Objective To observe clinical efficacy of the combination of Chinese and Western medicine in treatment of neonatal jaundice.Methods 86 cases of jaundice in children with jaundice were randomly divided into study group and control group.Two groups of children were treated with TCM and Western medicine treatment of children in this study group was added based on the decoction of Chinese medicine treatment,two courses,the effects and relevant indicators were compared.Results Compared with the control group,the study group had the markedly effective rate and total effective rate was significantly improved,but not markedly lower,there were statistically significant differences(χ2 = 4.67,5.06,all P＜0.05);At the same time,the study group the average daily value of bilirubin decreased markedly,while the time spent doing back jaundice was significantly lower,there were statistically significant difference(t = 2.91,3.91,all P＜0.05).Conclusion Combination of Chinese and Western medicine in treatment of neonatal jaundice disease,could improve clinical syndrome quickly,and had good effect.

Objective To explore the clinical efficacy of scalp acupuncture on allomnesia post stroke. Methods 60 stroke patients with allomnesia were randomly divided into observation group (n=30) and control group (n=30). The control group accepted routine rehabilitation training for 4 weeks, while the observation group accepted scalp acupuncture in addition. They were evaluated with Rivermead Behavioral Memory Test (RBMT-II) before and after treatment. Results RBMT-Ⅱ scores improved in both groups after treatment (P<0.05), and improved more in the observation group than in the control group (P<0.05). Conclusion Scalp acupuncture may improve the effects of rehabilitation on the memory dysfunction in patients with stroke.

Objective To investigate the correlation between mechanical ventilation (MV) initiation time during cardiopulmonary resuscitation (CPR) and the prognosis of patients with in-hospital cardiac arrest (IHCA) in emergency . Methods Retrospective analysis of clinical records of patients with IHCA in emergency from January 2011 to April 2016 treated in Zhangye People's Hospital of Hexi University was performed. Patients with restoration of spontaneous circulation (ROSC) and were on MV with aged over 18 years were divided into early treated group (≤ 10 minutes) and later treated group (> 10 minutes) according to the initiation time of MV. Corneal reflex, pupillary reflex, pain-avoidance responses and motor response 24 hours after CPR, neurological function and cure rate of the two groups were analyzed. Results 210 patients were selected into our study including 130 males and 80 females (mean age: 60.24±13.17 years). There were no significant differences in gender, age, type of heart rate and etiological factor of cardiac arrest (CA) between the MV early stage group (124 cases) and the MV late stage group (86 cases). The restoration of corneal reflex, pupillary reflex, pain-avoidance responses, motor response and achievement ratio of CPR in early group were higher than those of later group (respectively, 59.68% vs. 31.40%, 59.68% vs. 31.40%, 54.84% vs. 24.42%, 54.84% vs. 24.42%, 70.16% vs. 51.16%, all P < 0.01); The D-dimer levels in the early group patients were significantly lower than those in the later group (μg/L: 478.39±57.21 vs. 510.05±62.83, P < 0.01). However, no statistical difference was observed between the two groups with respect to pH (7.24±0.72 vs.7.13±0.67, P > 0.05); The average hospitalized day of the early group was significantly shorter than that of the later group (days: 24.15±3.04 vs. 30.28±4.17, P < 0.01); Besides, the early group showed a higher survival rate at discharge and had more cases with neurologic level of grade 1-2 than those of the later group (Respectively, 41.94% vs. 26.74%, P < 0.05; 44.35% vs. 15.12%, P < 0.01). Conclusion Initiation MV on IHCA patients in the early stage of CPR (≤ 10 minutes) could help improve the hypoxic condition and prognosis of neurological function, and increase the achievement ratio of CPR.

Objective To observe the effect of Du-moxibustion on cognitive impairment after stroke. Methods 60 patients with cognitive impairment after stroke were randomly divided into control group (n=30) and treatment group (n=30). They were treated with conventional medical treatment and rehabilitation training, the treatment group received Du-moxibustion treatment in addition with once a day, 6 days per week for 8 weeks. They were evaluated with modified Barthel Index (MBI) and Montreal Cognitive Assessment (MoCA) before and after treatment. Results The scores of MBI and MoCA increased after treatment (P<0.05) in both groups and the scores were higher in the treatment group than in the control group (P<0.05). Conclusion Du-moxibustion can further improve the cognitive function and activities of daily living in stroke patients.

Objective To establish a HPLC method for determining the ferulic acid in Baidianfeng Pill. Method ODS column (4.6 mm?250 mm, 5 ?m) was used, the mobile phase consisted of methanol-1% acetic acid aqueous solution(1∶1). The flow rate was 1.0 mL/min and column temperature was at 30 ℃. The detecting wave length was at 320 nm. Results The method was linear with the range of 11.20～84.0 ?g/mL for ferulic acid (r =0.9 998). The average recovery was 98.45%. Conclusion The method is simple, rapid and accurate. It can be used for quantitative deternination of ferulic acid in Baidianfeng Pill.

Objective To investigate the effectiveness of Ender nail fixation in the management of pediatric femoral shaft fractures. Methods A total of 24 children with femoral shaft fracture underwent small incision Ender nail internal fixation followed by 4 weeks of monolateral hip spica-cast immobilization. Results Follow-up observations for 6~24 months revealed no non-union or delayed union. The affected limbs were found within 1 cm shorter or longer than the contralateral in 4 cases. None became lame, and the functions of lower limbs were completely recovered. Conclusions So far as indications and contra-indications of Ender nail fixation are strictly followed, this treatment for femoral shaft fractures in children of age 5~10 years gives characters of small incision, anatomic reduction, unimpaired periosteum, short hospital stay, and quick functional recovery.

Objective To summarize our experiences on open heart surgery through the right subaxillary small incision. Methods Between March 2001 and June 2008,612 patients with congenital heart diseases were treated by open surgery trough a right subaxillary small incision via hypothermic cardiopulmonary bypass. The incision was made from the posterior axillary line at the axilla to the middle axillary line a the fifth intercostal space (4-8 cm in length),and then the intercostal muscle was cut at the inferior edge of the fourth rib for the entrance into the chest cavity. In this series,165 patients had ASD,403 had VSD,35 had ASD complicated with VSD,3 showed PECD,and 6 were found as PAPVC. Results The mean cardiopulmonary bypass time was (25.0?5.5) min,402 of the patients (65.6%) need no blood transfusion. The mean hospital stay was (6.0?4.5) d,no patient died in hospital. The 420 patients were followed up for 5 to 80 months (mean 47 months). During the period,cardiac ultrasonography showed good outcomes in the patients. No complications or death were detected. Conclusions Right subaxillary small incision is a safe and minimally invasive method for the treatment of ASD and VSD with quick recovery,less hemorrhage,shorter hospital stay,less complications,and satisfying cosmetic outcomes.

Objective To study expression of hypoxia inducible factor 1? (HIF 1?) in the lungs of hypoxic rats and to explore the role of HIF 1? in the pathogenesis of hypoxic pulmonary hypertension Methods Twenty Wistar rats were randomly divided into control group and hypoxia group The models of hypoxic pulmonary hypertension were established by exposure to hypoxia for 4 weeks according to our laboratory protocol Digoxin labelled cRNA probe for HIF 1? was prepared by in vitro transcription Northern blot was performed by using the HIF 1? cRNA probe and In situ hybridization was also conducted with rat lung tissue sections Results Northern blot hybridization showed minimally positive in the lung tissue of control group ,but strongly positive in hypoxia group In situ hybridization analysis with hypoxic rat lung tissue revealed that HIF 1? mRNA was expressed in bronchial epithelial cells (strongly positive reaction) and peribronchial proliferative lymphomatic tissue (weakly positive reaction),casually in alveolar wall cells (weakly positive reaction),but not in pulmonary arterial endothelium and smooth muscle cells Conclusions Our data suggested that chronic hypoxia could induce pulmonary hypertension characterized by pulmonary vascular remodeling HIF 1? mRNA expression was elevated in the lungs of rat under hypoxic condition HIF 1 may be involved in the pathophysiological changes in response to hypoxia and play an important role in the development of hypoxic pulmonary hypertension