Objective To discuss the application effects of fast track surgery treatment in hysterectomy. Methods 120 patients underwent hysterectomy. They were randomly assigned to two groups,namely,fast track sur-gery group(60 cases) and control group(60 cases ). two groups underwent separately fast track surgery mode and tradi-tional mode therapy. To observe the duration of passing flatus, the hospital stay, the aching time, the complication rate after operation between two groups. Results All patients got recovery. The duration of passing flatus(29.2±7.9) h,the aching time 96.7% (58/60)、the hospital stay( 3.9±2.5 )d of fast track surgery group were significantly shorter than the duration of passing flatus (50.3±15.8 ) h 、the aching time 8.3% (5/60)、the hospital stay (6.7±2.8 ) d of control group( allP<0.01 ). there was no severe complication in two groups. Conclusion Fast track surgery treat-ment mode could accelerate postoperative rehabilitation of hysterectomy patients. It shoud be popularized.

Objective To investigate the dynamic change of T-lymphocyte subpopulations in the patients with SARS to understand the pathogenesis of SARS,and to find the specific early diagnostic and warning indexes for SARS.Methods T-lymphocytes in the peripheral blood were labelled by specific fluorescein antibodies and examined by flow cytometry in 252 cases of patients with SARS.The relationship between the dynamic change of T-lymphocyte subpopulations and the clinical progression was analyzed.Results The CD 3 +,CD 4 + and CD 8 + T cells,especially CD 4 + T cells decreased at the fist two-week of the disease course and reached to the lowest level at the second week,and began to increase from the third week in all patients.The change pattern of CD 3 +,CD 4 + and CD 8 + T cells in the severe type of SARS was the same as that of the mild type of SARS,but with more serious extent and longer time.The CD 4 + cell amount of the first,second and third weeks in the mild type of SARS was 515?444/?l,421?350/?l and 600?389/?l respectively,and was up to normal level at the fourth week.The CD 4 + cell amount of the first,second,third and fourth weeks in the severe type of SARS was 312?158/?l,255?187/?l,435?343/?l and 539?394/?l respectively,and still lower than normal level at the fourth week.There was a significant difference in the CD 3 +,CD 4 + and CD 8 + cell amount among the different weeks of disease course in both types.NK cell amount also decreased during the course of disease.The CD 4 +/CD 8 + ratio did not change much and was within the normal range.Conclusions The decrease of CD 3 +,CD 4 + and CD 8 + T cells is a sensitive index for early diagnosis of SARS.The continuous decrease of them may indicate the severe condition of the patients with SARS.

ObjectiveTo investigate the effect of N-ras oncogene expression in acute myelogenous leukemia(AML).Methods N-ras oncongene in 10 cases of AML were determined using reverse transcriptase-polymerase chain reaction(RT-PCR).Results 3/10 cases were the positive expression,the positive rates were 30%;2/3 patients were treated to complete remmision(CR).Their N-ras oncogene change negative,1/3 patients was no remmision(NR),his N-ras oncogene change negative,1/3 patient was no remmision(NR),his N-ras oncogene keeps positive and dead after 4 months.Conclusions Determination of the N-ras oncogene expression in AML has worthy for diagnose and prognosis.

Objective To investigate the effect of Propess on cervical collagen remodeling and cervical ripening in full-term pregnancy.Methods 94 cases of mid-term pregnant women enrolled in obstetrics and gynecology of our department from January 2016 to January 2017 were divided into two groupaccording to the random number table method.47 cases of the control group, taking oxytocin intravenous infusion;observation group of 47 cases, taking propess suppository vaginal medication.Labor time, medication to labor time, cervical Bishop score, mode of delivery, postpartum hemorrhage and neonatal situation of two groups were compared.Results Compared with the control group, the Bishop score of the cervix was increased, the total effective rate of cervical ripening was improved, the labor was shortened, the time of medication was shortened, and the delivery rate of vaginal delivery was improved(P<0.05), while the two groups were bleeding, neonatal Apgar score and the incidence of fetal distress were not statistically significant.Conclusion It can promote cervical collagen remodeling, promote cervical ripening, thereby reducing the rate of cesarean sectionwith taking propess in the vaginal.

Objective To observe the effect of ritodrine hydrochloride on peripheral blood and tocolysis rate of patients with threatened premature labor.Methods89 cases of patients with threatened premature labor were selected from October 2015 to September 2016 and randomly divided into two groups, research group with 45 cases treated with ritodrine hydrochloride and control group with 44 cases treated with epsom salt.The peripheral blood, extinction time of uterine contraction, extended days of pregnancy, postpartum hemorrhage, neonatal birth weight and tocolysis rate were compared between two groups.ResultsAfter treatment, CRH, NO, PGE2 and IL-8 of control group were obviously higher than research group, the difference was statistically significant (t=10.826,3.839,7.534,8.075,P<0.05).The extinction time of uterine contraction in control group was obviously longer than research group, while extended days of pregnancy and neonatal birth days in research group were obviously longer than control group, the difference was statistically significant (t=4.566,7.855,3.237,P<0.05).There was no significant difference in postpartum hemorrhage between two groups (t=0.889,P>0.05).The overall efficacy of tocolysis in control group was 70.5%, while that in research group was 86.7%, which was obviously higher than the control group, the difference was statistically significant (χ2=7.801,P<0.05).ConclusionRitodrine hydrochloride can effectively control uterine contraction factor in peripheral blood and extend gestational days of patients with threatened premature labor, so as to improve tocolysis rate and birth quality.

Objective To investigate the correlation of subtypes of the lymphocytes with metabolic syndrome in the aged.Methods 955 aged male and 150 aged female were recruited to a cross-sectional case-control study.CD3+,CD4,CD8+,CD19+,NK cell was measured with flow cytometry.ResultsCD3+,CD19+,NK cells showed no difference in cases and in controls.CD4+/CD8+ ratio declined in subjects with metabolic syndrome,and the ratio declined further with the more criteria.The analysis of multiple analysis regression showed that metabolic syndrome depressed CD4+/CD8+ ratio in the aged.Conclusion Metabolic syndrome was correlated with the disorder of immunity.

Objective: To observe the effect of acupuncture-moxibustion on the expression of insulin-like growth factor-1 (IGF-1) and suppressor of cytokine signaling-2 (SOCS2) in colonic mucosa of rat models of ulcerative colitis (UC), and explore the mechanism of acupuncture- moxibustion therapy in treating UC. Methods: The rats were randomized into a normal control (NC) group, a model control (MC) group, an herb-partitioned moxibustion (HPM) group and an electroacupuncture (EA) group, 8 in each group. The rat models of UC were established by immunological methods combined with local stimulation. The rats in the HPM and EA groups were given herb-partitioned moxibustion and electroacupuncture treatments respectively, once every day, lasting for 14 d. The morphological variations of rat's colonic mucosa were observed under light microscope; the colonic mucosal mucin was detected by PAS-AB and HID-AB staining methods; the expression of IGF-1 and SOCS2 was assayed by the immunohistochemical method. Results: In the rat models of UC, ulceration and inflammation of the colon were revealed by light microscope. The concentration of colonic mucosal mucin was reduced (P<0.01), while the expression of IGF-1 had an increase (P<0.01), and the expression of SOCS2 was reduced (P<0.01). After HPM or EA treatment, the pathological injuries of colonic mucosa had improved, the concentration of mucin increased (P<0.01), the expression of IGF-1 decreased (P<0.01), and the expression of SOCS2 increased (P<0.01). Conclusion: The secretion of mucosal mucin in rat UC decreased, the expression of IGF-1 was significantly higher, while the expression of SOCS2 was remarkably lower; both HPM and EA can help improve the damage of colonic mucosa in rat UC, and modulate the secretion of mucin, as well as regulate the expression of IGF-1 and SOCS2 in the colonic mucosa.

AIM To observe the alteration of the functions and hypermicro-instructure in lung of experimental aging mice and the effect of cistanche desertica polysacchrides on the alteration. METHODS To use the models of inhaling ozone (O 3) for 4 week,and two doses of cistanche desertica polysacchrides (50,100 mg?kg -1 ?d -1 ) were ig administrated to small and large dose group mice per day respectively(for 6 week).Then the behavioral and bio-chemical examinations of lung and blood was carried out,and the ultrastructures were observe by the transmission electronic microscopic. RESULTS Compared with aging models,cistanche desertica polysacchrides could significantly prolong the period of non-oxygen ( P

Objectives:To study the clinical characteristics of myopia in children and the measures to prevent it. Methods:748 patients with myopia were analyzed by refraction examination. Results:By the classification of the causes of myopia, the simple myopia constitutes the majority. By the degrees of the disease, the number of mild myopia was the first and moderate myopia was the second. By the patterns,the amount of compound myopic astigmatism was the majority. The correction of simple myopia or mild and moderate myopia was the most effective way. Of the patients(4～14 years), the age of 12 years had the highest myopia rate. Conclusions:To pay great attention to the prevention works of myopia in grade school years. Correcting refraction exactly and on time is an effective method to slow down the progression of myopia in children.

Objective To analyze the psychometric properties of the Fine Motor Function Measure Scale (FMFM) with cerebral palsied children less than 3 years old. Methods Three hundred and seventy-five children less than 3 years old with cerebral palsy were involved. The test-retest reliability, inter-tester reliability, correlation validity and structural validity of the FMFM were analyzed, as well as the responsiveness. Results The test-retest reliability (ICC = 0. 983 3 ) and the inter-tester reliability (ICC = 0. 992 4) of the FMFM were satisfactory. The correlation index between the raw FMFM scores and scores on the Peabody Developmental Motor Scale——Fine Motor was 0.919 9. The FMFM could clearly distinguish differences in fine motor function between the affected side and the intact side in children with hemiplegia. The differences in fine motor function between children with diplegia and quadriplegia could also be distinguished by the FMFM. The effect size of this scale was also good. Conclusion The reliability, validity and responsiveness of the FMFM were satisfying. The fine motor functioning of children with cerebral palsy could be effectively measured using the FMFM scale.