1.Analysis of Current Situations and Influence Factors in TCM Research Projects of Nanjing Municipal Hospitals
Chinese Journal of Information on Traditional Chinese Medicine 2014;(7):4-7
ObjectiveBy reviewing TCM research projects in Nanjing municipal hospitals from 2006 to 2010 (eleventh five-year plan), this study aimed to recognize the existing problems, put forward corresponding solutions, and help Nanjing municipal hospitals improve scientific research level.Methods Through field investigations and interviews with experts, this study set 139 research projects from 2006 to 2010 in 10 municipal hospitals in Nanjing as study samples. ResultsDuring 2006-2010, current situations in TCM research projects of Nanjing municipal hospitals were as follows:the number of TCM research projects was small, the research level was low, and the fund was little. TCM research resources were unevenly distributed;the overall quality of TCM human resources were not high;talent structure was unreasonable;great differences existed among different types of hospitals.ConclusionsDuring the eleventh five-year plan period, there were significant differences between TCM research projects and WM research projects in Nanjing municipal hospitals, such as the differences in number, level, fund and project channel. The study proposed that TCM research materials should be rationally allocated, related mechanisms should be perfected, the industrial structure should be optimized, and the pace of training and introducing TCM research human resources should be quickened, with a purpose of making contributions to TCM development in Nanjing.
2.The application value of flupentixol-melitracen after percutaneous coronary intervention
Chinese Journal of Primary Medicine and Pharmacy 2016;23(6):880-883
Objective To investigate the short and long-term effects of flupentixol-melitracen after percu-taneous coronary intervention( PCI) .Methods 86 patients with coronary heart disease who would be given PCI were randomly divided into 43 cases of the study group and 43 cases of the control group.The control group was given conventional treatment after surgery, the study group was given flupentixol -melitracen on the basis of the control group.After one course,the mental status changes and short-term effect were observed.All the patients had been follow-up for 1 year to observe the occurrence of cardiovascular events.Results After one course,the HAMA and HAMD in the study group and the control group were (7.46 ±2.53) points and (15.74 ±3.16) points,(8.03 ± 1.97)points and (16.42 ±3.67)points respectively,which in the study group were lower than the control group (t=13.413,13.208, all P <0.01 ) .The total effective rate of the study group was 97.67%, which was higher than 81.40%of the control group (χ2 =6.081,P<0.05).During follow-up,the incidence rate of adverse cardiovascular events in the study group was 6.67%,which was lower than 42.86%of the control group (χ2 =9.564,P<0.05). Conclusion The flupentixol-melitracen can effectively improve anxiety and depression, improve the recent thera-peutic effect of PCI,reduce the incidence of cardiovascular events,which worthy of promotion after PCI.
3.Acupuncture and Moxibustion Therapy of Unilateral Neglect after Stroke
Chinese Journal of Rehabilitation Theory and Practice 2007;13(12):1196-1197
In accordance with the theory of traditional Chinese and Western medicine and clinical observance, the author explained the cause, mechanism and symptoms of the unilateral neglect after stroke, and summarized the way to treat the unilateral neglect with acupuncture and moxibustion therapy.
4.Normalization and individual therapy in treatment of inguinal hernia
International Journal of Surgery 2010;37(1):51-53
Since the first description of tension-free herniorrhaphy and the developement of prosthetic ma-terial for inguinal hernia, many techniques have come and gone. We should deploy the idea of evidence-based medicine and clinical practice guideline, according to the pathogenetie condition and medical condi-tion, in order to make the best treatment perseription for patient under the condition of nomudization.
5.An Improved Experimental Myocardial Ischemia Reperfusion in Rat Model
Journal of Zhejiang Chinese Medical University 2007;0(01):-
[Objective] To improve the way of establishing myocardial ischemia reperfusion rat model.[Methods]30 SD rats,quality(220?20)g,male,randomly split into normal model group and improved model group,improved established model ligation with a 0.6mm diameter line,and drawn after 30min.Compare such a method with normal model.[Results] In the context of keeping experimental stability,the reduced heart rate,wake time and survival rate of the way of improved established model respectively are(50?20)/min,(15?5)min,86.67%,but it is just(120?20)/min,(80?20)min,66.67% of the normal model group.[Conclusion]The improved myocardial ischemia reperfusion model offers significant superiority to the former one.
6.Advancing research on relationship between stromal cells and the development of tumor
China Oncology 2009;19(10):788-792
Stromal cells are one of the important components of tumor mieroenvironment, which plays an oncogenic role in tumorigenesis. Stromai cells and their products can transform adjacent tissues in the absence of pre-existing tumor cells by inciting phenotypic and genomic changes in the epithelial cells. The research on the tumor-associated-stromal cells will be benefit in clarifying the mechanisms of carcinogenic lesions and investigating more effective therapy methods.
7.Effect of strengthen rosuvastatin in the treatment of patients with paroxysmal atrial fibrillation in coronary artery disease and the influence on serum inflammatory factor
Chinese Journal of Primary Medicine and Pharmacy 2016;23(7):961-964
Objective To observe the effect of strengthen rosuvastatin in the treatment of patients with paroxysmal atrial fibrillation in coronary artery disease and the influence on serum inflammatory factor, to provide reference for clinical treatment.Methods 176 coronary artery disease patients with paroxysmal atrial fibrillation were randomly divided into observation group and control group, 88 cases in each group.The control group was given rosuvastatin,10mg/d,qd.The observation group was given rosuvastatin,20mg/d,qd.The LAD and LVEF were detected by color-Doppler before treatment and after 6 months treatment.The fasting blood was exsanguinated for testing BNP,hs-CRP,TNF-α,IL-6.The incidence rates of sinus rhythm maintenance and embolic events were recorded. Results After treatment,the LAD of the observation group and control group were (41.50 ±4.61)mm and (42.21 ± 5.20)mm respectively,which were significantly lower than before treatment (t=3.959,3.863,all P<0.05),the LVEF were (76 ±6)% and (73 ±5)% respectively,which were significantly higher than before treatment (t =7.744,6.837,all P<0.01),there were no statistically significant differences between the two groups after treatment (t=1.140,0.579,all P>0.05).The BNP,hs-CRP,TNF-α,IL-6 levels of the observation group and control group after treatment were (173.44 ±32.45)ng/L and (203.33 ±42.16)ng/L,(4.54 ±1.34)mg/L and (5.44 ± 1.35)mg/L,(15.34 ±3.26) ng/L and (19.45 ±2.23) ng/L,(10.85 ±0.77) ng/L and (13.27 ±1.23) ng/L respectively,which were significantly lower than before treatment (t=5.855 and 3.533,3.857 and 3.534,6.436 and 4.545,5.743 and 3.925,all P<0.05),the BNP,hs-CRP,TNF-α,IL-6 levels of the observation group after treatment were significantly lower than the control group(t=3.546,3.214,3.176,3.414,all P<0.05).The total effective rate,sinus rhythm maintenance rate,embolic events incidence rate of the observation group and the control group were 93.18%(82/88) vs 79.55% (70/88),68.18% (60/88) vs 43.18% (38 /88),2.27%(2/88) vs 18.18%(16/88).The total effective rate,sinus rhythm maintenance rate of the observation group were significantly higher than the control group (χ2 =11.965,11.144,all P<0.01),the embolic event incidence rate was significantly lower than the control group (χ2 =12.129,P<0.01).Conclusion Strengthen rosuvastatin can effectively reduce the serum inflammatory factors and BNP,improve left atrial remodeling and left atrial function,the clinical efficacy and prognosis are significantly improved, it is worthy of clinical use in the treatment of patients with paroxysmal atrial fibrillation in coronary artery disease.
8.Removing mistake on application of centralized oxygen supply
Chinese Medical Equipment Journal 2003;0(11):-
In order to enable centralized oxygen supply a healthy development,this paper introduces five kinds of mistakes in the application of centralized oxygen supply technique.
9.The Milestones Guidebook of American medical postgraduate education (2016): An interpretation
Journal of Medical Postgraduates 2017;30(8):792-797
The Milestones has become an important component of Graduate Medical Education (GME) of the United States, and the Milestones Guidebook (2016) can help understand and implement the Milestones and improve graduate medical education and practice.This article outlines the basic principles of the Competency-Based Medical Education (CBME) and the Milestones, introduces the guidelines and responsibilities of related stakeholders in Implementing and Using Milestones Effectively, and highlights the Importance of Assessment and Feedback.The Milestones includes 6 core competencies to be achieved in skills, knowledge, and behaviors, its formative process, the causes of its development, and its effective implement and application.The Milestones is the development of CBME and designed to help all practitioners make highly competent physicians.The primary objective of this program is to cultivate trustworthy medical graduates and provide high-quality health care to the general public.
10.Clinical analysis of difference of inferior ST segment change of acute anterior wall myocardial infarction
Xiaomin WANG ; Hiroshi MIYAMOTO
Chinese Journal of Primary Medicine and Pharmacy 2013;20(21):3271-3273
Objective To investigate the clinical characteristics of inferior acute myocardial infarction (IAMI) with different inferior ST segment change.Methods The clinical data of 64 cases with acute anterior wall myocardial infarction from January 2010 to February 2012 in the hospital were prospectivly analyzed.According to wall leads ECG ST segment in the change situation,they were divided into three groups,group A (16 cases),under the wall (]Ⅱ,Ⅲ,aVF) of at least two lead ST segment elevation ≥0.1mV,group B(26 cases) under the wall(Ⅱ,Ⅲ,aVF) of at least two lead ST segment depression,group C (22 cases) under the wall(Ⅱ,Ⅲ,aVF) only a lead or no ST segment change.The infarct related artery,acute anterior wall myocardial infarction with different inferior ST-T change (infarction related coronary artery,IRCA),the infarct size and heart function were studied.Results IRCA in the three groups was consistent.The comparison of IRCA among the three groups showed that,A group of patients with “around the apical LAD” COSCO segment,accounting for 81.25%,and 26 cases in B group were not “around the apical LAD”,which was not “around the apical LAD” in 18 cases,8 cases of non-“ around the apex” COSCO LAD,of 22 patients in C group,21 cases non-“ around the apical LAD”,1 case was “around the apical LAD” COSCO,and the difference was statistically significant(F =6.32,5.92,7.08,4.11,all P < 0.05).Conclusion IRCA is the LAD of acute anterior wall myocardial infarction of inferior ST segment changes may be related with the length of LAD and the lesion site,changes of inferior ST segment of anterior wall AMI can predict the IRCA position and LAD morphology,consistent with most studies.Patients with anterior wall and inferior wall ST segment elevation if IRCA is “around the apical LAD”,the infarction area is smaller,better heart function.