1.IL-17, IL-17 receptor and mycoplasma pneumoniae infection
International Journal of Pediatrics 2012;(6):621-623
With the development of mycoplasma pneumonia (MP) pathogenesis research,the dynamic observation of changes of cytokines on judgement of the infection of mycoplasma is of certain guiding significance.Domestic and foreign studies showed that MP infection was closely related with IL-17 and its receptor.IL-17 and its receptor may be involved in neutrophil recruitment,and in resistance to MP infection on the immune response.In this paper,the relationship between IL-17and its recepter and mycoplasma infection are reviewed.
2.To Develop the Medical Simulation Education and to Build a Harmonious Environment of Clinical Education
Chinese Journal of Medical Education Research 2003;0(03):-
With the changes in medical model and the enhancement of ethical standard as well as the patients' awareness of right protection,clinical teaching resource shortages have been increasingly prominent.This article analyzes the characteristics and status of clinical medical education and points out that the development of medical simulation education has great significance for building a harmonious clinical training environment centering on the content classification,functional positioning and outstanding advantage of medical simulation education.
3.Effect of fitness Qigong (Yi Jinjing) on blood lipid and free radical metabolism of the elder women
China Journal of Traditional Chinese Medicine and Pharmacy 2006;0(09):-
Objective:To explore the effect of Fitness Qigong(Yi Jinjing)exercise on blood lipid and free radical metabolism of the elder women.Methods:The subjects of this experiment were 64 elder women who were divided into 2 groups randomly:exercise group(34 cases)and control group(30 cases).The exercise group practiced 40-50min pre time,six times pre week for six months,and the control group had no exercise with collective or individual scheme.The indexes of TC,TG,HDL,LDL,SOD,GSH-Px and MDA of the elder women were measured before and after 6-month exercise.Results:After six months Yi Jinjing exercise,the exercise group showed increase in HDL(P0.05),increase in SOD and GSH-Px(P0.05).Conclusion:Fitness Qigong(Yi Jinjing)exercise had the positive effects on blood lipid metabolism,and can suppress lipid peroxidation and maintain high antioxidative capacity of elder female individuals.
4.Serotypes of Ureaplasma Urealyticum Intrauterine Infection with Pregnancy Outcome and Placental Villus Ultrastructural Observation.
Journal of Medical Research 2006;0(01):-
Objective To evaluate the relationships between serotypes of U.urealyticum intrauterine infection with outcome pregnancy and placental villus ultrastructural transform.Methods The placental tissues from 45 cases with spontaneous abortion,34 cases of high-risk pregnancy,including 6 premature delivery and 28 PROM patients(study group)and 51 normal pregnant patients(control group)were isolated,cnltured and performed.Serotypes of U.urealyticum were identified by a metabolic inhibition test.The positive cases placental tissue of U.urealyticum were preformed ultrastructural observation by electron microscope.Results Total positive rate 63.3%(50/79)in the study group,showing significant difference from that of control group(47.1%,24/51,P
5.The application and prospects of 3D technology in medical education
Meige LIU ; Yu ZHANG ; Xiaodan LI
Chinese Journal of Medical Education Research 2016;15(5):533-537
In recent years,there is an increasing focus on three Dimensional (3D) Technology in medical field.The article summarizes the progress of 3D printing technology such as medical models,implantable prosthetics,biological engineering,est.,analysis application and effects of 3D technology abiding by the characteristics of clinical medical education.Considering the situation of domestic medical education,therefore,it points out that it is of broad application prospects and great practical significance to develop 3D medical education due to establishing a harmonious teaching environment,providing simulated clinical practice opportunities,activating the brain proportionately and stimulating students learning enthusiasm.
6.Correction of cryptotia and cartilage malformation with Z-plasty without skin grafting.
Jafeng LIU ; Xiaodan LI ; Jiaming SUN
Chinese Journal of Plastic Surgery 2016;32(1):43-45
OBJECTIVETo explore the curative effect of Z-plasty without skin grafting for correction of cryptotia.
METHODSTwenty-five cases (29 ears) with cryototia were corrected by Z-plasty without skin grafting in our department from June 2009 to January 2014. A Z-shaped incision with one arm on the back of antihelix and the other arm on the edge of hair was made on the back of ear and scalp. The adhesion on the back of antihelix cartilage was dissected and the cartilage framework was lifted and re-positioned. The postauricular flap was transferred to cover the wound on the back of antihelix. The other flap was transferred to cover the remnant wound and correct the malformation of cryptotia.
RESULTSAll the patients were followed up from 6 months to 1 year with stable and symmetric appearance.
CONCLUSIONSThe shape of auricle is natural after operation without skin grafting. It is a simple and ideal method for the treatment of cryptotia.
Ear Cartilage ; abnormalities ; surgery ; Ear, External ; abnormalities ; surgery ; Humans ; Skin Transplantation
7.Total auricular reconstruction with single big expander at dual plane through incision at remnant ear.
Liu JIAFENG ; Li XIAODAN ; Sun JIANMING
Chinese Journal of Plastic Surgery 2015;31(4):251-254
OBJECTIVETo investigate the feasibility and advantages of total auricular reconstruction with single big expander at dual plane through incision at remnant ear.
METHODS52 patients with microtia were treated. Through incision at remnant ear, one big expander (150 ml) was implanted in the post-auricular area beneath the superficial facial in the hairless area, and above the superficial fascia in the area with hair. In the second stage, total auricular was reconstructed with autologous cartilage framework and expanded skin. Skin graft was not necessary. Another 32 paitents with single big expander above the superficial fascia were used as control. The downward shift distance of expanders, the appearance of auriculocephalic sulcus and complication were recorded in order to assess the effect of these two methods.
RESULTSThe downward shift distance of expanders in the dual plane group (0.7 ± 0.3) cm were lower than that in the control group (1.3 ± 0.4) cm, showing significant difference (P < 0.05). After a follow-up period of 6-12 months, shallow auriculocephalic sulcus was presented in 5 patients of the dual plane group and 12 patient of the control group. The shallow auriculocephalic sulcus was cut to make it deeper and covered with full skin graft.
CONCLUSIONSDual plane skin expansion could reduce the downward shift distance of expander. Adequate skin on the upper part of expander could make satisfactory auriculocephalic sulcus.
Cartilage ; transplantation ; Congenital Microtia ; surgery ; Feasibility Studies ; Hair ; Humans ; Reconstructive Surgical Procedures ; methods ; Skin Transplantation ; methods ; Subcutaneous Tissue ; Surgical Flaps ; trends ; Tissue Expansion ; methods ; Tissue Expansion Devices
8.Comparison of effect of lanceolata and astragalus on electrocardiogram of rats with experimental myocardial ischemia
Xiaodan ZHANG ; Lin LIU ; Xin TONG
Chinese Journal of Tissue Engineering Research 2005;9(47):142-143
BACKGROUND: Lanceolata and astragalus can improve myocardial ischemia, which are widely used in clinics.OBJECTIVE: To compare the effects of extract of lanceolata and astragalus on electrocardiogram (ECG) of rats with experimental myocardial ischernia.DESIGN: Completely randomized and controlled study.SETTING: Pharmacological College of Harbin Commerce University.MATERIALS: The experiment was carried out at the Laboratory of Pharmacological College of Harbin Commerce University from September to December 2002. Totally 30 healthy adult Wistar rats were divided randomly into 3 groups: control group, lanceolata group and astragalus group with 10 in each group.METHODS: ① After anesthesia, lead ECG Ⅱ of rats was recorded.30 g/kg saline, 30 g/kg lanceolata extract and 30 g/kg astragalus extract [extract of lanceolata and astragalus (raw drug: 1 g/mL)] were injected into rats in the control group, lanceolata group and astragalus group respectively. After 1-3 minutes, 0.5 U/kg pituitrin was injected intravenously (for model of myocardial ischemia), and then saline was used to dilute from 0.1to 0.2 mL for 10-second injection. Changes of ECG after injection of pituitrin were recorded with LMA-2B Ⅱ physiological recorder (migration of T wave and ST section and change of heart rate). ② Differences of data were compared with t test.MAIN OUTCOME MEASURES: Height of T wave and Migrations of ST section and changes of heart rate of ECG of rats before and after medication.RESULTS: Data of totally 30 rats was entered the final analysis. ①Height of T wave: The height was higher after medication than that before medication in three groups (P < 0.01), but that in astragalus group was obviously lower than that in lanceolata group [(1.63±3.81), (2.18±2.93) mm,P < 0.01]. ② Heart rate: The rate was lower after medication than that of before medication in three groups (P < 0.01), and that in astragalus group was obviously lower than that in lanceolata group [(212.21 ±5.01),(221.18±5.66) time/minute, P < 0.01]. ③ Height of ST section: There were not significantly different in three groups (P > 0.05), and the difference was not obvious before and after medication (P > 0.05).CONCLUSION: ① Both astragalus and lanceolata can protect experimental myocardial ischemia induced by pituitrin. ② Effect of lanceolata on reduction of T-wave height is stronger than that of astragalus, but the effect of lanceolata on reduction of heart rate is weaker than that of astragalus.
9.The transformation and adaptation of medical English terms in Chinese language and culture
Wei LIU ; Qian WANG ; Xiaodan ZUO
Chinese Journal of Medical Education Research 2011;10(11):1393-1395
Based on the word-formation of Medical English terms,this paper gives a comprehensive analysis of their transformation and adaptation in Chinese language and culture.Three major factors are discussed for the application and diversification of medical English terms,including the language family in translation,linguistic context,situational context and cultural context.
10.Clinical correlative factors of malignant cystic pancreatic tumors
Xiaodan LI ; Yujian LIU ; Liwei ZHU
Chinese Journal of Digestive Surgery 2012;11(4):343-345
Objective To investigate the clinical correlative factors of malignant cystic pancreatic tumors.Methods The clinical data of 45 patients who received cystic pancreatic tumor resection at the General Hospital of Tianjin Medical University from May 2000 to May 2011 were retrospectively analyzed.All patients were divided into benign tumors + precancerous lesions group (35 patients) and malignant tumor group (10 patients).The clinical symptoms and imaging features of cystic pancreatic tumors were analyzed.All data were analyzed by chisquare test or Logistic regression analysis.Results Abdominal pain,jaundice,emaciation,nausea and vomiting were observed in 23 patients (51%),and 22 (49%) patients had no clinical symptoms.The clinical features of benign pancreatic cyst included pancreatic calcification and pancreatic divisum,while the clinical features of malignant pancreatic cystic tumors were nodules,swelling of lymph nodes,dilation of biliary and pancreatic duct.The results of univariate analysis showed that age ≥ 60 years,presence of symptoms,jaundice,emaciation,dilation of pancreatic duct were the correlative factors of malignant cystic pancreatic tumors ( x2 =4.220,4.294,4.645,7.705,4.645,P < 0.05 ).The results of multiple logistic regression analysis found that age ≥60 years,dilation of pancreatic duct and presence of clinical symptoms were the correlative factors of malignant cystic pancreatic tumors ( OR =1.573,2.674,2.723,P < 0.05).Conclusion Age≥60 years,dilation of pancreatic duct and presence of clinical symptoms are the correlative factors of malignant cystic pancreatic tumors.