1.Impact of SDG on blood glucose and blood lipid concentrates of middle and old aged female patients
International Journal of Traditional Chinese Medicine 2011;33(1):5-7
Objective To investigate the influence of SDG on blood glucose and blood lipid concentrates of middle and old aged patients. Methods The impacts of SDG on blood glucose and blood lipid concentrates in body of patients with hyperglycemia were conducted through an 8-week random and double-blind experiments with controlled group only given placebo. The influence degree of SDG on blood glucose and blood lipid concentrates of the selected patients was analyzed. Results The results showed that serum glucose of the groups received 400mg/d of dietary SDG for 8 weeks or 600 mg/d for 4 weeks decreased significantly compared with the controlled group (P<0.05). Conclusion Giving either 400 mg/d of dietary SDG for 8 weeks or 600 mg/d for 4 weeks to patients could significantly decrease the serum glucose concentrates of them.
2.Relationship of emergency department length of stay with outcome of multiple trauma patients admitted to ICU
Ligang YE ; Yongan XU ; Xiaojun HE ; Mao ZHANG
Chinese Journal of Trauma 2014;30(8):798-802
Objective To evaluate the relationship between emergency department length of stay (EDLOS) and outcome of multiple trauma patients in ICU.Methods A retrospective cohort study was performed in multiple trauma patients admitted from the emergency department to ICU during 2010.Patients' data were recorded,including demographic information (gender,age,etc.),characteristics of injury (injury causes,diagnosis,ISS,GCS,emergency operation rate,type of operation),and outcome (inhospital mortality,length of ICU stay,total length of hospital stay,expenditure).Patients were assorted into delayed group (EDLOS > 6 h) and non-delayed group (EDLOS ≤ 6 h),then demographic information,characteristics of injury,and outcome were compared between the two groups.Multivariate Logistic and linear regression analyses were performed to identify the correlation between EDLOS and outcome for all patients and for those with and without emergency operation.Results A total of 476 patients aged (47.5 ± 16.0) years were enrolled in the study and male patients accounted for 73.5%.Median ISS was 29 points (interquartile range,22-34 points),median EDLOS was 4.0 hours (interquartile range,2.8-6.4 hours),and inhospital mortality was 9.2%.Delayed (n =135) and non-delayed (n =341) groups were similar in age,gender,ISS,inhospital mortality (13.3% vs 7.6%),length of ICU stay,and total length of hospital stay (P > 0.05).Multivariate analysis demonstrated prolonged EDLOS increased inhospital mortality (OR=3.19,95% CI 1.28-7.95,P < 0.05),especially in patients without emergent operation (OR =4.01,95% CI 1.31-12.27,P < 0.05).However,prolonged EDLOS produced no effect on mortality in patients with emergent operation (OR =1.72,95% CI 0.79-3.43,P >0.05),length of ICU stay,total length of hospital stay,and expenditure.Conclusion Prolonged EDLOS increases mortality of multiple trauma patients admitted to ICU,especially in patients without emergency operation,thus rapid transportation of these patients from emergency room to ICU will improve the outcome.
3.Surgical management of unsuspected gallbladder carcinoma after laparoscopic cholecystectomy
Xin CHEN ; Xiaojun ZHOU ; Zhongqi MAO ; Haixin QIAN
Chinese Journal of Postgraduates of Medicine 2010;33(14):6-8
Objective To investigate the surgical management of unsuspected gallbladder carcinoma (UGC) after laparoscopic cholecystectomy ( LC ). Method The clinical data of 11 cases of UGC incidently found after LC from October 2003 to August 2009 were retrospectively analyzed. Results According to Nevin staging, 2 cases were stage Ⅰ , 6 cases were stage Ⅱ , 2 cases were stage Ⅲ and 1 case was stage Ⅳ.Four cases were treated by LC,including 2 cases with stage Ⅰ and 2 cases with stage Ⅱ ;another 7 cases were treated by radical resection after LC. All patients were followed up for 1-66 months after operation, 2 cases with stage Ⅰ were observed alive up; 2 cases with stage Ⅱ treated by LC died less than 3 years after operation, 3 of the 4 cases with stage Ⅱ treated by radical resection were alive up, only 1 died in 21 months after operation; 2 cases with stage Ⅲ died in 8 months and 10 months respectively, 1 case with stage Ⅳ died in 1 month after operation. Conclusions It is difficult to diagnose the UGC preoperatively. LC is sufficient for patients with Nevin stage Ⅰ , radical resection after LC is required for patients with stage Ⅱ or more advanced stage. If tumors are located in the neck of gallbladder, radical resection is required regardless of their stage.
4.Multislice CT characteristics of coronary atherosclerotic plaques in acute coronary syndrome
Dingbiao MAO ; Yanqing HUA ; Hao WU ; Xiaojun GE ; Guozhen ZHANG
Chinese Journal of Radiology 2009;43(9):928-930
nclude positive vascular remodeling,low plaque density,spotty calcification,and eccentric stenosis.
5.Clinical characteristics and prevention of myopia in children
Suhua WANG ; Xiaomei ZHU ; Xiaojun MAO ; Lin SHI
Journal of Medical Postgraduates 2003;0(11):-
Objectives:To study the clinical characteristics of myopia in children and the measures to prevent it. Methods:748 patients with myopia were analyzed by refraction examination. Results:By the classification of the causes of myopia, the simple myopia constitutes the majority. By the degrees of the disease, the number of mild myopia was the first and moderate myopia was the second. By the patterns,the amount of compound myopic astigmatism was the majority. The correction of simple myopia or mild and moderate myopia was the most effective way. Of the patients(4~14 years), the age of 12 years had the highest myopia rate. Conclusions:To pay great attention to the prevention works of myopia in grade school years. Correcting refraction exactly and on time is an effective method to slow down the progression of myopia in children.
6.Day-case laparoscopic cholecystectomy: analysis of 59 consecutive patients
You HU ; Xin CHEN ; Zheng ZHU ; Lu XU ; Jun YIN ; Xiaojun ZHOU ; Zhongqi MAO
International Journal of Surgery 2017;44(1):20-23
Objective To evaluate the feasibility and outcome of laparoscopic cholecystectomy as a overnight procedure in China.Methods The data of 59 consecutive patients who had undergone outpatient laparoscopic cholecystectomy between Januaiy 2013 and January 2015.All the patients were operated in the morning hours and discharged during 24 hours after operation.They were contacted by telephone 3 days subsequent to surgery and were seen in the outpatient unit 7 days after.Results Fifty-nine laparoscopic cholecystectomies were performed.No Conversion to open surgery case.The average operation time was 25 minutes,and restore semi-liquid diet 6 hours after the operation All the 59 patients were discharged during 24 hours after operations.None of the patients had an emergency readmission.None of the patients had complications 7 days after discharged.The average payment was 8 240 yuan.Conclusion These results suggest that laparoscopic cholecystectomy can be routinely performed as a overnight procedure.
7.Comparison of localizing motor area before the surgery based on resting-state functional MRI with independent component analysis and electric cortical stimulation
Xiaojun SUN ; Jianhua YUAN ; Dewang MAO ; Han ZHANG ; Shuda CHEN ; Zhongxiang DING ; Yumei LI
Chinese Journal of Radiology 2017;51(5):334-338
Objective To evaluate the accuracy of presurgically resting-state fMRI(rs-fMRI) with subject order-independent group independent component analysis(ICA), compared to electric cortical stimulations. Methods Twenty-three patients with the lesion in motor area, which were recorded by our hospital from Jan, 2014 to Dec, 2015, were collected as the study sample. The data of 9 patients were excluded because of excessive head motion. As a result, 14 patients were included in this study. Rs-fMRI data before the surgery and the results of electric cortical stimulations were collected. Results All of this 14 patients were preoperatively located by rs-fMRI with SOI-GICA, including all the SMA and the ipsilesional primary motor area. On the side with lesion, the number of functional location of motor area was decreased compared with healthy side. Evaluate the accuracy of ICA by comparing the coincidence rate of these two techniques, based on the standardized electrical cortical stimulation in operation. The completely concordance between rs-fMRI with the SOI-GICA and electrical cortical stimulation in operation was 11 (11/14). Meanwhile the basically concordance of corresponded case was 3(3/14). Conclusions Rs-fMRI with the ICA has a relatively high accuracy rate in localizing motor area. Rs-fMRI has a remarkably referential contribution to the presurgically function assessment and surgical planning in implementation.
8.Study on the value of focused abdominal sonography for trauma used by emergency doctor in emergency department
Yucai HONG ; Mao ZHANG ; Xiaojun HE ; Shanxiang XU ; Shenhua WANG ; Zhixiong LU ; Jianxin GAN ; Shaowen XU
Chinese Journal of Emergency Medicine 2010;19(10):1066-1069
Objective To study the value of focused abdominal sonography for trauma (FAST) used by emergency doctor in emergency department. Method It's a prospective,double-blinded and controlled study from June 2008 to October 2009. A total of 97 casualties with severe multiple trauma, 72 male and 25 female aged from 14 to 88 years old with average age of (41 ± 16) ,admitted to emergency department were enrolled, and the bedside focused abdominal sonography for trauma was performed by emergency doctor. It was diagnosed as positive if free fluid was detected in abdomen or pericardium. The severe injury scores (ISS) were from 14 to 38 with average score of (23.2±9.3). The criteria of inclusion were age over 14 years old, injury happened within 12 hours and casualties admitted directly into emergency room. The criteria of exclusion were death of patients within 2 days without CT scanning of abdomen and exploration of abdomen with laporotomy, and operations directly determined by using FAST without conventinal sonographic examination. The FAST was compared with CT and conventional sonography judged by the findings observed during operation. Results The examination with FAST was completed in (3.18±0.79) min, whereas that with conventional sonography was (16.63t4.62) min(t = 28.61,P <0.001). The FAST was positive in 11 cases and negative in 86 cases, whereas the conventional sonography was positive in 13 cases and negative in 84 cases ( P = 0.5). There were 4 false negative findings in FAST resulting in 73% sensitivity, 100% specificity, 95.3% negative predictive value, 4.6% false negative rate, 100% positive predictive value, 0% false positive rate and 95.9% accuracy. Conclusions The emergency doctors are able to operate the FAST well for casualties with multiple trauma in emergency department after proper training.
9.Clinical application of continuous subcutaneous insulin infusion in elderly type 2 diabetic patients
Jindan WU ; Jianhua MA ; Xiaohua XU ; Xiaojun TAO ; Dongmei LI ; Xiaoming MAO ; Shaokang QI
Chinese Journal of Geriatrics 2008;27(8):567-569
Objective To explore the application of continuous subcutaneous insulin infusion (CSII) in elderly type 2 diabetic patients. Methods Elderly group(n = 415) and control group (n= 461) received the transient CSII intensive treatment. The different regiments and the incidence of hypoglycemia were observed between the two groups. Results The average duration reaching the target blood glucose and the insulin dosage at the target time were similar between the two groups (P>0.05). The insulin basal rate in the elderly patients was lower than that in control group. The incidence of hypoglycemia, especially at night, was significantly higher in the elderly patients.Conclusions CSII could control blood glucose effectively in elderly type 2 diabetic patients, but the basal insulin dosage should be decreased to reduce the risk of hypoglycemia.
10.The impact of virtual hepatectomy and computer-assisted risk analysis on surgical planning and intraoperative strategy for major hepatic resection
Xiaojun ZHOU ; Lei QIN ; Haixin QIAN ; Jun YIN ; Zhongqi MAO ; Weiguo ZHANG ; Liang GUO
Chinese Journal of Hepatobiliary Surgery 2013;(2):93-97
Objectives To evaluate the impact of virtual hepatectomy and computer-assisted risk analysis on surgical planning and intraoperative strategy for major hepatectomy.Methods Twentytwo consecutive patients (17 males and 5 females) were admitted to the hospital from January to December in 2010 for complicated major hepatectomy.CT scanning was performed with 64-MSCT.All the data of imaging were transferred to the Myrian(R) XP-Liver system (IntrasenseR,France).The following steps were undertaken by a radiologist and a surgeon majoring in liver surgery: step 1,image analysis and 3-D reconstruction; step 2,virtual resection and liver volumetry; step 3,computer-assisted risk analysis for hepatic dysfunction,followed by adjustment of the operative planning.Results The three-dimensional reconstruction models of the liver by the Myrian(R) XP-Liver system were visualized.The ideal simulation effect was achieved comparing the virtual imaging with the actual operation.Of the 22 patients who underwent complicated major hepatectomy,complete tumor removal (R0 resection) was achieved in 20 patients.There were 2 patients who received a R1 resection as microscopic tumor cells were found at the cutting margin of the right portal vein and bile duct.No patient died during the hospital stay.After computer-assisted risk analysis,the operative planning and surgical strategies were changed in 6 patients.Conclusions The application of the hepatic three-dimensional reconstruction and virtual hepatectomy using the Myrian(R) XP-Liver system provided important preoperative data for good preoperative planning and intraoperative strategy in complex hepatectomy.