Since 1960s,total parental nutrition(TPN) has had a great development,while complications after long term of TPN has also been recognized.This article reviews intestinal permeability changes after TPN,its possible mechanism and some recent research progresses.

Objective To explore the clinical value of radioactive iodum131 in treating hyperthyroidism.Methods 53 patients with hyperthyroid heart disease were treated with radioactive iodum131. The caring measure before and after the iodum131 treatment was introduced,including psychological and dietary caring,follow-up visit. Results After 12 months iodumted131 treatment, 39 cases were clinical healed ( healing rate 73.58% ), 10 cases (18. 87% )were remitted,4 cases (7. 55% )were inefficient, total effective rate was 92. 45%. Conclusion High quality caring has important clinical significance in safely and effectively developing iodum131 treating hyperthyroid.

Chinese traditional surgery, an important branch of traditional Chinese medicine, has contributed greatly to the people's health in the history. With the fast development of modern medicine, Chinese traditional surgery is faced with serious challenges and its shortcomings have appeared more and more evident. In this article, the authors analyzed some problems in the development of Chinese traditional surgery and the opportunities for its further development, and suggested that the superiorities of Chinese traditional surgery should be enhanced in its future development.

Objective Through an investigation and analysis of the using situation of anti-infectious medicine for the patients of ICU in hospital,to provide guidance for the rational antimicrobial use in clinic and strengthen the level of clinical doctors′reasonable use of the medicine. Methods The anti-infectious medicine used for the patient of ICU in hospital is analysed in respect to defined daily dose (DDD),drug utilization index(DUI). Results An overwhelming majority of anti-infectious medicine′s utilization is reasonable,but 52.4% of the anti-infectious medicine is over the demand of DUI≤1.The result of the DDDs:the Chemical Synthesis′s capacity(32.14%),the aminoglycosides(13.62%),the ?-Lactams and their?-Lactamase inhibitors(13.20%),the antifungal agents(12.66%),the cephalosporins(9.52%).The fuloroquinolones,the third and the forth cephalosporins and the carbapenems are used broadly.The medicine's unit-rate gets 92%,and six unit is the most of all.It can be seen from the category and distribution of the use of anti-infectious medicine that the cephalosprins is the first.The antimicrobial resistance is developed rapidly.The antimicrobial resistance of levofloxacin is 54.45%,then gentamicin is 51.78% and ampicillin,ciprofloxacin,cefazolin,ceftriaxone,SMZco are more than 40%. Conclusions In choosing the dose with the normal regulation(not the dose of indication),doctors consider less for the factors such as the age,medicine interacion,dose of indication,etc.Using the broad-spectrum usually led to many universal phenomenon such as antimicrobial resistance,bacteria migrated and antimycotic infection,etc.That makes double infection(32%) which can't be neglected.The theory of medicinal economics is less used in the clinic practices.

Objective Depending on the analysis of patients who were diagnosed as Community-Acquired Pneumonia in our hospital during 2004-2005, we compared with 《Directory for Diagnose of Community-Acquired Pneumonia》(Draft) in order to provide the guidance for the rational antimicrobial use in clinic. Methods Using the Retrospective Analyze method,we analyzed the cases which included: Name, Sex, Age, time during in hospital, Fees, Medicine and Note. Results Compared from 2005 with 2004, the top 3 ranks of the DDDs in 2004 were cefoperazone sodium/sulbactam sodium;L-ofloxacin ; etimicin and in 2005 were L-ofloxacin; cefoperazone sodium/sulbactam; etimicin. The rate of medicine fees were decreased,but the unites to use medicine,the average time in hospital and the average medicine fees were not deferent remarkable. Conclusions After 《Directory for Diagnose of Community-Acquired Pneumonia》(Draft) was carried out,the condition of application was more rational in 2005 than in 2004, but there were still many problems should be improved.

At present,the main method for data process is to eliminate or save the data,and stale data is seldom reutilized.In this article,the author makes a method that using data warehouse to manage stale data.It can utilize the character of data warehouse to manage stale data and to find the rule in the stale data.

OBJECTIVE:To prepare the scutellarin-PEG-PLGA drug-laded nanoparticles,optimize the formulation with ratio of colostrum and external aqueous phase,mass concentration of scutellarin and PEG-PLGA as factors and conduct quality evalua-tion. METHODS:A double emulsion-solvent evaporation method was adopted to prepare the scutellarin-PEG-PLGA nanoparticles. With the evaluation index of encapsulation efficiency,single factor and orthogonal test were used to determine the apparent shape, particle size,Zeta potential,drug loading amount,encapsulation efficiency and stability of prepared nanoparticles by optimized for-mulation with ratio of colostrum and external aqueous phase,mass concentration of scutellarin and PEG-PLGA as factors. RE-SULTS:The ratio of colostrum and external aqueous phase was 1∶15 and the mass concentrations of scutellarin and PEG-PLGA were respectively 10 mg/ml and 15 mg/ml in optimized formulation;the prepared nanoparticles were round or oval with the average particle size of(78.54±2.21)nm,Zeta potential of(-23.07±1.39)mV,drug loading amount of(1.67±0.12)%,and encapsula-tion efficiency of(45.32±1.29)%. There was no obvious changes in the particle size and encapsulation efficiency within 3 months at 4 ℃ preservation. CONCLUSIONS:The scutellarin-PEG-PLGA nanoparticles with better physical and chemical properties and stability are successfully prepared.

Objective To study the value of the ovarian cyst treated with sclerotherapy under CT guiding. Methods Forty-five cases with ovarian cyst treated with sclerotherapy under CT guiding. Results 36 cases were all cured and other 8 cases reduced and 1 cases was not changed. Conclusion This study suggests that the method of ovarian cyst treated with sclerotherapy under CT guidance is uncomplicated and curative effect.

OBJECTIVE:To analyze disease burden of antibiotic associated colitis(AAC)in patients with severe traumatic brain injury,and to explore prevention and treatment countermeasures. METHODS:Retrospective analysis method was used to analyze the relationship between the occurrence of AAC in 157 cases of severe traumatic brain injury and application duration,dosage and category of antibiotics. RESULTS:Overuse of antibiotics was closely associated with the occurrence of AAC,especially cephalosporins(P

The main factors which affect the farmers'participation in the new rural cooperative medical service are the problems,which exist in the system of the rural cooperative medical service,the institutions of medical service,the government and the farmers themselves etc.Only by constituting the corresponsive policy measures according to these factors can the farmers actively participate in the new rural cooperative medical service.