Objective To analyze the clinical relationship of progesterone(P) and estradiol(E2) for embryo arrest in early pregnant patients.Methods 118 patients with embryo arrest in early pregnancy were selected and divided into two groups,research group (58 cases,embryo arrest in early pregnancy) and control group (60 cases,threatened abortion but embryo keeping growth by tocolysis).Serum P and E2 were measured and compared between two groups.Receiver operating characteristic curves(ROC) of all indexes were drawn and the areas under the ROC curves were calculated to evaluate diagnostic value.Results Compared to control group,the serum P and E2 were lower in research group(P ＜ 0.05).To diagnosis embryo arrest,the threshold for P was less than 118.4nmol/L,with 93.9％ sensitivity and 87.3％ specificity; while the threshold value for E2 was less than 1110pmol/L,with 95.6％ sensitivity and 90.7％ specificity.Conclusion Detection of serum P and E2 may be helpful for the diagnosis of embryo arrest in early pregnancy,and the serum E2 had the best diagnostic value.

Objective: To explore the effect of sequential external counterpulsation on sudden deafness.Methods: All the patients were treated with sequential external counterpulsation instrument produced by Guangzhou South-China Medical Instrument Company.Results: After treatment,the hearing threshold of 60 cases was all improved,with an increase from 5 to 53 db,and with an average threshold shift of 29?8.7db.86.7% of cases acquired satisfied therapeutic effects except 8 cases whose hearing threshold increased by less than 15db.Conclusion: the results showed that,the treatment of sudden deafness with Sequential External Counterpulsation has good therapeutic effects.Earlier and longer treatment means better effect

Objective To determine the content of hesperidin in Weifukang capsules by HPLC,and to establish the quality standard of Weifukang.Methods HPLC method was performed on C18 column(4.6 ?200 mm,5 ?m).The mobile phase consisted of acetonitrile-sodium dihydrogen phosphate(0.05 mol/L)-phosphoric acid(200 ∶800 ∶0.5).The flow rate was 1.0 mL/min,column temperature was 25 ℃,and the detection wavelength was 283 nm.Results Hesperidin was linear at the range of 0.38 ?g～1.90 ?g(r=0.999 2)the mean recovery rate was 97.88 %,and RSD was 1.69 %.Conclusion This method is effective and reproducible and provides a basis for the quality control of Weifukang capsules.

OBJECTIVE:To evaluate the practice of the Guidelines for Clinical Use of Antibacterials in our hospital. METHODS: 200 medical records of pediatric inpatients who had been discharged from our hospital were randomly sampled between June to December in 2003 (before intervention) and between June to December in 2005 (after intervention) for a statistical analysis in respect of the use of antibacterials in which the pre-designed questionaire on the contrast analysis of clinical application of Antibacterials were filled. RESULTS: After the introduction of the guidelines, the rate of using antibacterials decreased by 17.50%, the rate of combined use of antibacterials decreased by 32.10%, the rate of rational use increased by 22.05%, the rate of susceptibility test increased by 11.84%. The Drug Utilization Index for all the antibacterials was no more than 1 (≤1). CONCLUSION: The use of antibacterials in pediatric inpatients in our hospital tends to be rational, but the rational administration of antibacterials remains to be further improved.

Objective:To analyze therapeutic effect of atorvastatin combined clopidogrel on patients with unstable an‐gina pectoris (UAP) and its influence on prognosis .Methods :A total of 215 UAP patients were randomly divided in‐to atorvastatin group (n=106 ,received atorvastatin based on routine treatment ) and combined treatment group (n=109 ,received atorvastatin combined clopidogrel based on routine treatment ) .Therapeutic effect ,levels of serum high sensitive C reactive protein (hsCRP) ,blood lipids and interleukin (IL)‐6 etc .were compared between two groups .Results:Total effective rate of combined treatment group was significantly higher than that of atorvastatin group (94.5% vs .76.4% ,P<0.01) .Compared with before treatment ,there were significant reductions in levels of hsCRP ,IL‐6 and total cholesterol (TC) in both groups after treatment ,P<0.01 all;compared with atorvastatin group ,there were significant reductions in levels of hsCRP [ (5.35 ± 1.37) mg/L vs .(3.36 ± 1.25) mg/L] ,IL‐6 [ (17.36 ± 4.58) pg/ml vs .(12.28 ± 3.24) pg/ml] ,TC [ (7.69 ± 1.20) mmol/L vs .(4.35 ± 1.20) mmol/L] and TG [ (3.35 ± 1.02) mmol/L vs .(1.29 ± 0.25) mmol/L] in combined treatment group , P<0.01 all .Total inci‐dence rate of adverse cardiac events in combined treatment group was significantly lower than that of atorvastatin group (3.7% vs .16.0% ,P=0.002) .Conclusion:Atorvastatin combined clopidogrel cansignificantly enhance ther‐apeutic effect , effectively inhibit inflammation ,reduce incidence rate of adverse cardiac events in patients with un‐stable angina pectoris .

Objective To analyze the correlation between the blood typing test,irregular antibodies screening of pregnant women and hemolytic disease of newborn(HDN).Methods The ABO blood type and Rh(D)blood type of pregnant women were detected,and the irregular antibodies of pregnant women were screened.The blood type serol-ogy and hemolytic disease were detected in neonates with jaundice.Results In specimens of 2 032 pregnant women with type O blood,their husbands were non -O blood type,after delivery,152 neonates were diagnosed as HDN. Among 2 032 pregnant women with type non -O blood,only 5 neonates were diagnosed as HDN.There was significant difference between the two groups (χ2 =135.4,P <0.01).27 pregnant women with RhD negative type,their hus-bands were RhD positive,after delivery,4 neonates were diagnosed as HDN.Conclusion Pregnant women's blood type and irregular antibody are closely related to neonatal hemolysis disease.So pregnant women's blood type and irregular antibody should be regular project in pregnancy,and so as to prevent neonatal hemolytic anemia caused by blood type of feto -maternal incompatibility.

For the requirements of social development,the medical model has changed from the medical model of organism to the model that of society-mentality-organisms. Thus,pediatrician must change old ideas and old model of thinking,improve knowlege structure and reform medical education model.

The cataloguing of documents of minority nationalities was outlined according to their nature, the literacy and special skills of their cataloguers were pointed out, and the training of their literacy and special skills was elabo-rated.