Objective To scrutinize the CT features of pulmonary actinomycosis and analysize the causes of misdiagnosis.Methods CT images of eleven patients with pulmonary actinomycosis proved by pathology were retrospectively reviewed.Among them,6 were scanned with additional enhanced CT scan.Results Among the 11 patients,the lesions located in the inferior lobe in 7 patients,and in the superior lobe in 4 patients.The lesions affected two or more pulmonary segments in 9 patients,6 of them involving two lobes.Irregular mass or nodules with necrotic low-attenuation areas were the main signs in all patients,and segmental consolidations were found in 6 patients.Peripherally progressive enhancement was found in all patients with contrast enhanced CT scan.Vicinity pleural thickening was found in 11 patients,while extrapleural fat deposition was found in 6 patients.One case showed erosion of the chest wall and rib.Conclusion Pulmonary actinomycosis is a chronic suppurative granulomatous inflammation,which is often misdiagnosed with neoplasm or other lung disease because of its mass-like performance.The peripherally progressive enhancement on CT has a certain diagnostic value for P\pulmonary actinomycosis.

Objective To evaluate prognostic effects and complications of interventional embolization at different time points on patients with ruptured intracranial aneurysms of Hunt -Hess Ⅳ-Ⅴlevels.Methods Through a retrospective analysis from 2008.1 to 2012.12, we collected 162 from 200 patients who underwent interventional embolization due to ruptured intracranial aneurysms according to the criteria.Patients with serious neurological disorders , coma, and end-stage diseases were excluded.Brain CT scan was performed to identify the spontaneous subarachnoid hemorrhage of the patients , followed by CTA or digital subtraction angiography ( DSA) to ensure the accurate diagnosis of intracranial aneurysms.All of the patients at Hunt-HessⅣ-Ⅴlevels were treated with interventional embolization , and were divided into two study groups:early stage therapy group of 79 patients ( embolization at the time <72 hours after the onset) and late stage therapy group of 83 patients ( embolization at the time ≥72 hours after the onset ).Factors including pre-and post-interventional Glasgow coma score ( GCS ) and Glasgow outcome score , ( GOS) as well as barthel index ( BI ) were statistically compared between the study groups.T-test was performed to compare the data between the two study groups.Chi-square test was taken to evaluate the enumeration data.And the correlation of therapeutic time and prognosis of patients was demonstrated by binary regression analysis.Results In the patients with ruptured intracranial aneurysms at Hunt-Hess Ⅳ-Ⅴlevels, early stage intervention (63.5 ±13.5) resulted in significantly better BI after three months , and demonstrated better recovery in comparison to the late stage intervention group (34.8 ±12.7) ( t=6.127, P<0.05).But no statistical significance of post-operative GCS (6.6 ±1.6 in early therapy group;6.1 ± 1.4 in late therapy group ) and discharging GOS ( 3.0 ±0.7 in early therapy group; 2.9 ±0.7 in late therapy group) was found between the two groups (t=1.822, 0.631 respectively; P>0.05).The early therapy group also presented a significant decrease of complications , such as hydrocephalus (χ2 =6.369, P<0.05 ) and venous thrombosis (χ2 =5.158, P <0.05 ), compared to the late therapy group.Furthermore, Statistical analysis revealed that therapeutic time closely correlated with the prognosis of patients with ruptured intracranial aneurysms at Hunt-Hess Ⅳ-Ⅴ levels ( P =0.009, OR =3.897).Conclusion The early stage therapy can improve the prognosis and decrease incidence of complications , which should benefit the efficient management of the patients with interventional embolization of ruptured intracranial aneurysms.

Object To develop a method for the separation and purification of polyprenyl acetates from the leaves of Ginkgo biloba L Methods Lipids, including polyprenyl acetates were extracted by petroleum ether, and adsorbed by silica gel to remove most of the polar impurities After removing wax from the partially purified extract, it was further purified with silica gel chromatography Results Finally, a mixture of homologues polyprenyl acetate was obtained The purity of which as determined by HPLC external standard method was 84% Conclusion This procedure is simple and relatively effective

Objective To investigate the clinical characteristics,treatment options and prognosis of duplex kidneys in children.Methods Data were retrospectively collected from all patients who were hospitalized at Shengjing Hospital Affiliated to China Medical University from January 2008 to May 201 5.The surgery to retain moie-ty nephron was performed in 30 cases:1 2 cases underwent non common sheath ureter reimplantation,4 cases of the patients had common sheath ureter reimplantation,1 2 patients underwent transurethral resection of the cyst,1 case of them had pyeloureterostomy,and the other patients underwent lower -pole pyeloplasty.Removal of renal moiety was performed in 52 cases:43 patients underwent upper -pole heminephrectomy,8 patients underwent upper pole hemi-nephrectomy and lower -pole ureter reimplantation,and 1 case of the patients had upper -pole heminephrectomy and lower -pole ureteroplasty.Results A total of 54 cases were followed up,the follow -up rate reached 65.9%,the follow -up time lasting 2 months to 4 years,with an average time of 9.53 months.All clinical symptoms disappeared after remove moiety operation.There were small ureteral cysts but compared with the preoperative condition,the symp-toms reduced significantly in 4 cases.All clinical symptoms disappeared in patients whose nephron was retained after operation,and hydronephrosis was alleviated.De novo 2 degree of vesicoureteral reflux was found in 3 out of 1 2 pa-tients who underwent transurethral puncture of the cyst.Conclusions The clinical manifestations of duplex kidney have some characteristics which include recurrent urinary tract infection,normal intermittent voiding urine dripping, abdominal pain,urethral orifice mass,abdominal mass and aggravation of hydronephrosis.Duplex kidney is often asso-ciated with cardiac malformation and cryptorchidism.The preoperative testicular examination and echocardiography should be performed.The choice of operation depends on the clinical manifestation,auxiliary examination results and comprehensive analysis.The prognosis of duplex kidney is well,but patients need to be further followed up af-ter operation.

Congenital hydronephrosis is the main cause of childhood chronic renal disease and renal failure,which is also one of the most common anomalies in pediatric urology division.Although the operation is performed to treat obstruction,the renal function of patients get worse and worse,postoperatively.Up to date,there are lots of controversies in evaluation of hydronephrosis and treatment at prenatal and postnatal.According to recent articles,the recent examinations,evaluation system,follow-up and treatment strategies of hydronephrosis are introduced.

Introducing the current challenges of library of Institute of Information Research, China Rehabilitation Research Center,the paper puts forward the establishment of effective literature resources construction and reader service mechanism. Construction of library collection should be developed from two aspects, namely, the acquisition and integration parts, so as to develop characteristic,compound collections with both printed literatures and digital literatures. Reader service is not only including the traditional service but also covering deep-rooted professional information analysis and multiple types of services.

Objective To investigate the amide proton transfer (APT) values in basal ganglia of neonatal piglet hypoxicischemic brain injury (HIBI) model using MR APT imaging.Methods Totally 35 healthy neonatal piglets were selected.There were 5 piglets underwent sham-operation in control group and 30 piglets used to established HIBI models in HIBI group.According to the time interval between APT imaging and the establishment of HIBI model,the piglets in HIBI group were divided into 0-＜2 h,2-＜6 h,6-＜12 h,12-＜24 h,24-＜48 h and 48-＜72 h subgroups.APT imaging was performed on all piglets.The APT value of basal ganglia between control group and all the subgroups in HIBI group were compared.Results After HIBI occurred,the APT values immediately decreased in 0-2 h,and then increased gradually.In 24 h after HIBI,the APT values were mainly returned to the level of control group,then continuously increased.The APT value in control group and 0-＜2 h,2 ＜6 h,6 ＜12 h,12-＜24 h,24-＜48 h,48-＜72 h subgroups in HIBI group were 0.52 ± 0.09,-0.35 ± 0.08,-0.02 ± 0.14,0.28± 0.04,0.46 ± 0.11,0.80 ± 0.11,1.24 ± 0.18,respectively.The APT values between control group and each subgroups in HIBI group had significant differences (all P＜0.01) except for 12-＜24 h subgroup (P=0.68).Conclusion The APT value decreased firstly and then increased after HIBI in neonatal piglet.APT imaging can provide a non-invasive molecular MR method to evaluate the pathophysiological changes of HIBI.

A simpler method for preparing hap- toglobin from the waste residue of Rivanol- ammonium sulphate fractionation of human serum during the production of human immunoglobulin is described. The agar do- uble diffusion test shows that the large amount of haptoglobin can be prepared by this procedure and the immunoelectropho- resis analysis demonstrated specific preci- pitated line with the reference anti-hapto- globin antibody, showing that the protein molecule of haptoglobin is homogeneous.

In this paper, murine natural killer (NK) cells were studied with cytochemistry and electron-microscopy after treated with interleukin-2 (IL-2) and polysaccharide of astragalus (PA). The results showed that acid phosphatase (AcP), acid naphthylacetate esterase (ANAE) and naphthol-AS-D chloroacetate esterase (NCAE) were positive in NK cells, and the activity of AcP and ANAE was enhanced by IL-2 and PA. Significant changes of NK cells in ultrastructure took place after preculturing with IL-2.

With the continuous development of modern chemistry, biology and pharmacy, researches on TCM modernization has witnessed a wide range of application of related modern technology, especially in researches of TCM monomer efficacy and pharmacokinetics. This can provide basis to internationalization of traditional Chinese medicine. The current research focus is how to obtain targeted TCM monomer. This article expounded the screening methods for TCM monomer at home and abroad, the principles of screening, the limitation and meanings.