1.Multiple molecular targets of resveratrol: anti-breast cancer mechanisms
Fengqi QIU ; Xiaochao DING ; Ping MA
Journal of International Oncology 2013;(2):114-117
Resveratrol,which is produced by natural plants,has various biological activities,including anti-inflammatory,antioxidant and anticancer properties.Recently,it is found that resveratrol can inhibit the proliferation and promote the apoptosis of breast cancer through multiple molecular targets,which provides a theoretical basis for resveratrol used in the treatment of breast cancer.
2.Analysis of children’ s health and influential factors in Nujiang prefecture, Yunnan
Yongchao CHEN ; Fang WANG ; Bin CAO ; Xiaoxi LIU ; Xiaochao XU ; Bo ZHANG ; Xue DING
Chinese Journal of Health Policy 2014;(2):57-64
Objective:To determine children ’ s health status and influential factors in Nujiang prefecture , Yun-nan.Methods:Rickets morbidity rate , growth retardation rate , and low-weight rate were selected as the key indica-tors to calculate the sample size by using four-stage-sampling procedure .The data was collected through questionnaire survey, in-depth interviews, and focus-group discussions .χ2 test and qualitative analysis were used to analyze the quantitative and qualitative data .Results:The infant mortality rate was 13.14 %in 2011, which was 1.1 and 1.15 times more than the national and provincial average .The mortality rate of children under five was 16.35%in 2011, which was 1.05 and 1.13 times more than the national and provincial average .It was also 2.19 times more than the average in developed countries .The prevalence of medium and severe malnutrition in children under five was 2 .32%, which was 1 .54 times more than the national average .The incidence of low birth weight was 1 .41%.The research shows that the rates of rickets , growth retardation , and low-weight were 36.13%, 25.81%and 20.98%,and nutritional diseases are more serious .Conclusion:There are serious health problems for children in Nujiang pre-fecture, especially nutritional diseases .Influential factors include health policy and system , economic development, customs, geography, health service capacity , and parental health knowledge Suggestion:The government should im-prove top-level design , strengthen policy support , and develop the local economy in order to solve the social and poli-cy environment factors .Institutions and human capacity should be strengthened , access and quality of services should be improved , health education should be popularized , and health awareness and behaviors should be improved .
3.A framework for evaluating the comprehensive intervention for children’ s health based on the program theory
Xue DING ; Fang WANG ; Bin CAO ; Xiaochao XU ; Bo ZHANG ; Xiaoxi LIU ; Yongchao CHEN
Chinese Journal of Health Policy 2014;(2):65-71
In this paper , we summarize the theoretical models and research progress about program evaluation and practical situation of children ’ s health in Nujiang prefecture .We then develop a framework for comprehensively evaluating the intervention for children ’ s health based on program theory .This framework comprises the outside pro-gram environment , intervention action modules and change modules , and assessment techniques environment .The e-valuation mainly includes leading agencies , implementing agencies , coordinating agencies , coordination/implementa-tion personnel , intervention and service standards , the environment and atmosphere , target populations , interven-tions, determinants, outcome and effect .
4.The design of a comprehensive intervention project for children ’ s health in Nujiang Prefec-ture,Yunnan
Fang WANG ; Xiaoxi LIU ; Bin CAO ; Xiaochao XU ; Bo ZHANG ; Xue DING
Chinese Journal of Health Policy 2014;(2):50-56
The Theory of Change holds that the change in a project ’ s effectiveness can be derived from the changing process in the certain context .Only after analyzing changes caused by a project and the possible changing path or hypothesis can we determine the real cause of an effect .In 2012, the maternal, child and community health department of the former Ministry of Health began a comprehensive intervention project for children ’ s health in Nu-jiang Prefecture .The project was designed to explore modes and mechanisms for improving children ’ s health in the west, poverty and ethnic minority areas through cooperation at the national , provincial, and prefecture levels.Based on the Theory of Change , this article describes the logical framework of the comprehensive intervention project .In or-der to lay the foundation for improving the project design , ensuring the implementation of the project and conducting the follow-up monitoring and evaluation , we also expound the goals , implementation strategies , and intervention measures, project activities and output , implementation routes .