Objective To explore the prevention and treatment principles of different types of iodine contrast agents.Methods 240 patients with CT enhancement were divided into two groups according to the contrast agent type: 80 patients with ionic contrast agent (control group), 160 cases with non-ionic contrast agent (observation group).The allergic reaction was evaluated according to the ADR classification.The constituent ratio of the allergic reaction was observed in the two groups.The contrast ratio of the hypersensitive reaction was observed.The clinical manifestations of the allergic reaction were observed.Results In the control group, there were 8 cases of mild allergic patients,7 cases of mild allergic patients in the observation group,7 cases of moderate allergic patients in the control group,6 cases of moderate allergic patients in the observation group,4 cases of severe allergic patients.There were 2 cases of severe allergic patients in the observation group.In the observation group, there were 15 cases of total allergies and 19 cases of total allergies in the control group.The number of allergies in the observation group was lower than that in the control group (x2=9.063,P<0.05).80 cases of contrast agent induced 19 cases of allergic reaction;non-ionic contrast agent iodopromide 79 cases, induced 9 cases of allergic reactions;non-ionic contrast agent iodohydrin contrast 81 cases.Allergy symptoms such as skin rash, malaise, chills and fever, eyelid edema, throat discomfort and voice, such as nausea and vomiting, dizziness, chest tightness, cardiovascular symptoms such as shock, blood pressure changes and so on.Conclusion Non-ionic iodine contrast agent is superior to ionic contrast agent in the incidence of allergic reaction.However, it is an important measure to reduce the patients' injury caused by different types of hypersensitivity reaction.It is worth the attention of clinicians.

With reference to the research report of American Medical Association on the healthcare system,the paper analyzed the existing medical service,and probed into the causes of poor quality of care The author staged the six countermeasures highlighting patient-focus,safe,effective,timely,efficient and fair medical service models,in the hope of improving quality of care and ensuring patient safety.

Objective: To study whether parental rearing styles of medical students with IAD are related to their mental health, in order to provide foundation for the prevention and control of IAD. Method: Medical students in grade 1 to 4 in Chongqing Medical University were assessed with SCL-90, EMBU, Internet Addiction Disorder Test,and a compare analysis was made for IAD group and non-IAD group. Results: 6.49% subjects can be defined as IAD according to their testing scores of Internet Addiction Disorder Test. The results of EMBU demonstrated that students in IAD group got more punishment, negation and less care or understanding than those in non-IAD group. The results of SCL-90 demonstrated that IAD group got higher scores than non-IAD group. Parental rearing styles of medical students with IAD are related to their mental health. Conclusion: Medical students with IAD got more punishment, negation and less care or understanding,and have lower mental health than those with non-IAD. Negative parental rearing styles of medical students with IAD have bad effects on their development of normal mentality. Parents should pay more attention to their rearing styles.

Objective To investigate the clinical characteristics and diagnosis and treatment of ileocecal disease.Methods The general data,clinical manifestations,imaging examinations,colonoscopy and pathological examination and diagnosis of 134 patients in our hospital with ileocecal disease from September 2009 to March 2016 were collected.The clinical characters were summarized by retrospective analysis.Results A total of 134 cases with ileocecal disease were collected,and 36(26.87％)of them were ileocecal cancer,30(22.39％)of them were inflammatory bowel disease,26(19.40％)of them were intestinal tuberculosis.The main clinical manifestations of ileocecal lesion were abdominal pain,abdominal distention,diarrhea,bloody stool,etc.The colonoscopy imaging showed mucosal hyperemia,edema,erosion,ulcer and tumors on the intestinal tract.The benign lesions mainly showed ulcer with mucosal erosion and edema,and the ileocecal cancer showed neoplasm.CT examination was the common imaging method,and 93(69.40％)cases got tested.49 cases had operation,in which 7 cases had misdiagnosed before operation,and the rate of misdiagnosis was 14.28％.Conclusion The ileocecal disease is mainly benign lesions,and the process of diagnosis is complex;the rate of misdiagnosis is a little high.

When the Internet brings convenience to college students,it has deep influence on their behavior and mind.Internet Addiction Disorder(IAD)has drawn social attention widely.Therefore understanding the harm of IAD,finding out the causes and taking effective prevention and treatment measures are of positive significance to prevent college students' IAD.

ObjectiveTo explore the characteristics and the pathogenetic mechanism of prospective memory in patients with chronic primary insomnia. Methods Forty-two patients with chronic primary insomnia and forty age,gender,education,and cultural level matched healthy adults were assessed with a battery of neuropsychological tests including event-based prospective memory (EBPM)and time-based prospective memory (TBPM) tasks.ResultsCompared with the healthy controls ( EBPM: 5.58 ± 0.35 ;TBPM: 4.10 ± 0.32),the patients with chronic primary insomnia had a significant loss in EBPM (3.44 ±0.40,t =3.933,P =0.000),but a insignificant impairment in TBPM (3.76 ± 0.29,t =0.787,P =0.433 ).The retrospective component of event-based prospective memory between the two groups had no significant difference ( t =1.308,P =0.195 ) ,neither did the retrospective component of time-based prospective memory ( Z =- 0.776,P =0.437 ).ConclusionThese results suggest that the patients with chronic primary insomnia have impairment in EBPM,but not in TBPM and the retrospective component of prospective memory.

ObjectiveTo investigate the relationship between nonalcoholic fatty liver disease(NAFLD)and the severity of coronary artery disease (CAD).MethodsRetrospective cross-sectional studies were conducted to examine the relationship between NAFLD and the severity of CAD. CAD was diagnosed by coronary angiography and NAFLD by type-B ultrasound.ResultsThe logistic regression analysis showed that hypertension, NAFLD, diabetes, smoking, and high level of γ-glutamyltransferase were risk factors of multiplevessel lesions and occlusion of CAD( P＜0.05 or P＜0.01 ) , and high levels of total cholesterol and alanine aminotransferase were risk factors of multiple-vessel lesions ( P＜0. 05 or P＜0.01 ) , family history was a risk factor of occlusion of CAD, whereas, high level of high-density lipoprotein cholesterol was an important protective factor of multiple-vessel lesions and occlusion of CAD ( P＜0. 01 ). NAFLD was a dependent risk factor of multiple-vessel lesions and occlusion of CAD( P＜0.05 or P＜0. 01 ). ConclusionsNAFLD could be regarded as a main risk factor of the severity of CAD. Clinicians should pay more attention to the prevention and treatment of NAFLD in order to improve the outcome of CAD.

Pituitary adenoma, a benign intracranial tumor, is the third most common brain tumor, second only to glioma and me-ningioma. Pituitary adenoma has been defined as a benign tumor, but some pituitary adenomas can invade the surrounding tissue. This tumor is difficult to resect and can easily recur after surgery. RWD-containing sumoylation enhancer (RSUME) can stabilize the activity of hypoxia-inducible factor-1α and inhibitor kappaB by the small ubiquitin-related modifiers. This phenomenon indicates the impor-tance of RSUME in pituitary adenoma because it promotes the invasiveness of the tumor. However, the correlation between RSUME and the invasion of pituitary adenoma remains unclear. In this study, the roles of RSUME on HIF-1α/VEGF signaling pathway and IκB/NF-κB compomers in the invasiveness of pituitary adenoma were reviewed.

Objective To investigate into the indications and related anatomic foundation of transjugular intrahepatic portosystemic shunt(TIPS) creation by direct transcaval approach in patients with portal hypertension cirrhosis suffering unusual anatomy between the hepatic veins and portal bifurcation; and to evaluate the security, feasibility and clinical significance. Methods Direct transcaval approach TIPS were performed in 65 patients including active variceal bleeding (n=52), intractable ascites (n=12), and as a bridge to liver transplantation (n=1). Results Technical and functional success were achieved in all patients. The success rate was 100% without related complications including the technique and primary patency rate is obvious higher than classical TIPS. Conclusion In patients with unusual anatomy between the hepatic veins and portal bifurcation, and inaccessible or inadequate hepatic veins, transcaval TIPS creation is secure and feasible. The results suggest that the direct transcaval approach offering favorable primary patency because the shunt has a straight line in construction.

Objective To find a new algorithm for oscillometric blood pressure measurement. Method A coefficient difference comparative method was proposed to measure the difference of adjoining pulse waves and their comparative ratios. And the turning point was judged by priority way in the range. Result The new method settled the problem of miscarriage of justice of the turning point around average pressure and improved the accuracy of blood pressure measurement. Conclusion It can detect difference between cardiovascular patients and normal persons. And it is effective and reliable in blood pressure measurement. It provides a convenient method for researching, preventing and epidemiological studies of cardiovascular diseases in our country.