1.Different viewpoints on opening peacekeeping medical support to local people
Journal of Medical Postgraduates 2003;0(12):-
During the period of December 2004 to July 2005,we were deployed to the Untied Nations mission in Liberia(UNMIL) of the West Africa.At that time,some civilian officers of UNMIL advocated an intention that is called "army-civilian joint together to establish a new complex peacekeeping hospital" and unrealistically expected to implement "a visualized show" in Chinese level Ⅱ hospital.According to the principle of the Memorandum Understanding and the medical standard operating procedure of United Nations,we kept avoiding the contravention of the military medical support rules of UNMIL effectively with the strategy of prevention,treatment,and education for the local civilians,such as distributing medicine for epidemic prevention to the multinational troops,assisting the international volunteer hospital,performing "Life and limb" surgery on civilians,and training the local medical personnel.We settled the awkward question of what is the best to help the local people during the peacekeeping mission.It is necessary to seriously study this great dilemma and summarize our practice in offering medical support to the host country people during the peacekeeping mission,which will promote the development of Chinese PLA peacekeeping operation.
2.United Nations' telemedicine and Chinese level Ⅱ hospital:medical support for the peacekeeping operation
Journal of Medical Postgraduates 2003;0(05):-
To complete the mission of medical support of peacekeeping operation doctor and nurse were trained in the Chinese level Ⅱ hospital to use telemedicine and the technical sustainment of communication equipments which enhances the actual combat capability of our medical personnel.
3.Practice in the rotation of the Chinese peacekeeping medical contingent
Journal of Medical Postgraduates 2003;0(04):-
Objective: To summarize the experience of the Chinese peacekeeping medical contingent in rotation after successful accomplishment of its peacekeeping mission.Methods: From December 2004 to July 2005,the Second Chinese Peacekeeping Medical Contingent was carrying out its peacekeeping medical support mission in West Africa.It successfully accomplished its mission entrusted by the United Nations,its long-distance intercontinental deployment and evacuation from the mission area,as well as its rotation by two-batch-mode handovers in an organizational system.Results: Smooth rotation ensured the fulfillment of the medical support mission,harmonious relationship with various units,close cooperation with related sections,joint action with multination forces and uninterrupted work performance.It tested the contingent's combat readiness and medical support ability.Conclusion: The rotation of the Untied Nations peacekeeping medical support forces provided an all-round training for the Chinese medical contingent and helped it adapt to the future warfare in the international setting,which is of great practical significance for strengthening military preparedness of the army.
4.Expression and clinical significance of cyclooxygenase-2 in multiple myeloma
Ying HU ; Shilun CHEN ; Xiaonan HUANG ; Na AN
Journal of Leukemia & Lymphoma 2008;17(5):337-339
Objective To investigate the expression of COX-2 in multiple myeloma(MM)and the relationship between myeloma cells proliferation and apoptosis.To provide a new prognosis factor and therapeutic target.Methods COX-2 from the 22 newly diagnosed MM,14 relapsed MM and PCNA,HSP70 of the newly diagnosed patients were detected by immunohistochemistry method.Results All the newly diagnosed MM exhibited positive COX-2 immunoreactivity.50% had strong COX-2 and 50% showed weak COX-2.Relapsed MM exhibited strong COX-2.COX-2 was related with serum β2 microglobulin,marrow plasma cells,hemoglobin,PCNA,HSP70(P=0.019,0.003,0.048,0.006,0.034).Conclusion COX-2 was overexpressed in MM.Prognosis of patients with strong COX-2 is poorer than those with weak COX-2.COX-2 may promote the proliferation and inhibit the apoptosis of myeloma cells.
5.The sleeping status of Chinese Peace-Keeping Force in Liberia
Jinsong LI ; Yurong WANG ; Xiaonan HU
Journal of Medical Postgraduates 2003;0(03):-
Objective: To evaluate the sleeping status of Chinese Peace-Keeping Force in Liberia,and to ensure soldiers' somatic and mental health. Methods: Written questionnaires about the sleeping status were collected twice from Chinese military staff at two independent intervals. Results:The sleeping status of the soldiers was worse in Liberia than at home,but it became better at later stage when soldiers adapted to the environment and the job,when the weather became less hot,and appropriate medical treatment was used. Conclusion: Improving occupancy condition,adjusting night duty to ensure adequate sleeping time for the night duty soldiers,strengthening the sleeping hygiene education and proper medical treatment were important for the severe insomnia soldiers.
6.Progress of the relationship between cyclooxygenase-2 and breast cancer
Xinmiao YANG ; Xiaonan HONG ; Xichun HU
China Oncology 2000;0(06):-
Recent researches indicated that cyclooxygena se -2 (COX-2) expression was related not only to development of breast cancer but also to clinicopathological parameters and prognosis of advanced breast cancer. The preclinical and clinical studies on the use of selective COX-2 inhibitors f or the prevention and treatment of breast cancer have become the focus of invest igation.
7.Results of treatment of multimodality therapy following bladder-preserving surgery for muscle-invasive bladder cancer
Xiaonan SUN ; Jianbin HU ; Qichu YANG
Chinese Journal of Radiation Oncology 1993;0(03):-
Objective To evaluate the local control effect of radiotherapy and intravesical chemotherapy following bladder preserving surgery for musculoinvasive bladder cancer. Methods Twenty three patients with muscle invasive bladder cancer were treated by bladder preserving surgery followed by external radiation ( mean dose 52.5 Gy) combined with intravesical mitomycin infusion after bladder preserving operation (study group).For comparison, 29 similar patients received the same treatment without radiation served as control (control group).Results All patients in the study group completed their designed treatment,except two patients whose protocol was interrupted for 3 days and one week due to acute cystitis. The mean follow up duration was 41.6 months. The 3 year local recurrence rates were 18.8% in the study group and 44.8% in the control group(P=0.026).The 3 year distant metastasis rates were 18.2% and 24.1% (P=0.437),and the 3 year overall survival rates were 81.8% and 86.2% (P=0.670),respectively. Conclusion It is demonstrated that adjuvant radiotherapy and intravesical infusion chemotherapy following organ preserving surgical procedure are encouraging by giving favorable local control for musculoinvasive bladder cancer.
8.Progress of the mechanism study of partial left ventriculectomy
Bo WANG ; Xiaonan HU ; Hua JING
Journal of Medical Postgraduates 2003;0(05):-
Partial left ventriculectomy(PLV),also named as left ventricular volume reduction or the Batista procedure,is gradually used as a new alternative method to treat end-stage heart disease.This article summarizes the progress of the mechanism of partial left ventriculectomy with rapid left ventricle reshaping and hemodynamics change and patho-physiological effect etc.
9.Serum vascular endothelial growth factor levels in patients with non-small cell lung cancer and its relations to the micrometastasis in peripheral blood.
Yang, JIN ; Xianzhi, XIONG ; Yuan, SU ; Jianwu, HU ; Xiaonan, TAO
Journal of Huazhong University of Science and Technology (Medical Sciences) 2009;29(4):462-5
To examine the relationship between the levels of the serum vascular endothelial growth factor (VEGF) and the micrometastasis of peripheral blood in patients with non-small cell lung cancer (NSCLC), 108 NSCLC patients, including 40 patients with benign lung diseases and 30 healthy controls, were investigated. The serum VEGF levels were detected by ELISA and CK19 mRNA in peripheral blood by reverse transcriptase-polymerase chain reaction (RT-PCR). In NSCLC group, the serum VEGF levels and the positive rate of CK19 mRNA in peripheral blood were 479.8+/-268.5 pg/mL and 66.7%, which were significantly higher than those of the other two groups respectively (P<0.01), and both of them were increased significantly with the progression of clinical stage of the tumors (P<0.01). Serum VEGF levels as well as the positive rate of CK19 mRNA in different pathological types of lung cancer had no significant differences (P>0.05). Serum VEGF levels in the patients positive for CK19 mRNA was 561.7+/-325.6 pg/mL. It is significantly higher than that in the negative patients (P<0.01). There existed a significant correlation between serum VEGF levels and expression of CK19 mRNA in peripheral blood in NSCLC patients (P<0.001). The detection of serum VEGF levels and CK19 mRNA in peripheral blood is helpful in judging the condition and the prognosis of NSCLC patients, and serum VEGF levels and CK19 mRNA are independent of the pathological types of lung cancer. The micrometastasis in peripheral blood of NSCLC patients is significantly associated with serum VEGF levels.
10.Heart valve replacement for giant left ventricle: Clinical analysis of 138 cases
Liguo LUO ; Hua JING ; Xiaonan HU ; Demin LI ; Zhongdong LI
Journal of Medical Postgraduates 2003;0(04):-
Objective: Giant left ventricle is one of the important dangerous factors impacting the results of valve replacement operation.In order to improve the efficiency of operation,we summarized our experience in valve replacement surgery for patients with giant left ventricle(LVEDD ≥ 7.0 cm).Methods: We retrospectively analyzed the clinical data of 138 cases of giant left ventricle treated by valve replacement operation in our hospital from June 1996 to April 2008.The preoperative left ventricular end diastolic dimension(LVEDD),left ventricle end systolic dimension(LVESD),left ventricular ejection fraction(LVEF) and left ventricular fractional shortening(LVFS) were 7.38-10.51 cm(mean 7.98?0.39),5.20-7.93(mean 5.88 ? 1.03),0.21-0.66(mean 0.43 ? 0.11) and 0.10-0.45(mean 0.25 ? 0.07),respectively.Eighty-nine of the patients had the heart function(NYHA) of class Ⅲ,and the other 49 class Ⅳ.Mitral valve replacement(MVR) was performed for 57 cases,aortic valve replacement(AVR) for 26,double valves replacement(DVR) for 40,and Bentall operation for the other 15.Meanwhile,78 of them underwent tricuspid valve plasty(TVP),and another 17(LVEDD ≥8.5 cm and LVEF ≤ 25%) partial left ventriculectomy(PLV).Results: The early postoperative mortality rate was 5.8%,mainly due to postoperative multiple organ failure,severe low cardiac output syndrome and ventricular fibrillation.Compared with the preoperative data,postoperative echocardiography showed that LVEDD and LVESD were decreased slowly at 2 weeks,and LVEF and LVFS significantly improved at 6 months.In the 17 patients who underwent PLV,LVEDD and LVESD were significantly reduced at 2 weeks,and LVEF and LVFS markedly improved.Conclusion:The key to the efficiency of valve replacement for giant left ventricle was proper choice of the blood containing stop-beating fluid during the operation,preserving the posterior valve of the mitral valve and the structure beneath it,shortening aortic cross-clamping time as much as possible,and perioperative prevention and management of arrhythmia.The short-term effect of valve replacement with simultaneous PLV is satisfactory,while its long-term effect is yet to be further investigated.