1.The efficacy of isoflurane supplemented with ropivacaine for sacral block in indirect inguinal hernia
Chinese Journal of Primary Medicine and Pharmacy 2012;19(1):27-28
ObjectiveTo observe the effcacy of isoflurane supplemented with ropivacaine for sacral block in indirect inguinal hernia.Methods120 cases of children who were going to be operated in inguinal hernia repairs were randomly divided into isoflurane group( A),ropivacaine group( B ),and isoflurane supplemented with ropivacaine group(C).Sacral block was performed after induction with different anesthetics.Haemodynamics( MAP、HR 、SpO2 ) in three groups were compared,and anesthesia effect,waking time,drug dosage and adverse reactions were analyzed.ResultsHaemodynamics in isoflurane supplemented with ropivacaine group were more stable than the other two groups,and anesthesia effect was better than isoflurane group and ropivacaine group( all P <0.05).Moreover,waking time,drug dosage and adverse reactions in group C were statistical differently conpared with controls( all P < 0.05 ).ConclusionIsoflurane supplemented with ropivacaine for sacral block was helpful for respiration and circulation management applied in indirect inguinal hernia and could be a perfect anesthetic methods.
2.Vision impairment and eye diseases in the elderly: a report from a community health center
Chinese Journal of General Practitioners 2011;10(2):122-123
The dada of 987 out-patients aged 60 or over,who visited Bajiao Community Health Center of Beijing Shijingshan District from January 2006 to December 2009,were retrospectively analyzed.The results revealed that there was no gender difference in the prevalence of low vision and blindness ( χ2 =2.719,P = 0.606); the severity of low vision and blindness was correlated with the age of patients ( χ2 =138.389,P = 0.000); cataract was the main cause of low vision and blindness,accounting for 49.6%(62/125) of low vision and 64.3% (36/56) of blindness.
3.Combined coronary and renal angiographies through transradial approach
Chinese Journal of Postgraduates of Medicine 2010;33(10):35-38
Objective To investigate the feasibility and safety of combined coronary and renal angiographies through transradial approch.Methods Three hundred and twenty patients in hospital from August 2007 to April 2009 who underwent combined coronary and renal angiographies through transradial approach were included in this study.Renal artery angiography of 300 cases was done by 5 FMP-A1 catheter (MP-A1 group),and 20 cases was done by TIG catheter (TIG group).Control group had 625 patients in hospital from January 2004 to April 2009 who underwent combined coronary and renal angiographies through transfemoral approach.The achievement ratio,operating time,dosage of contrast agent and complication of angiography were observed.Results The achievement ratio was higher in MP-A1 group [97.0%(291/300) ]and control group [98.4%(615/625)]than that in TIG group [40.0%(8/20)](P< 0.01).The operating time was (32.21 ± 3.37) min and the dosage of contrast agent was (52.72 ± 7.91) ml in MP-A1 group,and it was (30.78 ± 3.23) min and (51.88 ± 7.22) ml in control group respectively.There was no significant difference between two groups(P>0.05).The operating time was (26.42 ±4.31) min and the dosage of contrast agent was(51.72 ± 10.11) ml in TIG group.There was significant difference in the operating time between TIG group and the others groups (P < 0.05).The complications of angiography through transradial approach (0.9%,3/320) were less than those through transfemoral approach (3.0%,19/625) (P <0.05).Conclusions Renal artery angiography through transradial approach by 5 F MP-A1 catheter(125 centimeter) is safe and has minor complication.The achievement ratio of transradial approach for renal artery angiography by 5F MP-A1 catheter is higher than that by TIG catheter.
4.Effects of materials and types of biliary tract stents on implantation effectiveness: Enhancing patency rate and prolonging patency time
Chinese Journal of Tissue Engineering Research 2010;14(16):2991-2994
BACKGROUND:Biliary tract stents comprise two types:expanding metallic stents and plastic stents,the patency time of the former is shorter than the latter,but the cost is higher.Thus,it is dispute which kinds of stent should be selected.Accordingly,it becomes a research topic how to improve patency rate and prolong patency time using cheap stents.OBJECTIVE:To explain the progress of biliary tract stents and to explore the effects of materials and types of biliary tract stents on patency rates and patency times.METHODS:The Chinese Journal Full-text Database and Medline were retrieved by the first author using search terms of "biliary stent,metallic stent,plastic stent,occlusion and stricture" both in Chinese and English.Meta analysis or repetitive studies were excluded.After that,20 documents concerning the effects of materials and types of biliary tract stents on patency rates and patency times were analyzed.RESULTS AND CONCLUSION:Biliary stent implantation is the preferred way for alleviative treatment of malignant obstruction of bile duct with few complications.Biliary tract stents comprise two types comprise metallic stents and plastic stents,the biocompatibility of both stents need to be improved.The metallic stents exhibited advantages in preventing bacteria,maintaining stent patency and reducing complications,but the high cost limited its application.Though plastic stents easily lead to stent occlusion due to bacteria adhesion and biliary siltation,however,it has merits of easy change and cheap cost.The combination of biliary stent implantation and radiotherapy can prolong effective patency period and prevent stent occlusion.The results demonstrated that biliary stent implantation is best methods for treating malignant obstruction of bile duct,and combined biliary stent implantation with radiotherapy can prevent stent obstruction.
5.Maintenance of RO processing system used in hemodialysis machine
Chinese Medical Equipment Journal 2004;0(09):-
The operating principle,system structure and influencing factors for water quality are expounded and the maintenance of RO processing system is introduced.
6.Progress on mechanism of hyperhomocysteinemia resulting in atherosclerosis
Parenteral & Enteral Nutrition 1997;0(02):-
Homocysteine(Hcy) is a kind of sulphur-containing amino acid, the intermediate product of the methionine metabolism. It has been shown that hyperhomocysteinemia(HHcy) is a new, indispensable and independent risk factor of atherosclerosis and thrombus diseases by many epidemiological studies, but the mechanism is still not clear. We reviewed the research progress on HHcy causative factor, its relation with cardiovascular and cerebrovascular diseases, the mechanism of its resulting in atherosclerosis, to provide evidence for formulating reasonable schedule of treatment.
7.Discussion on empiric therapy of Invasive fungal infection
Chinese Journal of Practical Internal Medicine 2003;0(01):-
The big trouble for invasive fungal infection(IFI)is how to define the diagnosis.Delayed therapy is the main reason of the death in the IFI patients,which underlines the importance of empiric therapy.Both cost-effectiveness ratio and patients' particular status should be considered when choosing an antifungal drug.Amphotericin B,Itraconazole,voriconazole,caspofungin and micafungin are all recommended.But there are still plenty of questions unanswered about empiric therapy,for example,how to establish th therapy based on scientific evidence.
8.Human tumor-related protein hyrdC: prokaryotic expression,antibody preparation and its preliminary detection in gastric cancer
Academic Journal of Second Military Medical University 1985;0(06):-
Objective:To prepare pure prokaryotically expressed protein of hyrdC and the monoclonal antibody against hyrdC,and to detect the hyrdC protein in gastric cancer with the prepared monoclonal antibody.Methods: The target DNA sequence of hyrdC was obtained by RT-PCR and subsequently inserted into prokaryotic expression vector pET32a.The TRX-hyrdC fusion protein was purified and was used to immunize 6-week-old BALB/c female mice to prepare monoclonal antibodies.The supernants of hybridoma cells were screened by enzyme-linked immunoabsorbent assay(ELISA) and identified by Western blot.The prepared monoclonal antibody was used to detect the expression of hyrdC protein in gastric cancer and adjacent normal tissues by immunohistochemical method(SP).Results: The sequence of hyrdC ORF was conformed to the reported in GenBank.Two lines of hybrids secreting monoclonal antibodies against hyrdC were established,both belonging to IgG2a subtype.Western blot showed that the prepared monoclonal antibodies specifically combined with human hyrdC protein.Immunohistochemistry(SP) results showed that the expression of hyrdC protein in gastric cancer was significantly higher than that in normal gastric mucous membrane(P
9.Research evolution of relationship between DD, vWF, AT-Ⅲ and acute leukemia
Journal of Leukemia & Lymphoma 2012;21(6):376-377,384
The injury of vascular endothelium,activation of coagulation and exist of fibrinolysis in patients with acute leukemia caused the coagulation disorders.It would appear hypercoagulation status or thrombosis,and the incidence was about 10 %- 40 %.It appeared in the early phase of this disease,chemotherapy or infection,and may have no clinical symptoms or signs.The routine coagulation index was also very difficult to detect this hyper coagulation state.Therefore,monitoring in different phrase the content of plasma AT-Ⅲ,vWF and DD in acute leukemia provided the evidence for early diagnosis,prevention and cure of acute leukemia.
10.Establish the hematopoietic stem cell transplantation system with Chinese characteristics
Journal of Leukemia & Lymphoma 2013;22(6):321-324,326
Hematopoietic stem cell transplantation (HSCT) is an effective and sometimes the only curative therapy for patients with certain hematological diseases.HSCT has been practiced in China for approximately fifty years,and great improvements have been made within the past decade,especially in fields such as haploidentical HSCT system,strategies to overcome relapse and GVHD.This review will describe the current situation and provide a prospective of these novel characteristics of HSCT system in China.