1.Diagnosis and treatment progress of children′s food allergy correlative persistent diarrhea
Chinese Journal of Applied Clinical Pediatrics 2015;(19):1449-1452
Food allergy ( FA ) often leads to protracted diarrhea and chronic diarrhea, which influence children′s nutrition and growth seriously and early diagnosis and treatment is particularly important. Its pathogenesis includes IgE mediated,not IgE mediated,and mix. Mainly manifestations include:food protein mediated rectum colitis, food proteins mediated enterocolitis syndrome,food proteins mediated bowel disease,and coeliac disease ( CD) . Diagnosis should be asked for details of the history. Diet avoidance and open food challenge tests help determine the diagnosis. Treatment mainly for suspicious foods to avoid,breastfeeding should be continue,mothers need to avoid food allergies, artificial feeding should be changed to extensively hydrolysed protein formula( eHF) or amino acid-based formula( AAF) feeding. Try not to use of antibiotics,and to give support therapy. Early diagnosis and treatment,correct nutritional gui-dance can prevent serious complications,reduce its incidence.
2.Investigation on the Effect and Mechanisms of Tea Polyphenols on Lung Injury Caused by Global Cerebral Ischemic-reperfusion
China Pharmacy 2005;0(17):-
OBJECTIVE: To investigate the protective effects of tea polyphenol (TP) on lung injury caused by global cerebral ischemic-reperfusion and its mechanism. METHODS: Improved Pulsinelli-brierley method was applied to induce damage model by global cerebral ischemia model for 15 min and global cerebral ischemia-perfusion for 3 h. Some indexes were observed, including morphology change of cerebral and lung tissue, activity of superoxide dismutase (SOD), concentration of malondialdehyde (MDA) and expression of lipopolysaccharide receptor CD14. Healthy rats were divided into sham group, model group and nimodipine group. RESULTS: As compared with sham group, there were pathologic damage of lung and brain and the positive expression of CD14 cell of lung in model group. As compared with model group, the activity of SOD were increased significantly (P
3.Expression and significance of cyclinB1 and CDK1 in gastric cancer
Chinese Journal of Current Advances in General Surgery 2004;0(05):-
Objective:To investigate the clinicopathological significance of the CyclinB1 and CDK1 expression in stomach carcinogenesis.Methods:The expression of CyclinB1 and CDK1 was examined by immunohistochemistry method in normal epithelium(15 cases),low-differentiated adenocarcinoma (15 cases)and moderate-well-differentiated adenocarcinoma (20 cases).Results:Immunoreaction to Cyclin B1 and CDK1 was mainly localized in the cytoplasm of cells.In stomach carcinogenesis,the positive immunostaining rate of CyclinB1 protein in normal epithelium and adenocarcinoma was 13.3%(2/15),94.3%(33/35) respectively (P
4.Species and Drug Resistance of the Bacteria Isolated from Sputum Specimens of Inpatients in Our Hospital
China Pharmacy 1991;0(05):-
OBJECTIVE:To study the species and drug resistance of the bacteria isolated from sputum specimens of the inpatients in our hospital.METHODS:The drug susceptibility of 2 255 strains of pathogenic bacteria cultured from 6 052 qualified sputum specimens that collected from inpatients of our hospital between Jan.2005 and July 2007 were analyzed retrospectively.RESULTS:Of the 2 255 strains of pathogenic bacteria,1 210(53.7%)were gram negative bacillus,with Pseudomonas aeruginesa,Escherichia cob,Klebsiella pneumoniae and Acinetobacter showing the highest proportion,accounting for 19.5%,13.9%,8.2% and 6.4%,respectively;429(19.0%)were gram positive coccus,with CN-S and Staphylococcus aureus showing the highest proportion;and the 519(23.0%)were fungus with Candida albicans showing the highest proportion.CON-CLUSION:The result of drug susceptibility test showed that both gram negative bacilli and gram positive coccus were highly resistant to quite a few of antibiotics.
5.Prevention and treatment principles of different types of iodine contrast agents
Chinese Journal of Primary Medicine and Pharmacy 2017;24(11):1685-1688
Objective To explore the prevention and treatment principles of different types of iodine contrast agents.Methods 240 patients with CT enhancement were divided into two groups according to the contrast agent type: 80 patients with ionic contrast agent (control group), 160 cases with non-ionic contrast agent (observation group).The allergic reaction was evaluated according to the ADR classification.The constituent ratio of the allergic reaction was observed in the two groups.The contrast ratio of the hypersensitive reaction was observed.The clinical manifestations of the allergic reaction were observed.Results In the control group, there were 8 cases of mild allergic patients,7 cases of mild allergic patients in the observation group,7 cases of moderate allergic patients in the control group,6 cases of moderate allergic patients in the observation group,4 cases of severe allergic patients.There were 2 cases of severe allergic patients in the observation group.In the observation group, there were 15 cases of total allergies and 19 cases of total allergies in the control group.The number of allergies in the observation group was lower than that in the control group (x2=9.063,P<0.05).80 cases of contrast agent induced 19 cases of allergic reaction;non-ionic contrast agent iodopromide 79 cases, induced 9 cases of allergic reactions;non-ionic contrast agent iodohydrin contrast 81 cases.Allergy symptoms such as skin rash, malaise, chills and fever, eyelid edema, throat discomfort and voice, such as nausea and vomiting, dizziness, chest tightness, cardiovascular symptoms such as shock, blood pressure changes and so on.Conclusion Non-ionic iodine contrast agent is superior to ionic contrast agent in the incidence of allergic reaction.However, it is an important measure to reduce the patients' injury caused by different types of hypersensitivity reaction.It is worth the attention of clinicians.
6.One case of Gongylonema pulchrum infection in esophagus in human
Chinese Journal of Schistosomiasis Control 2017;29(1):126-126
This paper reports one case of Gongylonema pulchrum infection in the esophagus in human.
7.Practice of PBL teaching method in political theory course
Chinese Journal of Medical Education Research 2012;11(1):77-79
Implementing PBL teaching in the political theory course,making sure the scientific nature of the problem setting are the fundamental guarantees of the right track of political theory education.There are several specific approaches to implement the PBL teaching effectively:leading up to the problem when teacheing in the large class; completing the analysis and research by dividing groups; carrying out class discussions by teams; submitting discussion experiences by each student.Practice has proved that,PBL teaching is better than LBL one.
8.Effect of enteral nutrition on the improvement of the nutritional status and prevention of complications in elderly stroke patients with eating difficulties
Chinese Journal of Postgraduates of Medicine 2014;37(10):43-45
Objective To investigate the effect of enteral nutrition on the improvement of the nutritional status and prevention of complications in elderly stroke patients with eating difficulties,and provide theoretical guidance for clinical treatment.Methods Eighty-two cases of elderly stroke patients with eating difficulties after stroke were randomly divided into two groups by the time of admission,41 cases in control group were given with parenteral alimentation,and 41 cases in treatment group were given with enteral nutrition.Before treatment and 3 weeks after treatment triceps skinfold (TSF),arm muscle circumference (AMC),serum hemoglobin (Hb),albumin (ALB),serum total protein (TP),high density lipoprotein cholesterol (HDL-C),low density lipoprotein cholesterol (LDL-C),triglycerides (TG),total cholesterol (TC) and fasting plasma glucose (FPG) was measured,and the incidence of complications was observed.Results The TSF,AMC,Hb,ALB,TP,HDL-C,LDL-C,TG,TC and FPG after 3 weeks treatment in control group was significantly lower than that before treatment (P < 0.05),but in treatment group compared with that before treatment there was no significant difference (P > 0.05).The TSF,AMC,Hb,ALB,TP,HDL-C,LDL-C,TG,TC and FPG after 3 weeks treatment in treatment group was significantly higher than that in control group (P < 0.05).The incidence of complications in treatment group was signifcanfly lower than that in control group [36.6% (15/41) vs.78.0% (32/41)] (P < 0.05).Conclusions Enteral nutrition is conducive to the nutritional status of elderly stroke patients with dysphagia improvement,and can greatly reduce the incidence of complications,and improve survival rate.It is worthy of promotion.
9.Evaluation of nursing effects of evidence- based nursing in improving life quality and emotional situation of patients with gastric cancer during perioperation
Chinese Journal of Practical Nursing 2011;27(11):36-38
Objective To study the effects of evidence-based nursing in improving life quality and emotional situation of patients with gastric cancer during perioperation. Methods 96 patients with gastric cancer in our hospital from October 2007 to November 2010 were selected as research object,and all the patients were randomly divided into the control group and the observation group with 48 cases in each group,then the compliance therapy,degree of satisfaction, Kamofsky score,spitzer score, SAS score,SDS score,HAMA score and HAMD score of the two groups before and after surgery on the first,seventh day and first month were analyzed and compared. Results The compliance therapy and degree of satisfaction of the observation group were both better than those of the control group,the Karnofsky score and spitzer score of the observation group after surgery on the first, seventh day and first month were higher than those of the control group,SAS score,SDS score,HAMA score and HAMD score of the observation group were better than those of the control group. Conclusions The effects of evidence-based nursing in improving life quality and emotion situation of the patients with gastric cancer during perioperation is better,and it is worthy of popularization and application.
10.Efficacy analysis of intravenous thrombolysis after cardiopulmonary resuscitation for patients with acute myocardial infarction and cardiac arrest
Chinese Journal of Geriatrics 2014;33(3):232-234
Objective To explore the clinical value of intravenous thrombolysis in the treatment of patients with acute myocardial infarction (AMI) and cardiac arrest after cardiopulmonary resuscitation.Methods 120 patients with AMI and cardiac arrest admitted in our hospital from Mar 2009 to Mar 2013 were divided into thrombolytic group (n=50) and control group (n=70) according to the voluntary principle.The recanalization rate,return time of spontaneous circulation,left ventricular ejection fraction (LVEF) and creatine kinase-MB (CK-MB),complications and hospital mortality rate were compared between two groups.Results The recanalization rate was significantly higher in thrombolytic group than in control group (76% vs.11.4%,x2 =84.81,P< 0.05).Restoration of spontaneous circulation was significantly shorter and LVEF after one week of treatment and CK-MB peak were significantly higher in thrombolytic group than in the control group (t=6.796,4.342,2.923,respectively,P<0.001 or 0.05).The incidences of heart failure,angina,arrhythmia,and re-infarction were significantly lower in thrombolytic group than in control group (x2 =6.10,20.95,8.52,11.10,respectively,all P<0.05).There were no significant differences in the incidences of intracranial hemorrhage and upper gastrointestinal bleeding between thrombolytic group and control group (x2 =2.19,3.74,both P>0.05).Hospital mortality rate was significantly lower in thrombolytic group than in control group (10 % vs.25.7 %,x2 =4.65,P<0.05).Conclusions Intravenous thrombolysis has a higher recanalization rate,faster recovery time of spontaneous circulation,fewer complications and higher hospital survival rate for the treatment of cardiac arrest in patients with acute myocardial infarction after cardiopulmonary resuscitation.