98%.Thick myofibers were observed by transmission electron microscopy after induction with 5-aza.Four weeks after transplantation,the left ventricle ejection fraction,the movement extent of left ventricle,left ventricle systolic wall thickening and dp/dt of rabbits were all higher than those of the control group and cardiac infarction model group(P

ObjectiveTo explore the sleep quality and psychical health of the patients with cancer.Methods96 cancer patients were tested by Pittsburgh Sleeping Quality Index(PSQI) and Symptom Check List 90 (SCL-90). ResultsThe PSQI scores of the patients with ache were higher than that without ache (P<0.05).Sleep problems were occurred in 87.55% of the patients. Sleep quality of 9.38% of patients were poor. The sleep quality of the male patients were better than those of the female (P<0.05). Apart from interpersonal sensitivity, paranoid ideation and psychoticism, scores of the rest were higher than the general people(P<0.05).10.2% of the patients with cancer had psychical problems. Apart from sleep time and using sleep pill, there was a high correlation between the scores of SCL-90 and PSQI (P<0.05). ConclusionThe results showed that sleep problems of the patients with cancer affected their psychical health.

Myeloid-derived suppressor cells (MDSCs) play an important immunosuppressive role during the tumor development process.And the progression of many tumors are always accompanied with abnormal accumulation of MDSCs.Moreover,both the accumulation and functions of MDSCs could be affected by complicated factors.Therefore,how to effectively reduce the immunosuppressive effects of MDSCs in oncotherapy has become the focus of scholars.Recent studies show that anti-tumor drugs can affect many biological behaviors of MDSCs.

After a brief description of standards for HL7 and its application in foreign countries and China, the lo-calization and implementation principles of HL7-based application of integrated medical information system, and its advantages and disadvantages were analyzed with its development trend in China pointed out.

Objective To explore how to perform effective health management for the metabolic syndrome(MS) in the health examination center. Methods A total of 153 subjects diagnosed with MS and the same number of healthy controls were analyzed. All patients received health management for 12 months and an impact evaluation was conducted. Results Waist circumference, IBM, SBP, DBP, blood lipids of MS group were remarkably higher than those in normal control group, and there was statistical significance (P

Hair from 16 scalps of different ages (from 5 months to 77 years old) have been observed with SEM. The surface ultrastructure of the cuticle of the hair shaft is distinctly seen. The cuticles are arranged like shingles. Their free margins direct toward the end of the hair. The appearance and diameter of the shaft vary from age to age. The hair shaft of fetus is very fine. The cuticles are so broad that a single cuticle may encircle the shaft. They are parallel to each other. The intervals between successive free margins of cuticles are wide. Their free margin is smooth. The hair shaft of a 5-year old child is coarse. The cuticles vary in size. It requires a number of cuticles to encircle the shaft. The free margin becomes jagged and curved with microprotrusions on it. The intervals between free margins of the cuticles vary in width. The hair shaft of the youths is coarser. The cuticles are broad and arranged regularly. The intervals between free margins of the cuticles are comparatively narrow. There are numerous well developed microprotrusions on the free margin. The hair shaft of the middle aged is the coarsest and the intervals between free margins of the cuticles are the narrowest of all. There are less microprotrusions than those of the youths'. They are getting less and less, so that the free margin is partly smooth. Many cracks perpendicular to the free margin appear apparently and much debris fallen from the cuticle is attached to the surface of the the shaft. Sometimes falling of a whole cuticle may be observed. The hair shaft of the aged people is finer than that of the youths'. The intervals between cuticles with loose squamous arrangement are wider than those seen in the young and middle aged people. The free margin is usually smooth with only a few microprotrusions if any. Sometimes big and deep holes may be found on the surface of white hair. It is considered that the diameter of hair shaft, the size and arrangement of cuticles, the characteristic structures of free margin, the number of microprotrusions and with or without small debris attached to or holes appeared on the shaft are all related to age.

Objective: To study the effect of Mg 2+ onc fos, c jun, p53 and ref 1, that are transcription factors related to redox regulation, in cultured human umbilical vein endothelial cell. Methods: Imunohistochemistry techniques and image analysis system were used. Results:In the group of H 2O 2, the expresson of c fos, c jun, p53 and ref 1 was increased compared to the normal control group (P

Objective: The effects of magnesium on the oxidation of low density lipoprotein (LDL) were systematically investigated by two different oxidation systems. Methods: LDLs were isolated from pooled healthy human fresh sera by ultracentrifugation. Oxidation of LDL was induced by adding Cu 2+ or co-cultured with cultured human umbilical vein endothelial cells. Conjugate diene was measured to assess the susceptibility of LDL to oxidation. The extent of LDL modification was determined by measuring the formation of thiobarbituric acid reaction substances (TBARS). Results: (1)The presence of Mg 2+ resulted in a protracted lag phase at doses of 0.3 mmol/L, 0.6 mmol/L, 1.2 mmol/L, and 2.4 mmol/L, as well as decreased production of TBARS when LDL was oxidized by the addition of Cu 2+ , at doses of 0.3 mmol/L and 0.6 mmol/L Mg 2+ .(2)Treatment of LDL with Mg 2+ (0.3 mmol/L, 0.6 mmol/L, 1.2 mmol/L, and 2.4 mmol/L) reduced the production of TBARS during endothelial cell-mediated LDL oxidation, P

Objective To compare heparin binding protein (HBP)and procalcitonin(PCT)in the evalua-tion of in prognosis of patients with sepsis in ICU.Methods 80 sepsis patients were selected.According to the sever-ity of the disease,they were divided into general sepsis group (n =31),severe sepsis group (n =29)and death group (n =20).The differences of HBP and PCT in three groups were compared.Results Compared with HBP and PCT in the general sepsis group[(3.91 ±0.36)ng/mL,(1.26 ±0.35)ng/mL)],PCT of the severe sepsis group (11.81 ± 0.54)ng/mL was significantly increased(F =2 777.87,P =0.000);HBP and PCT of the death group[(15.28 ± 1.21 )ng/mL,(36.68 ±0.36)ng/mL)]were significantly increased compared with the general sepsis and severe sep-sis groups (F =49 789.02,P =0.000).Conclusion The sensitivity of PCT was significantly higher than HBP in the groups,PCT was better in judging the prognosis of sepsis.