Objective To make sure the nursing measurees of anodynia fiberoptic bronchoscopy examination,and then summarize the nursing experiments. Methods Analyze the concreted nursing measures of 120 patients with anodynia fiberoptic bronchoscopy examination. Results There were no anesthesia poison and complication during the course of examination because of the perfect nursing measures Conclusion Strengthen the psychological nursing of patients,kept the air way unblocked and made sufficient preparation before examination were the keys of obtain successful anodynia fiberoptic bronchoscopy examination.

Objective To investigate the effect of tourniquet modified strapping on venipuncture in tumor patients.Methods 120 tumor patients whose veins were exposed hard in radiotherapy department from October 2016 to March 2017, randomly divided into the control group and the observation group equally.The control group was treated with the traditional single strapping tourniquet to have venipuncture and the observation group with tourniquet modified strapping.Results The venous filling degree, the success rate of first puncture, and the satisfaction of the patients in the observation group were significantly higher than those in the control group (P<0.05).Conclusion The use of tourniquet modified strapping in tumor patients whose veins were exposed hard can significantly improve the venous filling degree, the success rate of puncture, the satisfaction of patients and the quality of nursing service, and thus it is worthy of clinical promotion.

Objective To observe the clinical characteristic and prognostic analysis of severe anti-N-methyl-D-aspartate receptor ( anti-NMDAR) encephalitis.Methods The clinical data of 9 patients with severe anti-NMDAR encephalitis were retrospective analyzed.Results Nine patients ( two male and seven females ) were taken care at ICU.They were 27.7 years old at average.The median course was 22.4 d and median length of stay in ICU was 50. 9 d.The mainly clinical characteristics were fever(7 cases), psychiatric behavioral symptoms(9 cases), seizures(9 cases) , decreased consciousness ( 8 cases ) , abnormal movement ( 7 cases ) , automatic instability ( 9 cases ) and hypoventilation(6 cases) .Three cases had ovarian teratoma.Anti-NMDAR antibodies in CSF of all patients were testing positive, while in serum were 6 cases.CSF-IgA in 7 cases were increased.The brain MRI indicated abnormal signals in temporal lobe, hippocampus in 3 patients.The EEG showed slowing wave abnormal in 5 patients.All patients were treated with combined first-line immunomodulatory therapies with steroids, intravenous immunoglobulin, or plasma exchange. Five patients were fullly recoveried, 4 patients were improved with residual symptoms. Conclusions Severe anti-NMDAR encephalitis may present progress quickly mental behavior change, epilepsy, and disturbance of consciousness, movement disorders, autonomic nerve dysfunction.Which accompanied with tumor is rare.Most patients with active immunotherapy can get good prognosis.

ObjectiveTo investigate the influence of r egional wall motion abnormality(RWMA) on cardiac anatomic structure with coronary artery disease (CAD) and to recognize serious degree of the disease by echocardiography. MethodsA total of 125 cases was observed. There were 63 patients in CAD group (41 cases with general CAD,7 cases with acute myocardial infarction and 15 cases with old myocardial infarction). All the patients had undergone respectively CABG,PTCA and stent,coronary angiography or radionuclide scan for confirmation. There were 62 cases in normal control group. Using 2D echocardiography,stand short and long axis images of left ventricle(LV) were chosen. Displayed RWMA to compose the centripetal disharmonized motion with whole-wall of LV,and the discentripetal contradiction motion. M mode for continuous scan was to detect the typical characterisitic of RWMA. ResultsSingle-occurring RWMA from 43 cases ( 68.2 %) in 63 cases with CAD was displayed, while multiple-occurring RWMA from another 20 cases ( 31.8 %) was displayed(P

Objective To observe the effects of Wenxinkeli combination use with buspirone on the treatment of cardiac neurosis with ST-T changes.Methods Ninety patients with cardiac neuropathy were randomly divided into placebo group, Wenxin Granule group and combination use group (Wenxinkeli combination use with buspirone),30 cases in each group.The scores of HAMA-14 and HAMD-24 of the three groups were observed at the end of 4 and 8 weeks after treatment when the score of SF-36 and the improvement of ST-T of combination use group were evaluated followed 12 weeks treatment.Results After 4 weeks of treatment, the two scale scores of combination use group and the Wenxinkeli group, including HAMD-24 and HAMA-14, were significantly lower than the placebo group (P<0.05).In comparison with placebo group, the scores of HAMD-24 and the HAMA-14 were significantly lower after 8 weeks treatment.After 12 months of follow-up treatment, the SF-36 scores of combination use group were significantly higher than the other two groups'(P<0.05).Meanwhile, our results showed that the ST-T changes of the combination use group was significantly improved than the other two groups'(P<0.05).Conclusion The treatment of Wenxinkeli combination use with buspirone can significantly decrease anxiety and improve depression in patients with cardiac neurosis, moreover, long-term combination use treatment can distinctly improve patients' quality of life and relieve their physical symptoms of ST-T changes.

Objective To study the changes in echocardiography in normotensive patients with type2 diabetes mellitus (T2DM) in order to establish early diagnosis and give preventive measures for diabetic cardiomyopathy (DCM). Methods Microvasculopathy was diagnosed in T2DM patients when microalbuminuria exceeded 15ml/min. Fifty-four T2DM patients were divided into two groups: group A (patients without microvasculopathy, n=32 ), group B (patients with microvasculopathy, n=22). All of T2DM were submitted to echocardiography and the results were compared with healthy people of matched sex and age (group C, n=20). Results There were no differences in systolic function parameters among the groups. Left ventricular mass index (LVMI) was higher in two groups of diabetics compared with group C. Diastolic dysfunction of various degrees was found in the two groups of diabetics, regardless of the presence of microvasculopathy, with a manifestation of a decrease of blood flow velocity in early diastolic phase and increase in late diastolic phase (P

Objective To explore the value of craniocerebral CT angiography(CTA) to evaluate the prognosis in patients with acute cerebral infarction(ACI).Methods Craniocerebral CTA were performed in 70 patients with ACI at ≤6 h after onset.National Institutes of Health Stroke Scale(NIHSS) score and modeled Rank Scale(mRS) score were investigated at admission,discharge.Results There were 38 patients with visible occlusion on CTA and 32 patients with normal CTA.The patients with vessel occlusion on CTA had significantly worse discharge scores of NIHSS(P0.05).But for patients with vessel occlusion,the ratio of good prognosis in patients received thrombolytic treatment was higher than that of excluded thrombolysis(58.8% vs 31.8%;P

ObjectiveTo explore the effects and significance of acetazolamide on the expression of aquaporin-4(AQP4) of gastric mucosal in rats with endotoxemia. Methods30 SD rats were randomly divided into 3 groups: Sham operated control group( Control group) ,endotoxemia group( EDT group) and acetazolamide group( ATL group).The immunohistochemistry was used to assess the expression of the AQP4 in the gastric mucosal tissues. The serum tumor necrosis factor-α(TNF-α) and interleukin-1 β(IL-1β) levels in each group were measured by radioimmunoassay. ResultsThe expression of AQP4 and the levels of serum TNF-αt and IL-1 ββ in EDT group were higher than those in control group( P ＜ 0.01 ). After the ALT treatment, the expression of AQP4 and the levels of serum TNF-α and IL1 β in ALT group were lower than those in EDT group( all P ＜0.01 ) and the expression of AQP4 in the gastric mucosal tissues in ALT group was also lower than those in EDT group( P ＜0.01 ). ConclusionThe raising of AQP4 expression and increasing of serum TNF-α, IL-1β take part in the progress of gastric mucosal injury in rats with endotoxemia. ALT could protect the gastric mucosal tissues by lowering the AQP4 expression and reducing the levels of serum TNF-α and IL-l β.

Objective To increase the normative follow-up rate of organ transplant recipients,and to improve their long-term survival rate of patients and their life quality.Methods Establish a normative follow-up management system of organ transplantation,improve the follow-up rules and link management,strengthen the whole-course health education and provide comfort and warm service for patients.Results ( 1 ) The results of patients/renal survival rates at different times indicated that the 1 year,3 year and 5 year patients/renal survival rates in the normative follow-up group were significantly higher than that in the random follow-up group,P ＜ 0.05.( 2 ) The 1-year follow-up results for the outpatients indicated that no difference in one-year follow-up rate were observed in both groups (98.4％ vs.97.5 ％,P =0.128).And the 3 year and 5 year follow-up rates in the normative follow-up group were statistically significantly higher than that in the random follow-up group (90.1％ vs.85.5％,88.3％ vs.55.3％,P ＜ 0.001 ).Conclusion Establishment of the sound and normative follow-up management system of organ transplantation was helpful to improve the long-term survival rates of patients and their life quality.