1.Experimental Study on Tongmai Oral Liquid Prepared by Different Processes
Chinese Traditional Patent Medicine 1992;0(12):-
Objective: To study various preparation methods for Tongmai Oral Liquid. Methods: Tongmai Oral Liquid with ultrafiltration method, water alcohol method, talcum powder method, and method were prepared respectively; using impurity clearing efficency, clarity, total saponin content as parameters for quality control. Results: Tongmai Oral Liquid prepared by water alcohol method (alcohol concentration being 75%) was better than that by other methods in claerity, and stability and has highest total saponin. Conclusions: Quality of Tongmai Oral Liquid prepared by water alcohol method was available.
2.Studies on chemical constituents from leaves of Diplopanax stachyathus
Chinese Traditional and Herbal Drugs 1994;0(02):-
Object To study the chemical constituents from leaves of Diplopanax stachyathus Hand Mazz aiming at searching for bioactive natural products Methods The compounds Ⅰ-Ⅹ were isolated by a combination of Sephedex LH 20 and silica gel column chromatographies, and their structures were identified by spectral methods Results Ten known compounds were isolated from leaves of D stachyathus Their structures were identified by means of spectroscopic analysis as: ? sitosterol (Ⅰ), betulinic acid (Ⅱ), oleanolic acid (Ⅲ), ursolic acid (Ⅳ), daucossterol (Ⅴ), quercetin 3 O ? D glucopyranoside (Ⅵ), 3,3′,4′ tri O methyellagic acid (Ⅶ), 3, 3′ di O methylellagic acid 4 O ? D xylopyranoside (Ⅷ), 3′ O methylellagic acid 4 O ? D xylopyranoside (Ⅸ), and 3, 3′,4′ tri O methylellagic acid O ? D glucopyranoside (Ⅹ) Conclusion Compounds Ⅰ-Ⅵ and Ⅸ are isolated from this plant for the first time
3.FTA/PCR Detection for Cryptosporidium Added in Beverage
Chinese Journal of Parasitology and Parasitic Diseases 1987;0(02):-
An established FTA/PCR protocol was applied to detect Cryptosporidium oocysts which were added in beverage, and proved to be as sensitive as 1.0 oocyst/ml detected within 6 hours. The study indicates that this technique is sensitive, time-saving and easy to perform.
4.Thinking on application of military stress in China
Academic Journal of Second Military Medical University 1985;0(06):-
Based on a retrospective review of researches on military stress home and abroad,this paper elaborates on the following4important issues:the promptness of selected literature,the advance of stress theories,the objectivity of the methods and the practicability of the results. [
5.Analysis on the dangerous fact that influences hypertensive disease jiang xiaohong yan huizhong.
Chinese Journal of Practical Internal Medicine 2006;0(S1):-
Objective By checking on the government employees and teachers.measuring the blood pressure according to WHO,and sending the inquires papers on dangerous fact.Methods The civil servants and teachers in Dangling dis- trict were examined in October 2004.Results The result was made according to the statisitics analysis.It shows that occupation,sex,age,BMI,the history of smoking,the history of family.All these can cause the independent dan- gerous fact to the hypertensive disease.Conclusion Fat,high salt diet,smoking and drinking were all risk factors of high blood pressure.
7.The prevalence and risk factors of coronary heart disease combined with chronic kidney disease
Xiaohong SANG ; Shufang YAN ; Yan SUN
Chinese Journal of Internal Medicine 2012;51(2):123-126
ObjectiveTo investigate the prevalence rate and risk factors of inpatients with coronary atherosclerotic heart disease (CHD) combined chronic kidney disease (CKD).MethodsAll people who underwent CHD combined CKD in CHD department of the First Affiliated Hospital of Xinjiang Medical University during January to December 2009 were enrolled in the retrospective study.Results A total of 960 hospitalized patients with CHD were enrolled during the observation period. The prevalence of proteinuria and reduced eGFR were 11.04% and 10.52%,respectively.The total CKD prevalence rate was 16.77%,with male of 16.67% and female of 17.11%.There was no significant difference in prevalence rate between male and female( P > 0.05 ).The multi-factors logistic regression analysis showed that diabetes mellitus(OR 2.60,95%CI 1.17-3.29) was risk factor for CHD combined proteinuria.Ten-years older in age( OR1.55, 95%CI1.31-1.83 ), diabetesmellitus ( OR1.69, 95%CI1.15-2.47 ),hypercholesterolemia ( OR 2.89,95% CI 1.49-5.61 ),and hyperuricemia( OR 1.49,95% CI 0.96-2.33 )were risk factors for CHD combined CKD. Conclusion More attention should be paid to the high prevalence of CHD combined CKD.
8.Pharmacological study of apoptosis on antileukemia effect of Carboxymethyl pachymaran
Yong YANG ; Hongxin YANG ; Xiaohong YAN
Cancer Research and Clinic 2001;0(02):-
Objective To study the antileukemia effect of Carboxymethyl pachymaran (CMP) on p388 leukemia mice and its molecular mechanism. Methods After establishing leukemia normal model, they were randomly divided into groups and treated at the same time. FCM and mRNA in situ hybridization(ISH) and S- P assay immunocytochemistry were used for apoptosis and the expression of bcl- 2 mRNA and bcl- 2 protein in peripheral blood lymphocyte samples. Results CMP could prolong the span time of tumor- bearing mice 35.88 %, it was significant for CMP group compared with model group( P
9.TAF to The Hypoimmunity Mice on Effect of T Cell Polarization
Peiyu YAN ; Xiaohong YU ; Deshan ZHANG
Journal of Zhejiang Chinese Medical University 2006;0(02):-
[Objective]To study the effect of T cell groups of CD4+,CD8+,CD4+/CD8+,IL-4,IFN-? in the hypoimmunitymice induced by hydrocortisone to discuss its function of regulating the immune function and CD4+TH cell’s inferior change of group,have offered the experiment basis for clinical practice of TAF.[Method] FACS measured the T lymphocyte phenotype;the level of cytokine IFN-r and IL-4 was detected by ELISA.[Result] TAF can raise CD4+T lymphocyte of hypoimmunitymice,suppress CD8+ T lymphocyte expression,raise CD4+/CD8+ ratio;And can make the level of serum IFN-r obviously enhanced in hypoimmunitymice,and the level of IL-4 was very low.[Conclusion] TAF can rebuild immune function of hypoimmunitymice,promote organism Th0 to split up to Th1,maintain the advantage state of TH1,and strengthen the function of cellular mediated immunoresponse.