1.Evaluation of plasma matrix metalloproteinase-9 and Interleukin-6 combined with cervical length in the prediction of premature delivery
Journal of Chinese Physician 2012;14(4):477-479,482
ObjectiveTo investigate predictive value of matrix metalloproteinase-9 (MMP-9) and Interleukin-6 (IL-6) combined with cervical length in premature delivery.MethodsPlasma samples of 62 pregnant women were detected in this study.Samples were divided into three groups based on pregnancy outcomes.MMP-9 and IL-6 values were determined by ELISA.Cervical length was measured by transvagihal sonography.ResultsThe level of MMP-9 of the pregnant women in the premature delivery group was significantly higher than that of continuous pregnant group and that of normal pregnant women [(47.24 ±6.41) ng/ml,(523.24 ± 62.35) pg/ml vs (20.39 ±7.23 )ng/ml,(219.29 ± 80.23)pg/ml,(32.18 ±5.16)ng/ml,(406.18 ±71.52) pg/ml,P <0.01].The level of MMP-9 and IL-6 of the pregnant women in the continuous pregnant group was significantly higher than that of normal pregnant women [(32.18 ±5.16)ng/ml,(406.18 ±71.52) pg/ml vs (20.39 ±7.32) ng/ml,(219.29 ± 80.23) pg/ml,P <0.01].Cervical length of the pregnant women in the premature delivery group was significantly shorter than that of normal pregnant women and that of continuous pregnant group [( 15.62 ± 2.31 )mm vs ( 31.05 ± 1.48 )mm,(26.14 ±3.12)mm,P <0.01].ConclusionsDetection of level of MMP-9 and IL-6 combined with measurement of cervical length can be used as predicting index of premature delivery.
2.Effect of Health Education and Psychological Nursing Intervention on the Patients with Postpartum Depression
Hong TAN ; Xiaoyun HU ; Xiaoqun NIU
Journal of Kunming Medical University 2016;37(6):147-150
Objective To explore the clinical effect of health education and psychological nursing intervention on the prognosis of patients with postpartum depression. Methods Ninety cases of postpartum depression in our hospital from March 2012 to March 2014, were randomly divided into the control group and the observation group, 45 cases in each group. The patients in the control group were given routine nursing, the patients in the observation group received health education and psychological intervention on the basis of the control group. The anxiety and depression scores change, medication adherence and quality of life in the two groups were observed and compared. Results The scores of SDS and SAS in the observation group were significantly lower than those in the control group (P<0.05) . The medication adherence and quality of life score 3 months and 6 months after discharge in the observation group were significantly higher than those of control group (P<0.05) . Conclusion Health education and psychological intervention has positive effect on the prognosis of postpartum depression patients, and can effectively improve the patient's medication compliance and quality of life, it's one of the effective measures for the prevention and treatment of postpartum depression.