1.Comparison of one point and two points brachial plexus block below the elbow surgery anesthesia
Chinese Journal of Primary Medicine and Pharmacy 2016;23(16):2523-2524,2525
Objective To compare one point and two points brachial plexus block anesthesia effect below the elbow surgery anesthesia.Methods 70 patients with elective elbow following orthopedic surgery were randomly divid-ed into two points group (group A)and one point group (group B)by random number table,each group had 35 cases.Analgesic effect of anesthesia was compared.The toxic reactions,neurovascular damage and other vascular complications of anesthesia were observed.Results The effective rate and incidence rate of complication of group A were 97.1% and 8.6%,those of group B were 77.1% and 11.4%(χ2 =6.248,0.159).The analgesic effect of group A was significantly better than group B (P <0.05),the incidence of anesthetic complications between the two groups showed no significant difference (P >0.05).Conclusion Axillary brachial plexus block of two points simul-taneous injection has better analgesic effect,block more perfect,it is the first selection of orthopaedics below the elbow surgery anesthesia method.
2.Comparison of 13 emergency biochemical test items′measurement uncertainty between two biochemical analyzers
International Journal of Laboratory Medicine 2015;(22):3268-3270
Objective To investigate the method and application of measurement uncertainty in clinical biochemical tests .Meth-ods The synthetic uncertainty and expanding uncertainty of 13 emergency biochemical tests items were compared between Hitachi 7600 and Beckman DXC800 automatic biochemical analyzer by usingmodel method.The test items included aspartate aminotrans-ferase ,total protein ,albumin ,glucose ,urea ,creatinine ,creatine kinase ,lactate dehydrogenase ,amylase ,potassium ,sodium ,calcium and chloride .Results Measurement uncertainty of aspartate aminotransferase and lactate dehydrogenase were 3 .66% and 3 .51%respectively ,which were the top two on Hitachi 7600 analyzer ;measurement uncertainty of calcium and creatinine were 4 .00% and 3 .90% respectively ,which were the top two on Beckman DXC800 .Compared between the two analyzers ,the test item with the lar-gest difference of measurement uncertainty was sodium(2 .62% ) ,and the second was creatinine(2 .40% ) .The difference of meas-urement uncertainty of the 13 emergency biochemical test items between the two analyzers were relatively small .Conclusion The two analyzer both have good performance ,Model methodis suitable for the evaluation of regular test items′measurement uncer-tainty in clinical biochemical laboratory .
3.Surveillance on the quality of disinfection and sterilization among medical institutes in Xi’an in 201 1-2013
Chinese Journal of Infection Control 2014;(11):681-684
Objective To investigate the status of disinfection and sterilization quality of different levels of medical institu-tes in Xi’an,and improve the management level of disinfection and sterilization of medical institutes. Methods Disinfection and sterilization efficacy of 69 medical institutes were monitored and evaluated according to Standardization for Disinfec-tionTechniques (2002 edition)and Sanitary Standards for Hospital Disinfection (GB15982-1995). Results From 2011 to 2013,2 224 specimens were tested,1 766 (79.41% )were qualified.The qualified rate of tertiary medical institutes was higher than second and below medical institutes (83.67% vs 77.50% ,P= 0.001),the qualified rate between public medical institutes and private medical institutes was not statistically different (79 .64% vs 78 .20% , P= 0.532),the qualified rate of comprehensive medical institutes was higher than specialized medical institutes (80.18% vs 74.92% ,P= 0.030). Of different detected specimens,the qualified rates of disinfectant in use and pressure steam sterilizers (including test pack and process challenge device)were higher (98.46% ,100.00% ,and 98.06% respectively),while the hands of health care workers (HCWs)and glutaraldehyde were lower(58.48% and 43 .28% respectively).Conclusion Disinfection and sterilization quality in different medical institutes in Xi’an is dif-ferent,and different disinfected and sterilized objects are also varied .It is necessary to intensify the management of hand hygiene of HCWs and concentration of glutaraldehyde.
4.Modeling Colon Cancer Gene Logic Network With mRNA Microarray Data
Xiaogang RUAN ; Jinlian WANG ; Hui LI
Progress in Biochemistry and Biophysics 2006;0(08):-
Analysis of cellular pathways and networks in terms of logic relations is important to decipher the networks of molecular interactions that underlie cellular function.A computational approach for identifying lower and higher order gene logic associations was presented on the base of graph coloring theory and applied it to the colon cancer mRNA microarray data.Then the logic relationships of 51 oncogenes and cancer suppressor genes are analyzed and the logic association network of them was constructed.The signal pathway of TGF? from the network model was found and verified by the colon cancer pathway of KEGG.The model reveals many higher order logic relationships of cancer genes.These relationships illustrate the complexities that arise in cancer cellular networks because of interacting pathways.The results show that this method is feasible and is expected to give a reference to the medical molecular biologist.
5.Radical resection of rectal carcinoma by laparoscopic versus conventional laparotomy
Xiaogang GUO ; Jianguo WANG ; Bin ZHANG
Chinese Journal of Postgraduates of Medicine 2009;32(14):9-12
Objective To study the feasibility and curative effect of laparoscopic radical resection of rectal carcinoma. Methods Twenty-eight cases undergoing laparoscopic radical resection (laparoscopic group) and 26 cases undergoing open radical resection (open group) were enrolled from January 2004 to December 2007. The following parameters: operation-related situations, postoperative recovery,result of radical resection, and postoperative outcome were compared between the two groups. Results The blood loss during operation in laparoscopic group was less than that in open group [(148.0±26.5) ml vs (396.0±79.6) ml, P<0.01]. The gastrointestinal tract and urination function in laparoseopic group recovered faster than those in open group[the time of diet in taking was (2.8±0.1) d vs (3.9±0.3) d,the time of detaining urethral catheter was(4.2±0.2) d vs (6.0±0.8) d] (P<0.05). The hospital stay was shorter in laparoscopic group than that in open group [(9.8±1.1) d vs(13.2±2.8) d, P<0.01]. The operation time, the number of cleared lymph nodes and complications of laparoscopic between the two groups were no significant difference (P>0.05). There was no significant difference in local recurrent and beyond metastases rates between the two groups. Conclusion Laparoscopic radical resection of rectal carcinoma parallels with open surgery is in safety and effectiveness, it has less traumatic and blood loss and faster in patients recovery.
6.Comparison of effects of the different dosage MK-801 on recognition memory in rats
Dong WANG ; Weiqing LIU ; Xiaogang CHEN
Chinese Journal of Behavioral Medicine and Brain Science 2013;(6):481-483
Objective To observe the behavioral effects of acute administration of dizocilpine (MK-801) in rats,and to determine an appropriate doses of the drug to mimicking memory deficits of schizophrenia.Methods 192 rats were randomly divided into model groups and control group,and given different doses of MK-801 or saline.Locomotor activity,pre-pulse inhibition (PPI) test and novel object recognition test were studied respectively.Results The spontaneous activity increased in a dose-dependent manner after the treatment of MK-801.The total distances of locomotor activity in 0.3 mg/kg group((127.04 ± 32.35) m) exhibited a significant difference compared with control group((35.34 ± 12.81) m,P < 0.05).MK-801 decreased PPI in dose-dependent manner(P < 0.01).MK-801 0.1 mg/kg((103.45 ± 68.04) %) and 0.3 mg/kg ((41.55 ± 62.93) %) groups showed significant differences compared to control group ((200.39 ± 30.97) %) in PPI.The discrimination index of 0.03 mg/kg group((15.78 ± 6.23) %) and 0.1 mg/kg group((22.42 ± 3.85) %) were lower than that in control group((39.42 ±3.86)%,P<0.05).Conclusion It is necessary for select right doses for model different endophenotypes of schizophrenia by MK-801.0.03 mg/kg of MK-801 is a relatively appropriate dosage to cause recognition memory damage.
7.Effect of B_2O_3 and P_2O_5 on fluorosilicic mica glass-ceramic sintering process
Shun WU ; Zhongyi WANG ; Xiaogang CAO
Journal of Practical Stomatology 1996;0(02):-
Objective: To study the effect of B 2O 3 and P 2O 5 on fluorosilicic mica glass-ceramic sintering process.Methods: Six sets of K 2O-MgO-SiO 2-MgF glass were prepared by using B 2O 3 and P 2O 5as sintering aid respectively. Green bodies of the glass powder were formed by gelcasting and sintered at 800,850,900,950 and 1 000 ℃ for 6 h respectively. The sintering and crystallization behavior were studied by thermal shrinkage , X-ray diffraction (XRD) and SEM.Results:The shrinkage rate of the glass with 2% B 2O 3 and P 2O 5 was the highest ,while that of the glass with 5% P 2O 5 the lowest. The size of the precipitated crystal from the glass ceramics containing 2% B 2O 3 and 2% P 2O 5 was bigger.Conclusion:The density and shrinkage measurements of the sintered bodies show that the glass powder of pure K 2O-MgO-SiO 2-MgF system has poor sinterability, while minor addition (
8.Effect of sintering temperature on the shrinkage and microstructure of dental fluorosilicic mica glass-ceramics with different particle size
Jiang LI ; Xiaogang CAO ; Zhongyi WANG
Journal of Practical Stomatology 1996;0(02):-
Objective:To investigate the effect of sintering temperature on the shrinkage and microstructure of dental fluorosilicic mica glass-ceramic with two different particle size. Methods:Fluorosilicic mica glass powder with average particle diameter of 72.8 ?m was named PO and that with average diameter of 4.5 ?m was named Pm. PO and Pm were molded by cool isostatic pressing technique and then sintered at different temperatures between 600-1 000 ℃. The shrinkage and microstructure of the sintered blocks of PO and Pm were systematically compared with each other. Results:The shrinkage of PO and Pm blocks were all increased as the temperature ascended. However, the shrinkage curves were distinctly different. At the same sintering temperature the shringkage of Pm was larger than that of PO. Moreover, the turning points of temperature (reflecting transition of the sintering mechanisms) of Pm was higher than that of PO. The microstructure observation showed that sintering at 950 ℃ resulted in mica crystal in glass-ceramics and the best compactness of the sintered blocks of both PO and Pm. Conclusion:Sintering glass powder of smaller particle size at 700-850 ℃ may achieve better sintering compactness.
9.Expression and clinical significance of tenascin and CD34 in human cholangiocarcinoma
Lin WANG ; Xiaogang DONG ; Jun YAO
Journal of Xi'an Jiaotong University(Medical Sciences) 1982;0(01):-
0.05).CD34 showed widespread expression in cholangio-carcinoma tissues,but limited in normal bile duct,which showed significant difference(P
10.Effect of immunosuppression on the expression of P-selectin and ICAM-1 in hamster to rat concordant cardiac xenotransplantation
Xiaogang ZHANG ; Yi LU ; Bo WANG
Chinese Journal of Organ Transplantation 2005;0(07):-
Objective To study the role of the expression of P-selectin and intercellular adhesion molecule-1(ICAM-1) in hamster to rat concordant cardiac xenotransplantation.Methods Intra-(abdominal) cardiac transplantation was performed by using SD rats as recipients of Golden Syrian(hamster) hearts.The rats were divided into 4 groups randomly: group I(n=15),unmodified(recipients) were used as control; group II(n=15),splenectomy at day 0;group III(n=15),the rats were treated with cyclosporine A(CsA) 10 mg/kg every day from day 0;group IV(n=15),splenectomy in combined with CsA.The survival of hamster hearts was observed in each group.The xenograft was harvested at rejection and scheduled time in accordance with the experimental design,and analyzed for histology.The expression of P-selectin and ICAM-1 was detected by immunohistochemistry in xenograft after xenotransplantation.Results The mean survival time of the xenograft in group IV was 34.20?8.98 days,which was significantly longer in groups I,II and III (P