1.Study of 3D visualization methods on PACS workstation.
Xiaomian XIE ; Siping CHEN ; Shuxiang LI ; Zhexing LIU
Journal of Biomedical Engineering 2004;21(3):406-409
Based on a discussion on PACS and the way its image workstation obtains scanned sequential images, this paper presented a method of 3D surface construction and visualization on PACS workstation. Guest/Server structure was used between PACS application entities. Image storing and transmission were realized by service classes established by DICOM standards. Relation database was used to arrange the stored sequential images. Image workstation transformed the sequential images obtained from PACS net into volume data field. 3D reconstruction and rendering results were obtained by using surface-rendering and volume-rendering methods, which made the 3D construction results acquire vivid 3D structure details of high fidelity and strong sense of reality. 3 sets of application results were also presented in this paper.
Humans
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Image Processing, Computer-Assisted
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methods
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Imaging, Three-Dimensional
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Magnetic Resonance Imaging
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Radiology Information Systems
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Tomography, X-Ray Computed
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User-Computer Interface
2.The relation of metabolic electrolyte disturbance and multi-organ functional disturbance on severe actue mountain sickness patients
Bihai ZHENG ; Suzhi LI ; Xun LI ; Yue HUANG ; Chuncheng YAN ; Jianbao ZHEN ; Xiaobo ZHOU ; Xiaomian XIE ; Zeping SUN ; Shangshi LI
Chinese Journal of Endocrinology and Metabolism 2009;25(3):306-307
Electrolyte disturbance was prominent in patients with severe acute mountain sickness. In these patients hypoxia caused water and salt retension together with vasoactive substances and excessive free radicals might play important roles in the development of multiple organ dysfunction syndrome (MODS). More attention should be given to electrolyte monitoring in dealing with these severe mountain sickness in field.
3.Registration and 3D rendering of serial tissue section images.
Zhexing LIU ; Guiping JIANG ; Wu DONG ; Yu ZHANG ; Xiaomian XIE ; Liwei HAO ; Zhiyuan WANG ; Shuxiang LI
Journal of Biomedical Engineering 2002;19(4):628-632
It is an important morphological research method to reconstruct the 3D imaging from serial section tissue images. Registration of serial images is a key step to 3D reconstruction. Firstly, an introduction to the segmentation-counting registration algorithm is presented, which is based on the joint histogram. After thresholding of the two images to be registered, the criterion function is defined as counting in a specific region of the joint histogram, which greatly speeds up the alignment process. Then, the method is used to conduct the serial tissue image matching task, and lies a solid foundation for 3D rendering. Finally, preliminary surface rendering results are presented.
Algorithms
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Image Processing, Computer-Assisted
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methods
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Imaging, Three-Dimensional
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Microtomy
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methods
4.Analysis of Clinical Consistency of Animal Models of Attention Deficit Hyperactivity Disorder Based on Characteristics of Clinical Diseases and Syndromes in Traditional Chinese and Western Medicine
Xinyue XIE ; Xiaomian LIU ; Ming LI ; Mengfei WANG ; Rongyi ZHOU
Chinese Journal of Experimental Traditional Medical Formulae 2025;31(13):270-278
ObjectiveBased on a new method for animal model evaluation, this study aims to analyze the characteristics of diseases and syndromes of existing animal models of attention deficit hyperactivity disorder (ADHD) from both traditional Chinese medicine (TCM) and western medical perspectives and propose suggestions for improvement. MethodsA systematic search of the China National Knowledge Infrastructure (CNKI) and PubMed was conducted for literature on ADHD animal models. According to TCM and western medical diagnostic criteria, core and accompanying symptoms of the models were assigned with scores to comprehensively evaluate the clinical consistency. ResultsThe selection of experimental animals for ADHD models primarily involved rodents, with modeling methods including genetic, chemical induction, and environmental induction. The average consistency of clinical diseases and syndromes with TCM and western medicine was 45.19% and 49.42%, respectively. The spontaneously hypertensive (SHR) rats and nicotine/smoking models had the highest consistency with TCM, while the social isolation models had the highest consistency with western medicine. Most models were guided by western medicine theories, which can meet the surface validity and structural validity requirements of western medicine but lacked precise differentiation of TCM syndromes. ConclusionExisting ADHD animal models primarily focus on a single genotype or environmental factor, lacking comprehensive consideration of multigenic interactions and environmental factors. Moreover, the selection of model evaluation indicators is relatively singular, primarily focusing on "disease" indicators, while TCM "syndrome" indicators have not been fully considered. It is recommended to introduce a "formula-to-syndrome" approach in the preparation of TCM models for ADHD and establish and improve an evaluation system of animal models combining diseases and syndromes, so as to provide a solid foundation for future experimental research.
5.Analysis of Clinical Consistency of Animal Models of Attention Deficit Hyperactivity Disorder Based on Characteristics of Clinical Diseases and Syndromes in Traditional Chinese and Western Medicine
Xinyue XIE ; Xiaomian LIU ; Ming LI ; Mengfei WANG ; Rongyi ZHOU
Chinese Journal of Experimental Traditional Medical Formulae 2025;31(13):270-278
ObjectiveBased on a new method for animal model evaluation, this study aims to analyze the characteristics of diseases and syndromes of existing animal models of attention deficit hyperactivity disorder (ADHD) from both traditional Chinese medicine (TCM) and western medical perspectives and propose suggestions for improvement. MethodsA systematic search of the China National Knowledge Infrastructure (CNKI) and PubMed was conducted for literature on ADHD animal models. According to TCM and western medical diagnostic criteria, core and accompanying symptoms of the models were assigned with scores to comprehensively evaluate the clinical consistency. ResultsThe selection of experimental animals for ADHD models primarily involved rodents, with modeling methods including genetic, chemical induction, and environmental induction. The average consistency of clinical diseases and syndromes with TCM and western medicine was 45.19% and 49.42%, respectively. The spontaneously hypertensive (SHR) rats and nicotine/smoking models had the highest consistency with TCM, while the social isolation models had the highest consistency with western medicine. Most models were guided by western medicine theories, which can meet the surface validity and structural validity requirements of western medicine but lacked precise differentiation of TCM syndromes. ConclusionExisting ADHD animal models primarily focus on a single genotype or environmental factor, lacking comprehensive consideration of multigenic interactions and environmental factors. Moreover, the selection of model evaluation indicators is relatively singular, primarily focusing on "disease" indicators, while TCM "syndrome" indicators have not been fully considered. It is recommended to introduce a "formula-to-syndrome" approach in the preparation of TCM models for ADHD and establish and improve an evaluation system of animal models combining diseases and syndromes, so as to provide a solid foundation for future experimental research.