 sentences, 6 sentences and 8 sentences. Results The scores of reading comprehension, the index of tradition monitoring and the index of eye movement were lower in the hearing impairment students than in the no-hearing impairment students (P<0.05). Conclusion The comprehension monitoring ability in reading is poor in the hearing impairment students.
2.Clinical characteristics of diabetes mellitus in Morindawa Daur population
Yan WANG ; Nailin CHEN ; Zhan YANG ; Xiaoxin SUN ; Shiyu WANG ; Wei QIU ; Peng ZHOU
Chinese Journal of General Practitioners 2015;14(9):698-700
Total 967 patients with diabetes mellitus treated in Morindawa People's Hospital from June 2012 to June 2014 were included in the study,among them 425 (44.0%) were of Daur nationality and 542 (56.0%) were of Han nationality.The clinical data and laboratory tests were analyzed and compared between two groups.Compared with Han nationality,Daur patients presented a younger average age[(55 ± 1 1) y vs.(58 ± 1 0) y,P=0.000],an earlier age of onset[(50±10)y vs.(53 ± 1 1) y,P=0.000],a higher percentage of males (54.8% vs.46.9%,P =0.008),a higher percentage of rural residents (42.1% vs.36.2%,P =0.034),a lower level of fasting blood-glucose (FBG) [(9.25 ± 3.37) mmol/L vs.(10.28 ±4.33) mmol/L,P =0.000],higher levels of HbA1c [(7.61 ± 1.71)% vs.(7.29 ± 1.63)%,P=0.008],triglyceride (TG) [(2.91 ±2.06) mmol/L vs.(2.36 ±2.13) mmol/L,P =0.008],low density lipoprotein cholesterol (LDL-C) [(3.22 ± 1.06) mmol/L vs.(3.01 ±0.92)mmol/L,P=0.020],systolic blood pressure (SBP) [(139.48 ± 21.58) mmHg (1 mmHg =0.133 kPa) vs.(136.37 ± 23.44) mmHg,P =0.002],diastolic blood pressure (DBP) [(87.23 ± 12.59) mmHg vs.(85.32 ± 12.52) mmHg,P =0.019],blood uric acid [(324.97 ± 106.45) μmol/L vs.(285.32 ± 98.69) μmol/L,P =0.000] and the ratio of urine microalbumin to urine creatinine [(2.29 ±5.57) mg/g vs.(0.12 ±0.98) mg/g,P =0.000].The results show that Daur diabetic patients are.younger in age,with more severe disorders in HbA1 c,blood pressure,blood uric acid and lipids levels,which increase the probability of renal damage or cardiovascular diseases in these patients.
3.Utilization of and satisfaction at community health service:Comparative analysis between mi-grant workers and non-migrant workers in Shenzhen
Hongrui WANG ; Chuangliang QIU ; Jian DENG ; Yanfeng ZHOU ; Liqing LI ; Xiaoxin DONG ; Zuxun LU
Chinese Journal of Health Policy 2016;9(2):31-35
Objective:To explore the utilization of and satisfaction at community health service between migrant and non-migrant workers in Shenzhen city. Methods: Random sampling was used and 8000 community residents in Shenzhen city were investigated, and the data was analyzed with SPSS 18. 0. Results:There was statistically signifi-cant difference on the times of seeking community health services last year between migrant workers and non-migrant workers ( P<0. 0001 ) , and the proportion of more than three times service utilization of migrant workers were greater than that of non-migrant workers. The top three elements inpluencing satisfaction at community health service between migrant and non-migrant workers were service attitude ( 73. 29% vs. 73. 46%) , technical level ( 65. 29% vs. 67. 50%), and its convenience of seeking a doctor (63. 16% vs. 64. 98%). 73. 47% of users (migrant workers:74. 16%, non-migrant workers:69. 71%) were willing to accept the system of first contact in community health in-stitutions. Conclusions:The utilization of community health service has increased since implementing the system of first contact in community health institutions. Both migrant workers and non-migrant workers were very satisfied with the community health services, and the differences on satisfaction between the two groups were not significant. It is feasible to gradually promote the system of first contact in community health institutions over China.
4.Inhibitory effects of cyclooxygenase-2 inhibitor and α-interferon on growth of human liver cancer xenografts and tumor angiogenesis in nude mice
Chaohui ZUO ; Xiaoxin QIU ; Jinguan LIN ; Hua XIAO ; Junjun LI ; Hu QUAN ; Haizhen ZHU
Chinese Journal of General Surgery 2013;28(12):956-960
Objective To investigate α-interferon (α-IFN) and cyclooxygenase-2 (COX-2)inhibitor celecoxib synergistically inhibit the growth of human liver cancer SMMC-7721 cells xenografts and tumor angiogenesis in a nude mouse model.Methods The effects of celecoxib and α-interferon on tumor volumes and weight were observed.The expressions of VEGF and Cox-2 were determined by immunohistochemistry and RT-PCR,and the effect of α-interferon on MVD also was observed by immunohisto chemistry.Results During the period of observation tumor volume increased progressively in control group,while it was suppressed obviously in other drug treatment groups.The average tumor volume was significantly smaller in celecoxib + α-IFN group than that in IFN group,celecoxib group and control group (P < 0.01,respectively),its inhibitory rate was 61.84%.Immunohistochemistry showes that the VEGF and MVD was significantly smaller in celecoxib + IFN group than that in α-IFN group,celecoxib group and control group (P < 0.01,respectively).RT-PCR shows that the COX-2mRNA and VEGF mRNA pression was lower in the celecoxib + α-IFN group than in α-IFN group,celecoxib group and control group (P < 0.01).Conclusions The COX-2 inhibitor celecoxib and α-interferon synergistically reduces xenografts growth of human liver cancer SMMC-7721 cells effectively via suppressing tumor growth and angiogenesis.
5.Standardized Operational Protocol for Human Brain Banking in China.
Wenying QIU ; Hanlin ZHANG ; Aimin BAO ; Keqing ZHU ; Yue HUANG ; Xiaoxin YAN ; Jing ZHANG ; Chunjiu ZHONG ; Yong SHEN ; Jiangning ZHOU ; Xiaoying ZHENG ; Liwei ZHANG ; Yousheng SHU ; Beisha TANG ; Zhenxin ZHANG ; Gang WANG ; Ren ZHOU ; Bing SUN ; Changlin GONG ; Shumin DUAN ; Chao MA
Neuroscience Bulletin 2019;35(2):270-276
Brain
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pathology
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China
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Humans
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Organ Preservation
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standards
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Tissue Banks
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ethics
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standards