Practical education is one of the most important ways to cultivate the medical personnel who has the ability and moral integrity at higher medical schools. To set up a long-term mechanism of practice of educating people, steps should be taken to fully understand the important sense of the times of practical education to medical students, research and construct the scientific system of practical education and protection mechanism, and to carry out diversity of evaluation and assessment.

Objective To investigate the effect of misoprostol on postpartum hemorrhage caused by uterine inertia . Methods 52 cases of uterine inertia maternal postpartum hemorrhage, according to hospital odd and even numbers divided into observation group and the control group, 26 cases in the control group to intramuscular oxytocin 20 u, and intravenous in-fusion of oxytocin 20u; observation group sublingual misoprostol 400 ug.Contrast bleeding 2 h, 24 h after two maternal drug use, changes in blood pressure and hemoglobin, hematocrit decline.Results Observation group has been effectively con-trolled bleeding, hemoglobin and hematocrit decrease than the control group, the difference was statistically significant.(All p<0.05).Conclusion misoprostol treatment of postpartum hemorrhage caused by uterine inertia, the effect is significant.

In order to study the influencing factors of clinical teaching quality,students studying in non-affiliated hospitals,clinical teachers,teaching management personnel in hospitals and university were investigated as study subjects with Delphi Method.Suggestions were put forward that non-affiliated hospitals should improve the construction of the teaching staff,emphasize the teaching management,and strengthen students' education and management for improving clinical teaching quality in non-affiliated hospitals.

The significance of strengthening the construction of teaching staff in non-affiliated hospitals was discussed. Combined with the problems in strengthening the construction of teaching staff, some countermeasures were put forward, such as emphasizing on teaching, enhancing teaching awareness, improving teaching institutions and teaching rules, selecting teaching staff with high standards, strengthening teacher's teaching ability, establishing teaching quality guarantee system and teaching stimulating mechanism.

Objective To explore the upstream signal transduction pathway of neutrophil elastase(NE)-induced mucin(MUC)5AC gene expression.Methods A549 cells were either incubated with NE alone or with DMTU,aprotinin or AG1478.The level of MUC5AC mRNA was measured with RT-PCR.The activation of epidermal growth factor receptor(EGFR) and signaling were assessed by measuring the release of epidermal growth factor(EGF) and the phosphorylation of EGFR.Results NE increased MUC5AC gene expression accompanied by an increase of EGF and phosphorylated EGFR.DMTU,aprotinin and AG1478 significantly inhibited MUC5AC gene expression.DMTU and aprotinin significantly decreased the level of EGF and phosphorylated EGFR.ConclusionNE can induce MUC5AC gene expression via EGFR signalling in A549 cells.The upper stream involves oxidants,activation of tissue kallikrein and EGF.

Objective To investigate the status quo of the medical staff in 6 village clinics in Fengjie County, and to put forward countermeasures and suggestions for improving the quality and overall quality of medical personnel in village clinics. Methods The research literature and questionnaires were used to investigate the basic situation of the village doctors, the role of the village doctors in the residents' health care, and the needs and satisfaction of the residents in the village clinics. The data were analyzed by SPSS 19.0, and the samples were analyzed by descriptive statistics. Results The average age of the medi-cal staff in village clinics was (46.74±10.17) years old, and there was no medical staff under 30 years of age. The medical staff of the village health clinics had an irrational age structure, and the educational back-ground was generally low; the medical staff generally thought that their income was not high. They hope to participate in more training in medical technology; residents generally believe that the doctors' ability to diagnose and treat the disease needs to be improved. Conclusion It is necessary to strengthen the leading role of the government and bring into play the positive work of the medical staff in the village health clinic. It is also necessary to strengthen the training of talents, lay a solid foundation for development, take the demand as the guide to change the service concept and model, to improve the relevant mechanisms to create good surroundings for the development of medical staff in village clinics.

Ensure scientific decision-making by taking the concept of scientific development as the guidance and pooling people’s wisdom.Adhere to the people-centered and create ecological environment.Focus on management innovation to build a new campus.All of these have made the building and development of Jinyun Campus,CQMU,a gratifying result.

OBJECTIVE:To explore appropriate pharmaceutical care methods for hemophilia children,and to improve rational drug use. METHODS:Drug consultation hemophilia records collected from our hospital during Nov. 2014 to Jul. 2015 were summa-rized in respects of personal structure,form and content;key cases were analyzed specially. RESULTS:During Nov. 2014-Jul. 2015,clinical pharmacists received 130 times/cases of medication consultation that related to hemophilia in our hospital;patient’s family members occupied the main part (70.0%);most of drug consultation form was information platform for consultation (58.5%);consultation content mainly covered drug combination and auxiliary medication (77.7%). Clinical pharmacists have re-duced the risk of bleeding,improved the quality of life,reduced the economic burden of families and strengthened the awareness of medical staff and patient’s family member on safe drug use through finding out medication error timely,paying attention to the component of compound drug,guiding medication direction and optimizing therapy plan. CONCLUSIONS:Clinical pharmacists ac-tively provide pharmaceutical care and promote rational drug use during hemophilia treatment from medication consultation,ratio-nal drug use,etc.

Children without company of parents in pediatric intensive care unit,often irritable crying,injured,or scratching themselves,pulling in all kinds of wire and/or catheter on the body,and even adverse events,such as dropping of bed.To ensure the safety of the children,we invent a multifunctional strait-jacket,and it is applied in clinic in order to solve the above problems.The structure of this strait-jacket is open,easy to install wire and all kinds of operation;shoulder,cuff with button loops fix bed guardrail by a rope,to prevent the roll shift;cuff with double fold gloves can avoid scratch the skin,remove the line,having the effect of palm warm;waist adding two constraints,not improving constraints on the waist but abdomen to keep warm.By clinical application,this strait-jacket improves the comfort of the constraint,can prevent the occurrence of complications due to improper constraints,such as skin abrasions,physical damage,blood circulation obstacle,alleviate the pain for the children.