Since the first session of Chinese anti-inflammatory immunopharmacological society in 1982,many breakthroughs of immunological research have been made in western countries,such as identification of pathogens by natural immune cells,regulation of immune response,lymphocyte differ?entiation and development. At the same time,much progress has been achieved in anti-inflammatory and immunological research in China,especially in the field of basic scientific issues in immunology, frontier and hot topics,immunological mechanisms of major diseases and related drugs. The course of development of Chinese anti- inflammatory immunopharmacological research has experiences various stages,such as ″follow ″ in the past to ″work together ″ and to ″lead ″ in some research areas in today′s international immunology.

OBJECTIVE: To define the future tasks of pharmaceutical care in asthmatic patients in order to improve pharmaceutical care. METHODS: A questionnaire survey was conducted on 70 outpatients with non-controlled asthma and the data obtained were analyzed statistically. RESULTS: 20.00% of the patients investigated used only controller medications and 10.00% used only reliever medications; 30.00% showed good compliance; 43.28% were able to distinguish controllers from relievers in their own treatment regimens; the proportions of patients who didn't correctly use steroid containing metered-dose inhaler, reliever containing metered-dose inhaler, steroid containing turbuhaler and steroid containing accuhaler were 36.00%, 44.00%, 27.78%, and 23.81%, respectively; 14.29% of the patients kept an asthma diary but none was up to standard; 12.85% owned a peak flow meter; 88.57% judged their treatment outcomes only by symptoms; 51.43% were not aware of any adverse drug reactions of asthmatic medications. CONCLUSION: Asthmatic patients need to be more familiar with their medications. Meanwhile, they need to improve their medication compliance, inhalation technique and self management. Pharmacists should cooperate with other health care professionals and asthmatic patients to improve the asthma control standard in China.

OBJECTIVE: To study the situation of the combined application of Chinese patent medicine with western medicine, and to promote rational and safe drug use. METHODS: The combined application of some commonly used Chinese patent medicines with the western medicines was analyzed by tabulation. RESULTS: Hospitals, retail pharmacies and patients lacked understanding of the situation of the adverse reactions caused by the joint application of the Chinese patient medicines with the western medicine. It is common for the two used in combination. CONCLUSION: Physicians, nurses, pharmacists and patients should familiarize with the effective components contained in the Chinese medicine and the western medicine and be cautious in the joint application of Chinese medicine with the western medicine.

BACKGROUND:Stem cel transplantation is a promising treatment for type 1 diabetes mel itus. Adipose-derived mesenchymal stem cel s have become another hotspot fol owing bone marrow mesenchymal stem cel s.
OBJECTIVE:To investigate the therapeutic effect of adipose-derived mesenchymal stem cel transplantation on type 1 diabetes in a rat model.
METHODS:Forty-five Sprague-Dawley rats were randomized into normal, model and cel transplantation. Animal model of type 1 diabetes was made in the latter two groups through intraperitoneal injection of streptozotocin. Seven days after modeling, rats in the three groups were given intraperitoneal injection of normal saline, serum-free DMEM or adipose-derived mesenchymal stem cel suspension, respectively. Two weeks after injection, body mass, blood glucose level, insulin secretion and PDX-1 mRNA in the pancreatic tissue of rats were monitored and detected in the three groups.
RESULTS AND CONCLUSION:After modeling, the body mass of rats were lowered, and increased gradual y in the cel transplantation group at 2 weeks after cel transplantation, but it was stil decreased in the model group. Compared with the normal group, the fasting blood glucose level was significantly higher in the model group (P<0.05), but it was reduced significantly after cel transplantation (P<0.05). Compared with the normal group, the insulin level was reduced significantly in the model group (P<0.05), but it was increased significantly after cel transplantation (P<0.05). Highest and lowest PDX-1 mRNA expressions were obtained in the normal and model groups, respectively;and there was a significant difference between groups (P<0.05). Al these findings show that adipose-derived mesenchymal stem cel transplantation relieves hyperglycemia in rats by promoting the expression of PDX-1 in the rat pancreatic tissue.

The iodine deficiency disorders surveillances were performed in different historical periods according to different surveillance plans in China as various monitoring purposes.Compared with other editions of surveillance plan,the biggest changes were to observe the urinary iodine level,the salt iodine level and the goiter rate in children and pregnant women in the county level in this National Iodine Deficiency Disorders Surveillance Plan (the 2016 edition).In this paper,the implementation details on this surveillance plan were further interrelated,which would play an instrumental role for the staff in iodine deficiency disorders prevention and control.

Objective To analyze the results of anti‐Treponema pallidum antibody (anti‐TP) in the inpatients to provide the ba‐sis for the prevention and control of syphilis .Methods The results of anti‐TP test among 50 011 patients in our hospital from Jan . 2013 to Nov .2015 were retrospectively analyzed .Results Of 50 011 detected inpatients ,1 360 cases were anti‐TP positive with the total anti‐TP positive rate of 2 .72% ,in which the male positive rate was 3 .22% (719 cases)and the female positive rate was 2 .32%(641 cases) ,the difference was statistically significant (P< 0 .05) .The neonates ,populations aged ≥80 years old and 40 - < 60 years had higher anti‐TP positive rate ,which were 3 .67% ,3 .62% and 3 .24% respectively .The inpatients with anti‐TP positive were mainly concentrated in the surgical departments ,totally 916 cases(67 .35% ) ,in which the general surgery department had the highest anti‐TP positive detection rate(20 .51% ) ,while 444 cases(32 .65% ) of anti‐TP positive were in the non‐surgical depart‐ments .Among the inpatients with anti‐TP positive ,520 cases(38 .24% ) had the positive titer in the serum TRUST .Conclusion Syphilis infection situation is serious ,the routine anti‐TP detection in inpatients has an important significance for preventing nosoco‐mial infection and reducing the medical dispute .

Breast milk is the most natural and healthy food for newborns.Human milk studies show that there are individual differences in milk production and its compositions.Some maternal disease can affect milk quality and quantity,and even health lactating mother's milk does not keep still.It can be found in studies that fatty acid,protein,lactose,microbiology,cell factors and so on can be influenced by many factors from lactating mothers without diseases,such as nurse meals,mood and living habits.To help nursing mothers to provide more high-quality milk for the baby,realize better breastfeeding,characteristics of breast milk components and influence factors of healthy mothers will be discussed.

Objective To study the effects of early rehabilitation with stroke patients by applying Snyder hope theory in clinical nursing. Methods A total of 76 acute stroke patients from Henan Province Hospital of Traditional Chinese Medicine were divided into two groups by random digits table method:experimental group and control group, 38 cases in each group. The final effective cases were 72 and 36 cases in each. The control group received routine care, while those in the experimental group accepted nursing intervention with Snyder hope theory based on routine puncture care for 4 weeks. Herth Hope Index(HHI), National Institute of Health Stroke Scale(NIHSS), Barthel Index(BI) and adherence score before and after 4 weeks were evaluated and compared between 2 groups. Results Before intervention and 4 weeks after intervention, the experimental group of patients with hope level score respectively (31.61 ± 1.95), (40.67 ± 4.01) points, NIHSS scores respectively (18.27 ± 5.31), (10.41 ± 4.21) points, BI scores respectively (37.19 ± 3.31), (46.12 ± 3.51) points, and adherence of functional exercise scores (0.97 ± 0.31), (2.81 ± 0.52) points. The differences were statistically significant (t=17.765-52.571, all P<0.01). There were statistically significant differences with hope level, NIHSS score, BI score before intervention and 4 weeks after intervention in the control group (t=5.435, 4.929, 11.067, all P<0.01), except for adherence of functional exercise scores (t=1.220, P=0.231) in the control group, but the change not as the experimental group. Compared with the control group, there were statistically significant in the score of hope level, NIHSS score, BI score and adherence of functional exercise with the experimental group after intervention ( t=6.030-10.690, all P<0.01). Conclusions The nursing with Snyder hope theory can promote the progress of early rehabilitation of acute stroke patients as well as the patients′exercise adherence.

Strengthening the protection of intellectual property of scientific academies and institutes is not only an important task facing scientific institutions but also an issue demanding the attention of hospital managers. The author explained in the first place the significance of intellectual property protection and pointed out some problems that exist currently in China in this aspect. Then he put forward some measures for strengthening intellectual property protection. These include: ①enhancing the awareness of intellectual property protection; ②attaching importance to the differentiation between property rights of service inventions and those of non service inventions; ③rendering intellectual property protection systematic; ④earmarking funds for intellectual property protection and stressing centralized management of intellectual property protection by specialized departments.

The paper analyzes the problems in the clinical use of antibiotics, including imperfection in the structure of medical personne's professional knowledge, lack of guidance by pharmaceutical personnel about the use of antibiotics, and lack of effective supervision measures on the part of the hospital. It then points out the various harmful consequences resulting from the abuse of antibiotics. It is necessary to strengthen administrative intervention at various levels, to set up a steering committee for the rational use of antibiotics in medical institutions at various levels, and to incorporate knowledge about the rational use of antibiotics and hospital infection into continuing medical education.