1.To Evaluate Action and Position of Eight-Principle in Science of Syndrome Differentiation in TCM by Reviewing Evolution of Syndrome Differentiation of Eight-Principle
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(03):-
By reviewing the evolution of syndrome differentiation of eight-principle, it is analyzed that a methodology of logical thinking in syndrome differentiation is the main action of eight-principle in the Science of Syndrome Differentiation. This methodology can standardize and guide other ways of syndrome differentiations. So the eight-principle is of the first position in the Science of Syndrome Differentiation and is a general program for all kinds of syndrome differentiation methodologies.
2.Study thought on diagnosis of TCM syndrome in animal model of modern medicine disease
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(10):-
To define the diagnostic thought on TCM syndrome in animal model of modern medicine disease.To diagnose "apparent syndrome" outside and "hidden syndrome" inside of TCM syndrome differentiation existed possibly in the model animal by multi-aspectual indexes such as observing the appearance of modeled animal,examining the laboratory indexes and morphology,disproving by prescription and medicine etc.It is an effective method of diagnosing TCM syndrome in animal model of modern medicine disease that using multi-aspect and multi-index diagnostic standard.
3.EFFECT OF FGF-10 ON THE SECRETION OF GM-CSF BY NORMAL ADULT HUMAN KERATINOCYTES IN CULTURE
Xiaobing FU ; Xiaoqing SUN ; Wei CHEN
Medical Journal of Chinese People's Liberation Army 2001;0(10):-
To investigate the effect of FGF-10 on the secretion of GM-CSF by adult keratinocytes in vitro and to understand the mechanisms involved in the stimulation of granulation tissue formation by FGF-10 during wound healing. Concentrations of FGF-10 used were 4, 16, 125 and 500 ng/ml. Cells were seeded in the amount of 2 500 cells/cm 2 or 5 000 cells/cm 2 in dishes in serum-free medium, and supernatants were collected at 24, 48 and 72 hours after culture. The amounts of GM-CSF in cell culture supernatants were determined using GM-CSF ELISA kits, and cell numbers were counted by haemocytometer. For cells seeded in low density (2 500 cells/cm 2), GM-CSF was not detected at 24 hours. At 48 hours, both in absolute concentrations and on a per-cell basis, the amounts of GM-CSF secreted in cultures with 125 and 500ng/ml FGF-10 were significantly higher than that in negative control (P0.05). At 48 hours, the keratinocytes in the middle area were confluent, and a number of cornified cells were observed, while the productions of GM-CSF in FGF-10 cultures were not higher than that in negative control. There was a clear negative correlation between the secretion production of the growth factor and the total cell number in each dish with a correlated coeffecient of 0.881 (P
4.GENE EXPRESSION OF p38 MITOGEN-ACTIVATED PROTEIN KINASE AND ITS MAPKKs IN HYPERTROPHIC SCARS
Wei CHEN ; Xiaobing FU ; Xiaoqing SUN
Medical Journal of Chinese People's Liberation Army 2001;0(07):-
To explore the change in gene expressions of p38 mitogen-activated protein kinase (p38MAPK) and its upstream signal-regulated molecule (mkk3 and mkk6) in normal skin versus hypertrophic scars underlying its potentially biological significance. Total RNAs were isolated from 8 specimens of hypertrophic scars and 8 specimens of normal skin, then they were purified to mRNAs, and the gene expression of mkk3, mkk6 and p38MAPK was examined with reverse transcription-polymerase chain reaction (RT-PCR). The results showed that the intensities of gene expression of mkk6 and p38MAPK were weak in normal skins, while the expression of these 2 genes was significantly elevated in hypertrophic scars compared with normal skins (P0.05). In hypertrophic scar, the elevation of mkk6 and p38MAPK gene expression, which plays pilot roles in cell proliferation, may be one of the mechanisms controlling the formation of hypertrophic scars.
5.Study on the correlation between chronic sinusitis with nasal septum deviation.
Xiaoqing JI ; Hongjuan FU ; Aiqin SONG
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2015;29(12):1103-1104
OBJECTIVE:
Study on the correlation between chronic sinusitis with nasal septum deviation.
METHOD:
Randomly selected 722 patients with coronal sinuses CT, statistics the number of cases of nasal septum deviation, cases of nasal septum deviation with chronic sinusitis, the wide and narrow side cases of nasal septum deviation complicated with sinusitis. The number of sinusitis without deviation, and paired test.
RESULT:
The incidence of sinusitis between deviation of nasal septum and non deviation were 54. 13% and 44. 66%, the difference between two groups was statistically significant (P<. 05), the incidence of sinusitis with nasal septum deviation of wide and narrow side were 31. 65% and 32. 12%, no significant difference between the two groups (P>0. 01). The incidence of sinusitis high deviation and non high deviation were 59. 54% and 46. 97%, the difference between the two groups was statistically significant (P<0. 05). The number of wide side of upper nasal septum deviation with sinusitis was 54, the narrow side was 66, there is no significant difference between the two groups (P>0. 05).
CONCLUSION
The deviation of nasal septum is associated with the formation of chronic sinusitis, the high deviation is more prone to sinusitis, The incidence of sinusitis and nasal septum deviation on both sides was no different.
Chronic Disease
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Humans
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Incidence
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Nasal Septum
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pathology
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Sinusitis
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physiopathology
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Tomography, X-Ray Computed
6.Research on the application of multimedia technology in the clinical teaching of pediatric Surgery
Yi WANG ; Xiaoqing LI ; Yuexian FU
Chinese Journal of Medical Education Research 2006;0(07):-
Pediatric surgery is the important part of the paediatrics,and the complicated content,limited time and many difficulties are the main problems of pediatric surgery teaching.The bed side teaching is the supplement for the class teaching,which could solve those problems.Multi-media technique is used in bed side teaching of Pediatric surgery,which is convenient for preparing lesson and teaching of teachers and review and summary of students.After the technique is used,the teaching efficiency and the quality are obviously improved.
7.Observation of ankle pump motor in the prevention of deep vein thrombosis after surgical operation
Xiaoqing YI ; Aifeng FU ; Aimin FU ; Huijuan LI ; Qiuxia ZENG
Chinese Journal of Practical Nursing 2013;(16):36-38
Objective To evaluate the influence of ankle pump motor on deep vein thrombosis after surgical operation.Methods 138 cases of patients after surgical operation who were assessed as high risk patients,were randomized into the study group (70 cases)and the control group (68 cases),routine nursing was adopted in the control group,while in the study group,ankle pump motor was adopted in addition.The incidence of deep vein thrombosis was compared between two groups.Results No deep vein thrombosis was found in the study group,while 1 case of thrombosis was detected in the control group,but there was no statistic difference.Conclusions Ankle pump motor was easy and convenient,and can prevent deep vein thrombosis by promoting the reflux of the lower limbs,improving the recovery of patients after operation,and increasing nursing quality as well.
8.Influence of postural intervention to ambulation of patients after video-assisted thoracoscope surgery
Xiaoqing YI ; Aifeng FU ; Aiming FU ; Meng LI ; Liping ZHONG
Modern Clinical Nursing 2013;(5):55-57
Objective To study the influence of postural intervention on ambulation of patients after video-assisted thoracoscope surgery? Methods One hundred and forty eight patients having undergone chest cardiac surgery were randomly divided into the control group(n = 75)and the observation group(n = 74)? The former received routine nursing intervention and the latter postural intervention besides routine nursing? The two groups were compared in terms of the time for ambulation and the ability in ambulation? Result The ambulation in the observation group was earlier than the control group and the ability in ambulation was better compared to the control group(both P < 0?05)? Conclusion The postural intervention after thoracic surgery is effective in pushing patient’s ambulation and improve their ability?
9.Correlation of Smad protein expressions with liver fibrosis in patients with chronic HBV infections
Jianfeng BAO ; Qunwei CHEN ; Jianchun GUO ; Xiaoqing FU ; Junping SHI
Chinese Journal of Clinical Infectious Diseases 2011;04(6):348-351
Objective To evaluate the association of Smad2/3,Smad4 and P-Smad3 protein expressions in tissue with liver fibrosis in patients with chronic HBV infections.Methods Liver biopsy was performed to determine the liver fibrosis grades in 131 cases of chronic HBV infections.Immunohistochemistry and semiquantitative analysis were applied to detect the expression of Smad2/3,Smad4 and P-Smad3 proteins in liver tissues.Results Smad2/3,Smad4 and P-Smad3 were detected mainly in fibrous septum,portal areas,myofibroblasts,sinus and cytoplasm in the liver tissue.The expression of Smad2/3,Smad4 and P-Smad3 was increased with the development of fibrosis ( r =0.81,0.58and 0.68,P =0.000),and a strong positive correlation was observed among three proteins (r =0.75,0.87and 0.84,P =0.000).Conclusion The expression of Smad2/3,Smad4 and P-Smad3 is correlated with liver fibrosis in chronic HBV infection,which suggests that the up-regulation of Smad proteins may be involved in the progression of liver fibrosis.
10.Comparison of the levels of serum prolactin and the concentrations of anti-infective factors of human colostrum in normal labor and cesarean section
Fengming FU ; Jianwei JIANG ; Xiaoqing LUO ; Tao YE
Chinese Journal of Pathophysiology 2001;17(6):563-565
AIM: To compare the difference in serum prolactin levels and the concentrations of anti-infective factors of human colostrums between normal labor and cesarean section. METHODS: The serum prolactin levels were measured at 48 h, 96 h after parturition in 100 cases of normal labor and cesarean using radioimmunoassay. Furthermore, the levels of SIgA, IgG, IgM, C3, C4 were tested in 100 cases at the same time using the technique of immuno-turbidimetry. RESULTS: The serum prolactin levels in normal labor tested at 48 h after parturition were significantly different with that of the cesarean section group. But there was no significant difference in serum prolatin levels 96 h after parturition between the two groups. The levels of SIgA,IgG,IgM,C3 and C4 of the colostrum in the cesarean group were higher significantly than those of the normal group at 48 h after parturition. (P<0.05 or P<0.01). At 96 h after parturition, there was no significant difference in SIgA, IgG, IgM and C3 between the two groups except C4. CONCLUSION: At 48 h after paturition, the serum prolactin levels of normal labor group are higher than that of the cesarean section group. The concentrations of anti-infective factors (SIgA, IgG, IgM, C3 and C4) of human colostrums at 48 h after paturition in cesarean section group are higher than those of normal labor group.