1.Effect of Yangyinqingfei granula on immune function in mycoplasma pneumonia complicated with Epstein-Barr virus of children
Chinese Journal of Biochemical Pharmaceutics 2016;36(6):155-157
Objective To investigate the effect of Yangyinqingfei granula on immune function in the treatment of mycoplasma pneumonia complicated with Epstein-Barr virus of children.Methods 108 mycoplasma pneumonia complicated with Epstein-Barr virus of children from our hospital were selected and randomly divided into two groups.The control group of 54 cases were treated by simple western medicine treatment and the experimental group of 54 cases were treated on the basis of the control group with Yangyinqingfei granula.The improvement of clinical symptoms, inflammation indexes and the levels of T lymphocyte subsets, clinical efficacy and complications were compared.Results The clinical efficacy in experimental group was 90.74%,which was significant higher than that in control group 75.93%(P <0.05).Compared with the control group,the remission duration of fever, cough and rales,the disappearance time of lung X-ray,the length of stay were shorter(P<0.05), the CRP,IL-6,TNF-αand IL-8 levels were lower ( P <0.05 ) , the CD3 +, CD4 +, CD4 +/CD8 + and NK levels were higher, the CD8 +level was lower ( P <0.05 ) . Conclusion Yangyinqingfei granula could reduce the inflammatory factors and improve immune function in the treatment of mycoplasma pneumonia complicated with Epstein Barr virus infection pneumonia in children.
2.The Experience of Teaching International Students' Physiology
Chinese Journal of Medical Education Research 2006;0(08):-
Aiming to improve the quality of teaching international students and enhance the international cooperation of medical teaching,this article discusses the teaching to international students from the aspects such as enhancing the recognition,breaking through language communication obstacles,careful preparation and teaching,and strict regular management by combining practice and research obtained from recent years of international student teaching.
3.The relationship among big five-personality, resilience and general health of new recruits
Xiaoxia CHEN ; Mingjie ZHOU ; Jianxin ZHANG
Chinese Journal of Behavioral Medicine and Brain Science 2011;20(6):547-548
Objective To discuss the relationship among Big Five-Personality, Resilience and General Health of the new recruits in a certain troop. Methods 205 new recruits completed the questionnaires, which include NEO Five-Factor Inventory ( NEO-FFI) , Connor-Davidso Resilience Meter (Chinese version) , and General Health Questionnaire (GHQ-12). Results The neuroticism trait of personality positively correlated to General Health( r = 0.50, P<0.001) and significantly predicted mental disease (β =0.4, P<0.01). The self-strengthening dimension of resilience was negatively related to general health ( r = - 0. 51 , P<0. 01 ). Furthermore, self-strengthening played partial mediating role between neuroticism and general health ( Sobel Z =2. 92, P<0. 01). Conclusion The neuroticism trait of personality is a risk factor for new recruits'mental health, while self-strengthening is a protective factor for it.
4.Application and exploration of the pervasive teaching method in medical humanity education
Tao YANG ; Xiaoxia CHEN ; Jingjing TIAN
Chinese Journal of Medical Education Research 2012;11(3):255-257
ObjectiveTo explore an effective educational method of medical humanity to improve the medical humanistic quality for nursing students and to lay a basis for the culture of medical personnel with high-quality.MethodsTwo classes of nursing students in grade 2010 were selected randomly and divided into the control group ( CG,n=65 ) and the experimental group ( EG,n=62 ).Personnel training project of our school was applied in the control group including the teaching of compulsory basis medical humanity courses:medical psychology,interpersonal communication,medical ethics and laws from the first semester to the third semester after entering the school.The pervasive teaching method was used in the EG.The basic content of humanistic quality,education was integrated systematically into the teaching of every course,class and extra-curricular activity in a planned way.The check on the topic of etiquette,verbal expression and communication and psychological quality ( the full mark of each topic was 10 points ) was conducted in the third semester in the two groups.The average points of the three topics were graded as the students' final mark of this course.T-test analysis on students' mark of each subject was used.Results The result of t-test showed that the marks of etiquette and psychological quality in EG were obviously higher than those in CG ( P<0.05 ),however,no statistic difference in speech communication and expression was observed.ConclusionThe pervasive teaching method is beneficial to students concerning the accepting,understanding,digesting and absorbing of medical humanity knowledge can it can effectively enhance the humanistic quality of medical students.
5.The Priming Effects of Knowledge Representation of Chinese- English Bilinguals
Weizhi LIU ; Guanghui DENG ; Xiaoxia CHEN
Chinese Journal of Clinical Psychology 2001;0(03):-
Objective: To explore how the Chinese- English Bilinguals represent knowledge of the second language. Methods: The inter- language priming effects were investigated in two priming- category judgement tasks based individual- ly on the semantic (ExperimentⅠand ExperimentⅡ) and phonological information (ExperimentⅢ and ExperimentⅣ). Re- sults: In experimentⅠand ExperimentⅡ, no matter what the relation between the English targets and the English primes was semantic association or homophones and similar phones, the significant priming effects were obtained; However, In the experimentⅢ, when the relation between the targets and the primes was semantic association, no significant priming effect was found; In experimentⅣ, when the relation was homophones and similar phones, the significant priming effects were obtained. Conclusion: ①The second language knowledge of Chinese- English Bilinguals was represented in the semantic and phonological characters; ②The conceptual representation could be discreted with the lexical representation.
6.Study of the brain development in infants of diabetic mother
Xiaoxia CHEN ; Congle ZHOU ; Hongmei WANG
Chinese Journal of Perinatal Medicine 2003;0(05):-
Objective To study the brain development in infants of diabetic mother. Methods The development of cerebral grey matters and white matters was evaluated in 64 infants of pregnant diabetic mother by echoencephalography and medical image analysis system. The parameters were compared with 101 infants of non-diabetic mother. The early brain response function of newborns was assessed. The neurodevelopment after neonatal period was also evaluated. Results The brain in infants of diabetic mathers was immature.The average values of grey density in thalami (76.92?6.60) were significantly lower in full term infants of diabetic mathers than that of the infants of non-diabetic mathers (84.72?6.35). These were also obvious in white matters of frontal lobe [(62.68?5.21) vs (67.60?4.09)] and occipital lobe [(73.39?5.67) vs (78.61?2.95)] (P
7.A clinicopathological study of Alport syndrome and detection of type Ⅳ collagen chains in Alport patients
Nan CHEN ; Xiaoxia PAN ; Hong REN
Chinese Journal of Nephrology 1994;0(04):-
Objective To analyse the clinicopathological changes of Alport syndrome (AS) and to detect the deposition of type Ⅳ collagen within basement membrane of Alport patients. Methods Fourteen patients with AS (12 families) hospitalized from 1990. 1 to 1996. 6 were investigated. Eleven were male and 3 female (mean age 29. 4 years). Results Microscopic hematuria was found in 13, with recurrent gross hematuria in 7. All had proteinuria. Three patients presented nephrotic syndrome. Progressive renal failure occured in 10 of 11 male(11 - 39 years) and 1 female (40 years). Six patients were treated with hemodialysis, two of them with transplantation. Sensorineural deafness was observed in 9 patients particularly high frequency sound. Anterior lenticonus were presented in 2. It showed heterogeneitic, 50% transmitted as X-linked dominant(XD) trait. In 7 renal biopsies, the findings by light microscopy mostly revealed focal and segmental sclerosis glomerulonephritis (4/7). The results of immunofluorescenc e (IF) were ne gatt ye in 4. Ultrastructural studies showed variable thickening, thinning of glomerular basement membrane (GBM) in 7 specimens with lamellation and basket-weaving of GBM in 1. Using the iIF technique, the ?3, 4, 5 (Ⅳ) chains were absent within both GBM and EBM of 4 male XD-AS patients. Conclusions AS is not a rare hereditary disease characterized by hematuria, proteinuria and progressive renal failure with sensorineural deafness and ocular lesions. Type Ⅳ collagen within Alpori patients' basement membrane is abnormal and iIF study of type Ⅳ collagen chains distribution is useful to confirm the diagnosis of AS.
8.An analysis on risk factors of radiation-induced oral mucositis in patients with nasopharyngeal carcinoma
Xiaoxia ZHU ; Longhua CHEN ; Yilan CHAO
The Journal of Practical Medicine 2014;(16):2583-2585
Objective To investigate the risk factors of radiation-induced oral mucositis (ROM) and to provide evidence for the prevention of ROM. Methods The severity of ROM was observed and recorded in 56 patients with nasopharyngeal carcinoma. The association of the severity of mucositis with age , sex, clinical stage, concurrent chemoradiotherapy, white blood cell count,BMI index, smoking, alcohol intake, and history of diabetes were assessed by using multivariate logistic regression analysis. Results The severity of ROM was significantly associated with a decrease in leucocyte count (P<0.05), and it was not markedly correlated with the other eight factors (P>0.05). Conclusions Leukopenia was one of the risk factors for the development of ROM. In clinical pratice,leukopenia should be corrected in patients with bone marrow depression due to radiotherapy in a timely manner.
9.The values of the combined detection of serum human epididymis protein E4, CA125 and CA199 in diagnosis of endometrial cancer
Zhi ZHANG ; Hongxia CHEN ; Xiaoxia XU
The Journal of Practical Medicine 2016;32(7):1108-1111
Objective To explore the values of combined detection of serumhuman epididymis protein E4 , CA125 and CA199 in diagnosis of endometrial cancer. Methods 118 patients with endometrial cancer were chosen as group A, 82 patients with benign uterine disease were assigned to group B. Serum levels of HE4, CA125 and CA199 were detected and the positive rates were compared between the two groups. Results Serum levels of HE4, CA125, and CA199, the positive rate were significantly higher in group A than in group B (P <0.05). HE4 positive rate was highest in group A, and group B had no HE4-positive patients. The sensitivity and accuracy of HE4 + CA125 + CA199 were the highest, which was 94.9% and 92.5%. Levels of HE4, CA125 and CA199 and positive rate showed a rising trend as FIGO stage increased (P < 0.05), and HE4 positive rate was significantly higher than those of CA125 and CA199 (P < 0.05). Conclusions HE4 can be used to identify benign and malignant diseases in the uterus , and has a higher diagnostic value of endometrial cancer as compared with CA125 and CA199. Combined detection of HE4, CA125 and CA199 can improve the positive rate and diagnosis accuracy in endometrial cancer.
10.The Quantity Administration Applied to the Physiological Experiment
Lin LI ; Xiaoxia KONG ; Baolang CHEN
Chinese Journal of Medical Education Research 2003;0(04):-
To compare the effect of quantity administration and non-quantity administration on the physiologicalexperiment, the indexes including the experiment success rate, the experiment report score, the experiment operationresult, the experiment theory score and the safety and hygiene assessment mark were observed. The results show that thequantity administration plays a unique part in improving the quality of experiment instruction, training students' innova-tive consciousness and practical ability, reforming the ways of experiment examination and reinforce the managementof safety and environment in laboratory.[