1.The expression of P-selectin in rats with hepatic ischemia reperfusion injury
Baobao DANG ; Jin DANG ; Xiaomei CHU
Chinese Journal of Primary Medicine and Pharmacy 2011;18(1):44-46
Objective To explore the express of P-selectin in liver-tissue,on the model of HIRI in rats,we explored the pathogenesy of HIRI. Methods 32 female Sprague-Dawley rats were divided into four groups randomly ( n = 8 in each group): sham operation group ( group SO ), ischemia 30 min without repe- rfusion group ( group Ⅰ),30 min reperfusion following ischemia 30 min group ( group IR30 min), one hour reperfusion following ischemia 30min group( group IR1h). The model of HIRI was maded by Pringle's hepatic vascular occlusion. The contents of P-selectin in hepatic tissue were measured by kit of SP. Results After ischemia 30 min,the content of P-selectin in hepatic tissue increased less obviously than group SO; After 1 h reperfusion, the content of P-selectin in hepatic tissue vascular endothelial and hepatocyte express more broadly than group SO. Conclusion The content of P-selectin in hepatic tissue was increased gradually in the process of hepatic ischemia reperfusion injury(HIRI) in rats.
2.Interventional nursing for patients wiih coronary chronic total occlusion by transraidal approach
Yan JIN ; Ying LIU ; Xiaomei YANG
Chinese Journal of Practical Nursing 2009;25(30):4-6
Objective Summarize the interventional nursing experiences for patients with coronary chronic total occlucion by transraidal approach. Methods Preoperative evaluation, careful psychological nursing, perioperative observation and prevetion complications were used for 105 patients with coronary chronic total occlusion when curred by transraidal approach intervention. Results There were 97 cases had successful operation, while 8 cases failure. There were 14 cases of perioperative hypotension, 6 cases of coronary acute occlusion, 4 cases of coronary perforation and 3 cases of no- reflow. There were no radial- as-sociated complication in any patients. Conclusions Effective and careful nursing measures can prevent complications.
3.The clinical effect of zhidanhuayu Decoction on patients with carotid atherosclerotic plaque
Xiaomei MA ; Xuejun WU ; Liying JIN
Chinese Journal of Biochemical Pharmaceutics 2017;37(7):129-130,133
Objective To observe the clinical curative effect of zhidanhuayu decoction on patients with carotid atherosclerotic plaque.Methods 80 patients with carotid atherosclerosis were randomly divided into two groups, each group of 40 cases, the control group was treated with rosuvastatin calcium 20 mg, once every night.The treatment group in the control group on the basis of a scheme based on the use of night zhidanhuayu decoction water 500 mL temperature and heat to 200 mL, then add water and cook until 200 mL to 100 mL, on the afternoon of two phase decoction against half amount of clothes, a daily agent;the two groups were 3 months for 1 courses.Before and after treatment, the mean medial thickness(IMT), plaque score, blood lipid and adverse reactions were observed.Results There was significant difference between the two groups before and after treatment, the difference was significant between the medial and middle thickness(IMT), plaque score and blood lipid(P< 0.05).After treatment, compared with the control group, the treatment group and the control group, IMT, plaque score, blood lipids were statistically significant(P< 0.05).Conclusion Zhidanhuayu decoction can adjust the blood lipids, but also has the effect of anti atherosclerosis.
4.Application of preoperative evaluation checklist in the preoperative preparation of laparoscopic cholecystectomy
Xiaomei WANG ; Mengna WANG ; Jin XIA
Chongqing Medicine 2016;45(8):1029-1031
Objective To explore the effect of preoperative evaluation checklist in the preoperative preparation of laparoscop‐ic cholecystectomy .Methods Based on whether the preoperative evaluation checklist was used or not ,664 cases of patients were di‐vided into control group (n=350) and experimental group (n=314) .Routine preparation was used in the control group ,while the preoperative evaluation checklist made by department of hepatobiliary surgery in the second affiliated hospital of Chongqing medical university was added to the experimental group .The case histories of patients in both groups were retrospectively reviewed ,so as to make comparisons of the defect of preoperative preparation ,influence to operation (delay or cancel) ,comprehension of preoperative knowledge ,and score of degree of satisfaction .Results The incidence rate of the defect of preoperative preparation in the experi‐mental group (1 .59% ) was lower than that in the control group (6 .86% ) with a statistical difference (P<0 .05) .The influence to operation (delay or cancel) in the experimental group was lower than that in the control group with a statistical difference (P<0 .05) .The comprehension of preoperative knowledge and score of degree of satisfaction in the experimental groups were obviously superior to those in the control groups ,which both had a statistical difference (P<0 .05) .Conclusion The application of preopera‐tive evaluation checklist in laparoscopic cholecystectomy could benefit for sufficient preoperative preparation ,conducting surgery as scheduled ,patients′comprehension of preoperative knowledge and patients′satisfaction of medical treatment ,which deserved widely clinical generalization .
5.Analysis of infant-mother attachment and the related influencing factors
Xiuhong LI ; Jin JING ; Desheng YANG ; Xiaomei CAI ; Xuebin CHEN ; Xiaomei SU
Chinese Journal of Tissue Engineering Research 2005;9(40):152-154
BACKGROUND: Attachment reflects the early social experience of infant, which plays an important role in later child development. Although most of the attachment develops between infant and mother, some may occur between infant and care giver or others who have close relationship with it.OBJECTIVE: To analyze the infant-mother attachment patterns and the factors related to infant attachment.DESIGN: It was a sampling investigation.SETTING: Department of Maternal and Child Health, School of Public Health, Sun Yat-sen University.PARTICIPANTS: Totally 75 infants and their mother were selected randomly for this study in the Department of Child Health in Guangdong Maternal and Child Health Hospital from August to October 2002.METHODS: Strange situation test (SST) was performed by 6 researchers who were trained systematically. They watched the videos collectively and classified the patterns of infant attschment based on their performance. The internal consistency coefficient was 0.90. For those inconsistent assessments, the video should be reviewed and discussed to get an accordant conclusion. In addition, a self-designed maternal questionnaire was used to investigate the general condition of the infant and the familial information.MAIN OUTCOME MEASURES: ①Distribution of infant attachment patterns. ②Analysis of the risk factors related to infant attachment.RESULTS: All the 75 infants and their mother entered the statistical analysis. ①Distribution of the infant attachment patterns: In 75 infants, secure attachment was 65% and insecure attachment was 35%, among which,insecure-indifferent type was 18%, insecure-importunate type was 13%,and insecure-disorganized type was 4%. ②Analysis of the risk factors related to infant attachment Those infants with a younger age, a poor approachability (the response to strangers, new environment and objects), a closer relationship with caregiver and a more inconsistent education from the family members, are prone to develop insecure attachment.CONCLUSION: Secure attachment is dominant in infants. The security of attachment is related to the maturity and personality traits of the infants,the relationship between infant and caregiver and the educational approach for them. Key words Object attachment; Infant; Factor analysis, statistics
6.Study on Accurately Controlling Discharge Energy Method Used in External Defibrillator.
Biao SONG ; Jianfei WANG ; Lian JIN ; Xiaomei WU
Chinese Journal of Medical Instrumentation 2016;40(1):17-21
This paper introduces a new method which controls discharge energy accurately. It is achieved by calculating target voltage based on transthoracic impedance and accurately controlling charging voltage and discharge pulse width. A new defibrillator is designed and programmed using this method. The test results show that this method is valid and applicable to all kinds of external defibrillators.
Defibrillators
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standards
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Equipment Design
7.Discuss the SOP in the application of the administration and operation of instruments
Can ZENG ; Shili GUO ; Xiaomei JIN ; Baoqin HUANG
Chinese Journal of Practical Nursing 2015;31(14):1084-1086
Objective To standardize the operation processes of neonatal instrument,ensure the standards effectiveness and safety of equipment use.Methods A retrospective study had been taken on after the developments and implementations of all neonatal instruments standard operation procedure (SOP).The equipment maintenance data were collected and analyzed one year before and after the implementation of SOP.Results After the effective implementation of the SOP,the incidence of instrument repair due to misoperation,improper maintenance reduad by 59%(19/32),9/14,4/7,the instrument management efficiency was enhanced,and the safety of nurses and patients was guaranteed,and the patients satisfaction was improved,and also the quality of care was enhanced.Conclusions SOP procedure plays a very important role in improving neonatal care management and overall efficiency.It makes a continuous improvement of nursing care which is worth widely being implemented.
8.HGF and RAGE expressed in placentas of patients with gestational diabetes mellitus and its relationship with maternal and neonatal prognosis
Sufang JIN ; Xiaomei ZHOU ; Jinchuan FANG ; Yuping GUO
Chinese Journal of Primary Medicine and Pharmacy 2014;(17):2621-2623
Objective To study the expression of HGF , RAGE in placentas of patients with gestational diabetes mellitus and its relationship with maternal and neonatal prognosis .Methods The complete clinical datas of late pregnancy,GDM treated group 40 cases,GDM untreated group 23 cases,the control group 30 cases.Immunohisto-chemical method was used to detect HGF and RAGE in the placentas of three groups ,the maternal and neonatal prog-nosis were recorded.Results In GDM untreated group,GDM treated group and the controlled group placenta ,HGF and RAGE expressed.The expression of HGF was gradually increased ,and any comparative differences between two groups were statistically significant ( F =7.56, P <0.05 );the expression of RAGE in placentas was gradually declined ,the differences among the control group and GDM untreated ,GDM treated group were statistically significant (F=11.62,P<0.05).The rates of maternal and neonatal complications in the GDM untreated group were signifi-cantly higher than that of the GDM treated group and the control group (χ2 =7.34,13.21,9.75,6.67,15.23, 12.53,all P<0.05).Conclusion HGF and RAGE may participate in the occurrence and development of GDM and maternal and neonatal prognosis closely ,regular treatment can improve the prognosis of mothers and infants .
9.Visuospatial Cognitive Characteristics and Behavior Problem in Children with Nonverbal Learning Disabilities
Qingxiong WANG ; Jin JING ; Xiaomei CAI ; Al ET
Chinese Mental Health Journal 1992;0(01):-
Objective:This investigation examined the relationship between visuospatial cognitive char-acteristics and behavior problems in Chinese children with nonverbal learning disabilities.Methods:Partici-pants (N=120, among 6~12 year-old) included children with NLD (N=40) and children with VLD (N=40), as well as comparison normal children (N=40) with no psychiatric history. Participants were assessed with the following measures: the Wechsler Intelligence Scale for Children (C-WISC), Draw-a-person test and CB-CL. The visuospatial cognitive ability and behavior problems were analyzed.Results:The child with NLD showed abnormality in the aspects of spatial ability, visual-movement coordination and speed, sketch percep-tion, vision memory, nonverbal reasoning and vision combination, compared with the other groups (p
10.Study of whole-body bone mineral density measurement in 6 to 19 year-old students in Beijing
Jiachang LIU ; Qiaohong OUYANG ; Jin ZHANG ; Qing LIU ; Xiaomei TENG
Chinese Journal of Radiology 2001;0(05):-
Objective To observe the changes of bone mineral density (BMD) in young boys and girls from 6-19 years old in Beijing area. Methods 1 139 healthy young boys and girls undergoing whole body scanning with dual energy X-ray bone densitometer were divided into different groups according to sex and age. Results There were no significant difference in body height, weight, BMD and bone mineral contents (BMC) between boys and girls from 6 to 10 years old. The annual growth rates of body height, BMD, and BMC were the fastest in girls from 6 to 14 and boys from 6 to 16 years old, respectively. Thereafter, the annual growth rates of body height, BMD, and BMC didn't significantly increase in boys and girls. There were two fast-growth periods in BMD growth stage, being at 11 and 14 years old in girls, and at 12 and 15 years old in boys. The total body BMD was significantly correlated with the height in girls under 12 years (P