An extranodal lymphoma, primary central nervous system lymphoma(PCNSL) has rarely been reported. PCNSL is commonly classified as a primary diffuse large B-cell lymphoma with pathology. The WHO classification of haematopoitic and lymphoid tissues(4th Edition, 2008) has listed primary diffuse large B-cell lymphoma as a independent disease entity. Current clinical diagnosis of PCNSL is this article in reviewed.

Acupuncture and rehabilitation therapies were used to treat 40 cases of shoulder-hand syndrome, the results show that integration of acupuncture and rehabilitation can increase therapeutic effects and shorten treatment courses to accelerate recovery.

Biliary cystic tumors (BCTs) are rare cystic tumors and are accounted for less than 5％ of liver cysts.BCTs are very common in middle-aged and elderly women,and depend on diagnosis of imaging including papillary projection or multilocular cystic liver mass.BCTs are frequently misdiagnosed due to the absence of specific diagnostic indicators,which should differentiate from diagnosis of hepatic cystic.Complete surgical resection is the first choice for BCTs with a good out-come,in addition to low recurrence.Once recurrence was identified in follow-up,BCTs can be treated by reoperation with a good outcome.

Objective To investigate the protective effects of Lycopene (LP) on hepatic oxidative stress injury in type 2 diabetic rats.Methods The diabetic rat models were setup by intraperitoneal injecting STZ (60 mg/kg). 60 models were selected and randomly divided into three groups: diabetes model control group, LP 10 and 20 mg/kg treated groups, with 20 experimental animals in each group. While, selected another 20 normal same-aged rats as normal control group. The drug was given by intragastric administration for 4 weeks, once a day. Before the drug was given and after 2, 4 weeks, the level of blood sugar was determined. Four weeks later, the body weight and hepatic index were detected; the activity of ALT, AST, ALP and the level of T-AOC in serum were determined; the activity of SOD, GSH-Px, CAT and the content of MDA in hepatic tissue were determined; and the hepatic tissue histopathological changes was observed by HE staining.Results Compared with the diabetes model group, the activity of ALT in serum of LP 10, 20 mg/kg treated groups was significantly decreased (714.8±291.5 U/L, 862.7±348.1 U/Lvs. 1 007.6±375.7 U/L); AST was significantly decreased (75.2±18.6 U/L, 87.6±20.3 U/L vs. 99.3±21.5 U/L); and the content of MDA in hepatic tissue was significantly decreased (5.56±1.02 U/L, 5.83±0.98 U/L vs. 6.37±1.18 U/L); the blood sugar level of LP  20 mg/kg treated group was significantly decreased(16.6±1.1 mmol/L vs. 17.9±1.2 mmol/L), the body weight was significantly increased(281.5±24.8 g vs. 252.3±23.5g) and the hepatic index was significantly decreased (26.2±5.3 ‰vs. 30.4±5.8‰), the activity of ALP in serum was significantly decreased (135.2±30.8 U/L vs. 167.4±32.5 U/L) and the level of T-AOC was significantly increased (10.8±2.8 U/L vs. 8.7±2.4 U/L), the activity of SOD in hepatic tissue was significantly increased(10.8±2.3 U/mgvs. 9.1±2.3 U/mg), GSH-Px was significantly increased (16.1±3.4 U/mgvs. 14.3±3.5 U/mg), CAT was significantly increased (3.16± 1.08 U/mgvs. 2.63±0.90 U/mg).ConclusionLP had dose-dependent protective effect for hepatic oxidative stress injury in type 2 diabetic rats.

Objective To explore the efficacy and safety of multimodality analgesia for patients undergoing radical resection of colon cancer.Methods Seventy patients aged 46-75 years old,undergoing the radical resection of colon cancer were divided randomly into two groups:the trial group (parecoxib preemptive analgesia and ropivacaine local analgesia combined with sufentanil patient-controlled intravenous analgesia) and the control group (sufentanil patient-controlled intravenous analgesia only),each group of 35 patients.The visual analogue scale (VAS) and the usage amount of sufentanil were recorded at 12,24,48 h after operation.The number of unsatisfied demand and the number of successfully delivered doses,sufentanil consumption at 12 h and 24 h after operation,the patients' global evaluation of the postoperative analgesia and adverse effects related to analgesia were recorded and compared between the two groups.Results The VAS scores at 12,24 h after operation in trial group were lower than those in control group [(3.1 ± 1.0) scores vs.(4.0 ± 1.3) scores,(2.8 ± 1.4) scores vs.(3.7 ± 1.2) scores].The degree of satisfaction in trial group was higher than that in control group(P ＜ 0.05).The demand and the number of successfully delivered doses and the usage amount of sufentanil in trail group were significantly lower than those in control group (P ＜ 0.05).The incidence of respiratory depression,nausea and vomitting in trial group were significantly lower than those in control group[0 vs.5.7％(2/35),2.9％(1/35) vs.11.4％ (4/35)] (P ＜ 0.05).Conclusion Multimodality analgesia may have the good analgesic effect in the patients undergoing radical resection of colon cancer,and with fewer adverse events.

Objective To understand the distribution characteristics of HIV infection status among the outpatients in this hospi-tal to provide the beneficial supplement for local large-scale survey and the basis especially for the hospital infection control.Meth-ods The HIV screening situation on the outpatients of our hospital from 2007 to 2012 was retrospectively analyzed.Results Dur-ing these 6 years,108 999 specimens were detected,88 cases were positive in the preliminary screening and 81 cases were confirmed positive.The positive rate of anti-HIV antibody was 0.074%.In addition to voluntary counseling and testing,the specimens submit-ted by the outpatient anorectal department and the inpatient hematology department had the higher positive detection rate,which was 1.16% and 0.84% respectively.Conclusion The HIV infection rate in non-infectious disease specialized hospitals shows the increasing trend.The key departments must increase the intensity of the medical staff training,pay attention to early diagnosis of HIV/AIDS,prevent the hospital infection and reduce the risk occurred after the occupation exposure.

Hepatocellular carcinoma (HCC) is the most common malignant cancer in China. The size of HCC can be categorized into 4 grades: (1) micro-HCC, the diameter of the HCC is ≤2 cm; (2) small HCC, the diameter of the HCC is between 2 and 5 cm; (3) large HCC, the diameter of the HCC is between 5 and 10 cm; (4) giant HCC, the diameter of the HCC is > 10 era. The new classification helps to choose the appropriate methods and to analyze the curative effect for various kinds of HCC respectively. The resection of large and giant HCC is safe and feasible. During the past 20 years, we have modified and innovated some techniques of HCC surgery, including hepatectomy without dissecting the hepatic hilus, increasing the safety time limit of portal pedicle occlusion from 15-20 minutes to 20-60 minutes, in situ bepatectomy with occlusion of hepatoduodenal ligament and infrahepatic vena cava, and double hanging maneuver techniques. The techniques mentioned above improved the bleeding control of hepatectomy, and enhanced the long-term survival rate of HCC patients.

OBJECTIVE: To study the effects of Folium Crataegi water extract on contractility of isolated gastric and intestinal smooth muscle strips in rats. METHODS: The effects of Folium Crataegi water extract on the contractility of isolated rat gastric and intestinal smooth muscle strips in the presence of normal Krebs’ solution, acetylcholine or atropine were investigated. RESULTS:Folium Crataegi water extract (5～20 mg?mL-1)significantly enhanced the contractility of rat gastric and intestinal smooth muscle strips in a dose-dependent manner, and Folium Crataegi water extract (20 mg?mL-1) could enhance the intensive contraction induced by acetylcholine and antagonize the relaxation of intestinal smooth muscle induced by atropine. CONCLUSION:Folium Crataegi water extract has remarkable stimulation on the contractility of isolated rat gastric and intestinal smooth muscle strips.

This paper clarifies the internal connection of hospital management and medical ethics,and points out that hospital management should be based on medical ethics management,for their combination could be the future trend of modern hospital management.It is of particular importance to clarify and further strengthen the significance of medical ethics management during hospital management,thus reasonably combine hospital management and medical ethics management,in order to promote a healthy development of hospitals.

Objective: To observe the position change of the upper mol ar s and incisors in cases with Angle class I malocclusion and crowding treated by extraction of four first premolars. Methods: 20 patients with An gle class I malocclusion and crowding aged 14-16 years old, 8 male and 12 femal e, were treated by extraction of the four first premolars, and Edgewise applianc e. Two X-ray cephalometry films were taken for every patient before and after t reatment, cephalometry measurements were obtained and the position of the upper molars and incisors were analyzed. Results:The treatment was co mpleted in 18 month on average in all patients. After treatment, the crown of th e upper first molars showed mesial displacement of 3.15 mm on average, the crown of the upper incisors distal displacement of 2.55 mm, the crown of the lowe r first molars mesial displacement of 4.3 mm, the crown of the lower incisors d istal displacement of 1.77 mm. Conclusion: With of dental anchor age, the position changes of the upper molars and incisors in the cases with Ang le class I malocclusion and crowding after extraction treatment may be achived.I n relation to RL line,the mesial displacement of molars are larger than the dist ally displacement of incisors.